HepC Hepatitis C is a potentially fatal liver disease transmitted by a bloodborne virus. In fact, Hepatitis C is " the most common chronic bloodborne infection in the United States," with more than three million exhibiting a chronic infection (Centers for Disease Control and Prevention). All hepatitis diseases refer to the inflammation of the liver,...
HepC Hepatitis C is a potentially fatal liver disease transmitted by a bloodborne virus. In fact, Hepatitis C is " the most common chronic bloodborne infection in the United States," with more than three million exhibiting a chronic infection (Centers for Disease Control and Prevention). All hepatitis diseases refer to the inflammation of the liver, and are caused by viral infections. Hepatitis a, B, and C. are the most common of the hepatitis diseases, but other rarer forms D. And E. do exist.
The Hepatitis C virus, abbreviated as HCV, is "among the most serious" of the hepatitis family of diseases because of its deleterious effect on the liver (Mayo Clinic). Whereas Hepatitis a can be transmitted through contaminated food and drink, Hepatitis C is transmitted almost exclusively via bodily fluid. Sharing intravenous needles, coming into contact with the bodily fluids of an infected individual, and being born to a mother with Hepatitis C are all possible methods of disease transmission.
Blood is the most certain method of transmission; sexual transmission is less likely because " HCV is not efficiently transmitted sexually," (Centers for Disease Control and Prevention). Similarly, incidental or occupational exposure to infected blood or bodily fluid is an ineffective means of transmitting the virus. The most likely method of contracting the HCV is via "large or repeated percutaneous exposure to infected blood," such as "transfusion of blood from unscreened donors or through use of injecting drugs," (Centers for Disease Control and Prevention).
Remarkably, "most people don't know they have the hepatitis C infection until liver damage shows up, decades later, during routine medical tests," (Mayo Clinic). This makes it easier to spread the disease, as an infected person remains unaware that they carry the HCV. Although the symptoms of Hepatitis C can remain dormant for more than ten years, a simple blood test can predict its presence in an individual with risk factors.
Left untreated, Hepatitis C can lead to serious complications including liver cancer, scarring of the liver (cirrhosis), and liver failure requiring a transplant. Methods of prevention include reducing risk factors, as no vaccine for Hepatitis C exists. Some individuals do manifest mild symptoms prior to the onset of liver damage, including fatigue, nausea, upset stomach, loss of appetite, or fevers.
Because many of these symptoms are vague and could be attributed to the flu and other common infections, a diagnosis of Hepatitis C may still not be made until more overt symptoms of liver damage are noted. For example, jaundice is one of the symptoms of liver distress. The yellowing of eyes and skin is an indicator that one of the hepatitis viruses has infected the individual's body. Once infected, an individual may "clear the virus from their bodies in a few months," (National Digestive Diseases Information Clearinghouse (NDDIC)).
About 15% of individuals naturally clear the virus in this way (United States Department of Veteran Affairs). Thus, a diagnosis of Hepatitis C might not warrant any treatment intervention other than close monitoring of liver function. When the virus remains in the body, the disease progresses to its chronic phase. According to the Centers for Disease Control and Prevention, "chronic HCV infection develops in 70% -- 85% of HCV-infected persons." Of chronically infected individuals, 60% -- 70% "have evidence of active liver disease," (Centers for Disease Control and Prevention).
About 17% of chronically infected individuals will develop cirrhosis and about 2% will develop liver cancer (United States Department of Veteran's Affairs). Treating chronic Hepatitis C usually entails pharmaceutical intervention. A combination of two antiviral drugs, peginterferon and ribavirin, is currently the most effective treatment intervention. Other methods include administering long-acting (pegylated) interferon by itself; or administering a short-acting version of interferon with ribarvirin (United States Department of Veteran's Affairs). Using these two drugs, peginterferon and ribavirin, the treatment program usually lasts between 24 and 48 weeks (NDDIC).
After one round of treatment, the doctor tests for HCV and if the virus is still present the second round of drugs is administered (Mayo Clinic). "The peginterferon is taken through weekly shots and ribavirin is taken daily by mouth," (NDDIC). The side-effects from the peginterferon program include flu-like symptoms and depression (Mayo Clinic). Some side-effects can be so serious that "treatment must be delayed or stopped in certain cases," (Mayo Clinic). Therefore, treatment of Hepatitis C is not taken lightly.
If Hepatitis C has progressed to the point where the individual's liver is damaged beyond repair, a transplant may be necessary. Because the HCV usually remains active after the transplant, the recipient will still need to take.
The remaining sections cover Conclusions. Subscribe for $1 to unlock the full paper, plus 130,000+ paper examples and the PaperDue AI writing assistant — all included.
Always verify citation format against your institution's current style guide.