Proton Pump Inhibitors
Proton Pump Inhibitors
Discuss the symptoms for which PPIs are prescribed and the intended target of these drugs.
Typically, the stomach produces acid to kill bacteria (germs) and help digest food by activating certain enzymes. However, the acid is corrosive; therefore, the body has to develop mucous to act as a natural barrier that protects the stomach lining from being eroded. Nevertheless, some individuals have broken mucous enabling the acid to pass through and damage the stomach causing ulcers (Mullin et al. 2009). That may come up with symptoms like a burning pain in the upper abdomen, temporal pain whenever one eats anything, bloating, heartburn, vomit, and dark stool in severe instances.
In other people, there could be a problem with the Sphincter, which usually keeps the stomach tightly closed. Hence, it could result in acid escape into the gullet, causing acid reflux with signs like throat inflammation and heartburn.
Subsequently, the admission of Proton Pump inhibitors would stop the lining cells from secreting more acid. The reduction of acid production can prevent the formation of ulcers and assist in the healing process (Mullin et al., 2009). Moreover, decreasing the...
The way that the inhibitors for the Proton Pump work is that they inhibit the enzyme composed of the hydrogen-potassium and the adenosine triphosphatase composition system in the stomach lining cells. It is responsible for the production of stomach acid.An organelle that would also be affected by these drugs. Based on the function of that organelle, do the issues in the website make biological sense?
A lysosome is one such organelle affected by Proton Pump Inhibitors simply due to...
…reflux disease (Hershcovici & Fass, 2010). Moreover, a positive impact has been reported on the use of Acupuncture in decreasing stomach acid and LES regulation.On the other hand, when one eats a lot of food in the evening, a heavy amount of food remains in the stomach when they sleep, inserting much pressure on the muscular Sphincter. As a result, more acid enters the esophagus. Therefore, to manage acid reflux, one should take heavy meals earlier and light meals in the evening to ensure that everything is digested within an appropriate time (Hershcovici & Fass, 2010). Natural treatment of acid reflux is recommended and biblically supported. For instance, according to Mathew 4:23 (Lijo & Th, 2010), "And Jesus went about all Galilee, teaching in their synagogues, preaching the gospel of the kingdom, and healing all manner of sickness and all manner of…
References
Ballabio, A., & Bonifacino, J. S. (2020). Lysosomes as dynamic regulators of cell and organismal homeostasis. Nature reviews Molecular cell biology, 21(2), 101-118.
Hershcovici, T., & Fass, R. (2010). Management of gastroesophageal reflux disease that does not respond well to proton pump inhibitors. Current opinion in gastroenterology, 26(4), 367-378.
Lijo, D., & Th, M. Introduction to the Public Ministry of Jesus: An Exegetical Study of Matthew 4: 17-25.
Liu, W., Baker, S. S., Trinidad, J., Burlingame, A. L., Baker, R. D., Forte, J. G., ... & Zhu, L. (2013). Inhibition of lysosomal enzyme activities by proton pump inhibitors. Journal of gastroenterology, 48(12), 1343-1352.
Mullin, J. M., Gabello, M., Murray, L. J., Farrell, C. P., Bellows, J., Wolov, K. R., ... & Thornton, J. J. (2009). Proton pump inhibitors: actions and reactions. Drug discovery today, 14(13-14), 647-660.
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