Yet, they fail to do this in a manner that can be consumed by a wide readership. The need to review is based on that issue; the need to revise it is based on the very functional application of the research finding. Science can be interpreted in many ways, and the more common the denominator of language, the more widely available the knowledge will be. To keep such findings at the level where the researchers work from would be fine if that knowledge was only applicable to their inner laboratories. However, the findings have a very wide and very important application in the real world: to help cancer patients suffer their disease and treatment more tolerably. Better health outcomes result not only from better technologies, but also from an overall better experience by the patient undergoing difficult treatments. This is a serious issue that the authors have failed to note, instead putting forth for publication a wealth of mathematical models that may not be easily digested by the breadth of the readership. It would be a shame to see such a valuable finding not be followed...
The math and the graphs are fine demonstrations, yet the importance of the interpretations needs to be brought out in full strength through use of language, not mathematical symbols.
Overall Rating:
Technical: Outstanding
Quality: Good
Organization and Writing of the Paper: Deficient
Originality of the Paper: Very Good
Significance of the Paper: Outstanding
Overall Recommendation: Paper would be groundbreaking if written in prose and with highlights upon the real application in clinical practice for the benefit of the patient.
Reference
Webb, S., & Nahum, a. (1993). A model for calculating tumour control probability in radiotherapy including the effects of inhomogeneous distributions of dose and clonogenic cell density. Physics in Biology and Medicine, 653-666.
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