Lady Macbeth's plan to reach the throne includes the manipulation of her husband. She is well aware that he loves her, respects her opinion, and wastes no time using this information. The fact that she would manipulate her husband this way is a tragedy because Macbeth cannot see what she is doing to him. She attacks when he conveys a sense of uneasiness in regard to killing Duncan. She states:
Art thou afeard
To be the same in thine own act and valour
As thou art in desire? Wouldst though have that
Which thou esteem'st the ornament of life.
And live a coward in thine own esteem. (I.vii.39-43)
This is a clear example of how she will do whatever she needs to do to reach the throne even if it means belittling her husband. She knows that he wants to be perceived as a strong man rather than a weakling that is afraid of anything. Later in the play she tells him, "But screw your courage to the sticking-place/And we'll not fail" (I.vii.64-5). Here she attempts to convince him that the two of them are in this together, even though he will be the one responsible for the actual killing. This allows...
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