Case Study Undergraduate 711 words Human Written

Gender Differences in Patients with Alzheimer's Disease

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Problem Statement Alzheimers Disease (AD) is a debilitating and progressive neurodegenerative disorder estimated to affect over 5 million women in the United States, yet recent research has shown that many cases go undiagnosed (Royse et al., 2021). This leads to significant health inequalities for American women because of their increased risk for diagnosis...

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Problem Statement

Alzheimer’s Disease (AD) is a debilitating and progressive neurodegenerative disorder estimated to affect over 5 million women in the United States, yet recent research has shown that many cases go undiagnosed (Royse et al., 2021). This leads to significant health inequalities for American women because of their increased risk for diagnosis due to their demographic factors (de Lange, 2020; Dubal, 2020; Majoka & Schimming, 2022; Peeters et al., 2022). Research has also suggested that American women with AD experience greater disability and require more assistance than their male counterparts, which further highlights the issue of inequity in healthcare for women (Zuo & Heflin, 2022).

Given the increasing prevalence of AD in the United States, there is a critical need to understand the disproportionate impacts of the condition on American women (Peeters et al., 2022). This need becomes even more pronounced when a consideration of gender is factored in, as there is evidence that women may be more vulnerable to the negative effects of AD due to the specific risks they face (de Lange, 2020; Hu et al., 2022). Therefore, a study of the prevalence and effects of Alzheimer’s Disease among American women is necessary to inform an understanding of the impact of the condition on this population and to identify strategies for mitigating its negative consequences. Such a study would contribute to the existing body of research on AD and provide valuable information to support the development of policies and programs tailored to meet the needs of American women affected by the condition. Plus, this research could be used to inform theory on gender differences in the diagnosis, treatment, and care of individuals with AD and to better understand how gender may moderate the impact of the condition.

References

Beckman, D., & Morrison, J. H. (2021). Towards developing a rhesus monkey model of early Alzheimer’s disease focusing on women’s health. American Journal of Primatology, 83(11), 1–7.

de Lange, A. G. (2020, August). Women's brain aging: Effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer's disease. Human Brain Mapping, 41(18), 5141-5150.

Dubal, D. B. (2020). Sex difference in Alzheimer's disease: An updated, balanced and emerging perspective on differing vulnerabilities. Handbook of Clinical Neurology, 175, 261-273.

Hu, Y., Carr, P. R., Liew, D., Broder, J., Callander, E. J., & McNeil, J. J. (2022). How does the onset of physical disability or dementia in older adults affect economic wellbeing and co-payments for health care? the impact of gender. BMC Health Services Research, 22(1), 701.

Kimura, A. et al. (2019). Malnutrition is Associated with Behavioral and Psychiatric Symptoms of Dementia in Older Women with Mild Cognitive Impairment and Early-Stage Alzheimer’s Disease. Nutrients, 11, 1951.

Lincoln, K. D., Chow, T., Gaines, B. F., & Fitzgerald, T. (2021). Fundamental causes of barriers to participation in Alzheimer’s clinical research among African Americans. Ethnicity & Health, 26(4), 585–599.

Majoka, M. A. & Schimming, C. (2022, June).Effect of Social Determinants of Health on Cognition and Risk of Alzheimer Disease and Related Dementias. Clinical Therapeutics, 43(6), 922-929.

Peeters, G., Katelekha, K., Lawlor, B., &Demnitz, N. (2022). Sex differences in the incidence and prevalence of young?onset Alzheimer’s disease: A meta?analysis. International Journal of Geriatric Psychiatry, 37(1), 1–9.

Royse, S. K., Cohen, A. D., Snitz, B. E., &Rosano, C. (2021). Differences in Alzheimer’s Disease and Related Dementias Pathology Among African American and Hispanic Women: A Qualitative Literature Review of Biomarker Studies. Frontiers in Systems Neuroscience, 15, 685957.

Sanfilippo, C. (2019, May 15). Middle-aged healthy women and Alzheimer's disease patients present an overlapping of brain cell transcriptional profile. Neuroscience, 406(15), 333-344.

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