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In order to make an actual determination as to the relationship between purine metabolism and autism spectrum disorders, this research involved testing a gene known to affect purine metabolism and that therefore had a possible connection to causing autism (Hettinger et al. 2007). Specifically, the researchers identified the adenosine deaminase gene as the possible culprit for some cases of autism spectrum disorder linked to urine metabolism, as other issues with this gene develop similar metabolic and construction problems with other proteins and enzymes (Hettinger et al. 2007). Previous studies had noticed some correlation in sub-standard operation of this gene and certain cases and types of autism spectrum disorder, though there was not enough evidence to establish a causal relationship (Hettinger et al. 2007). This study was one of the first to directly examine the gene and its relationship...
2007).
In order to test this relationship, the researchers gathered information on 126 different sibling pairs, all of whom came from families where two or more children had autism or an autism spectrum disorder, including the extent and type of their disorder and the measuring of certain genetic markers (Hettinger et al. 2007). These results were then compared to the genetic results of a control group of comparable size, and the differences in genetic makeup between the two groups were analyzed to determine any noticeable differences (Hettinger et al. 2007). Unfortunately, the evidence was still basically inconclusive; although there is some indication that the gene can have an effect on certain types of autism spectrum disorders, there was not a significant enough difference in the expression of the specific gene in question to establish…
Regardless of the nebulous causes of autism spectrum disorders, the pathophysiology of the disease is generally agreed on to consist of certain neurotransmitter impairments, and/or disruptions of normal brain and central nervous system development (Hettinger et al. 2007). Certain case studies suggest that disruptions in the pathway concerning purine metabolism can have a detrimental effect on the development of other pathways in the central nervous system, possibly causing autism spectrum disorders (Hettinger et al. 2007). These case studies do not provide enough evidence by themselves that purine metabolism can be implicated in autism development, however.
In order to make an actual determination as to the relationship between purine metabolism and autism spectrum disorders, this research involved testing a gene known to affect purine metabolism and that therefore had a possible connection to causing autism (Hettinger et al. 2007). Specifically, the researchers identified the adenosine deaminase gene as the possible culprit for some cases of autism spectrum disorder linked to urine metabolism, as other issues with this gene develop similar metabolic and construction problems with other proteins and enzymes (Hettinger et al. 2007). Previous studies had noticed some correlation in sub-standard operation of this gene and certain cases and types of autism spectrum disorder, though there was not enough evidence to establish a causal relationship (Hettinger et al. 2007). This study was one of the first to directly examine the gene and its relationship to autism (Hettinger et al. 2007).
In order to test this relationship, the researchers gathered information on 126 different sibling pairs, all of whom came from families where two or more children had autism or an autism spectrum disorder, including the extent and type of their disorder and the measuring of certain genetic markers (Hettinger et al. 2007). These results were then compared to the genetic results of a control group of comparable size, and the differences in genetic makeup between the two groups were analyzed to determine any noticeable differences (Hettinger et al. 2007). Unfortunately, the evidence was still basically inconclusive; although there is some indication that the gene can have an effect on certain types of autism spectrum disorders, there was not a significant enough difference in the expression of the specific gene in question to establish a firm relationship (Hettinger et al. 2007).
Onion field" by Joseph Wambaugh True crime novels often have a way of fictionalizing the action to too great an extent. The people in the book become caricatures of the people that they really are, and it makes the book read more like a fictionalize representation than a real story. Unfortunately, truth is stranger than fiction, and many times the author is actually attempting to tone down some of the
J.C. Penney News Is Bigger Than Lawsuit Decisions, Revenue Losses, and Resignations - Mark Cuban's Stock Purchase Is Better Than Money for J.C. Penney's Recovery (JCP, MSO) Organizational context: J.C. Penney J.C. Penney is one of the most famous and renowned of the major U.S. department stores. It is well-known for its image of Americana and its reasonable prices. However, within this particular market segment, J.C. Penney is facing increasingly stiff competition
The growing need for interdisciplinary education in the sciences has been recognized, as well, since students have often limited themselves to a specialized field without gaining the required skill sets to undertake broader issues. As the world becomes more complex, technology faster and business increasingly competitive, organizations are going to need "Renaissance people" who have a broad background in different areas, so they can clearly see the gestalt of a
" (Liu, 90) As the author notes, his feeling of coming to Chinatown was that of a merely curious tourist, not that of a native who links himself to his past or origins. Like other writers on the subject of Asian-Americans, Liu also noted that they seem to be a special case, the "new Jews," that is a minority that is neither black nor white. Racism is usually seen as bipolar,
There are circumstances as Crane a. And Matten D. (2004) discussed showing that the compromise on standards is likely to occur owing to the idea of gifts. Contrary to this notion, in china gifts are not given to influence one decisions but as a norm of appreciating. While no specific standard to the gift is required, the gift works only to share one appreciation of the business undertaken. Looking at the
Malcolm X's contributions to the civil rights movement cannot be viewed in isolation, without taking into account his influences and contextual variables. By the time Malcolm X wrote his Autobiography, he had already developed a well-articulated and logical political philosophy. His influences as stated in his autobiography include Marcus Garvey, from where Malcolm X's father learned the ideas he passed onto his son. It was Elijah Muhammad and the Nation