Audiology: Alport Syndrome Alport Syndrome Term Paper

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Other studies have found "no statistically significant average difference between left and right ears for average values of TOAE (transitory otoacoustic emissions) response amplitude with no contralateral acoustic stimulation in patients with Alport's syndrome. (Abreu Alves & al, 2008)" Auditory brainstem response results for Alport Syndrome patients indicate the cochlea as the site of damage, with dramatic alterations of the stria vascularis.

Hearing loss from Alport Syndrome complications is usually permanent. Recommendations for patients include: urine testing alongside SNHL testing; otologist involvement at all stages of treatment once hearing loss presents; counseling and education to enhance coping skills; instruction for lip reading and sign language; use of hearing protection in noisy environments; and hearing aid prescription.

References

Alport Syndrome Foundation, s. (2010). What is Alport Syndrome? Retrieved 12 5, 2010, from www.alportsyndrome.org: http://www.alportsyndrome.org/what-is-alport-syndrome/

Favor, J., Gloeckner,...

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(2007). Type IV Procollagen Missense Mutations Associated with Defects of the Eye, Vascular Stability, the Brain, Kidney Function and Embryonic or Postnatal Viability in the Mouse. Genetics, 725+.
Kashtan, C. (2010, 07-15). Collagen IV-Related Nephropathies (Alport Syndrome and Thin Basement Membrane Nephropathy. Retrieved 12 5, 2010, from www.ncbi.nlm.nih.gov: http://www.ncbi.nlm.nih.gov/books/NBK1207/#alport

Martin, F. (1975). Introduction to Audiology. Englewood Cliffs, NJ: Prentice-Hall.

NIH, s. (2009, 04). Genetic Conditions: Alport Syndrome. Retrieved 12 5, 2010, from ghr.nlm.nih.gov: http://ghr.nlm.nih.gov/condition/alport-syndrome

NKF, s. (2010). Alport Syndrome. Retrieved 12 5, 2010, from www.kidney.org: http://www.kidney.org/atoz/content/Alport.cfm

Northern, J., & Downs, M. (1974). Hearing in Children. Baltimore: Williams & Willkins.

Osaretin, a., & al, e. (2009). Alport's Syndrome. Saudi Journal of Kidney Diseases and Transplantation, 1087+.

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