Relationship between Addiction, Insomnia, and Locked-in syndrome

Peer Responses
Peer 1 Tara
I found the discussion on serotonin and the thalamus to be interesting. What is your take on the way addiction impacts the brain and the body’s need to feel good? Does this affect one’s natural ability to unwind, relieve stress, or fall asleep? I myself would like to study this area more in detail because I am interested in understanding how addiction can worsen or spiral into even deeper troubles as the body becomes more and more dependent on a certain feeling. I think a lot of it has to do with simply not being able to rest the mind, relax and sleep. People chase oblivious states, which is like a substitute for good, healthy sleep. They do not have the capacity or ability to engage in sleep because they are missing something. I would like to see if healthy eating and exercise in the outdoors would have a big impact on mediating the effects of addiction on insomnia. Have you come across any instances of this? This one by Younes et al. (2016) looks interesting. I might also recommend the study by Kandeger, Selvi and Tanyer (2019).
References
Kandeger, A., Selvi, Y., & Tanyer, D. K. (2019). The effects of individual circadian rhythm differences on insomnia, impulsivity, and food addiction. Eating and Weight Disorders-Studies on Anorexia, Bulimia and Obesity, 24(1), 47-55.
Younes, F., Halawi, G., Jabbour, H., El Osta, N., Karam, L., Hajj, A., & Rabbaa Khabbaz, L. (2016). Internet addiction and relationships with insomnia, anxiety, depression, stress and self-esteem in university students: A cross-sectional designed study. PloS one, 11(9), e0161126.
Peer 2 Marci
Locked-in syndrome is an interesting disorder, and any injury to the brain can be traumatic to the body, as you point out. The devastation caused to the pons is important to consider and the fact that few people with this regain their motor skills suggest that the brain is somewhat fragile in terms of rehabilitation. However, I wonder if there is not some type of focus that can be made to help the brain to overcome these issues of degeneration and shutdown. It the person’s eyes and awareness are functioning, it should be worth trying. But how does one know the person is aware? I would be interested in reading more up on this particular issue because it sounds fascinating. Of course when I search for articles, I come up with a different type of lockdown syndrome—one related to COVID 19 lockdowns (Choudhery & Ansari, 2020; Garnero et al., 2020). That also is something I think should be researched because not enough attention is being given to it!
References
Choudhery, A. A., & Ansari, T. (2020). LOCKDOWN SYNDROME VS COVID-19 IN INDIA. European Journal of Biomedical, 7(8), 382-385.
Garnero, M., Del Sette, M., Assini, A., Beronio, A., Capello, E., Cabona, C., ... & Pesce, G. (2020). COVID-19-related and not related Guillain-Barré syndromes share the same management pitfalls during lock down: The experience of Liguria region in Italy. Journal of the Neurological Sciences, 418, 117114.