emedicine.com,2004). It is possible that a small number of infants that are diagnosed with TOF may also have other ventricular septal defects or an abnormality in the way that the coronary arteries branch. Some also have a complete obstruction from the right ventricle, getting no flow from there at all. Usually, the flow of blood to the lungs is quite limited by the condition, as well. When the flow of blood to the lungs is found to be restricted, the combination of having an overriding aorta and the ventricular septal defect allows blood that is poor in oxygen to return to the right atrium and right ventricle, where it is then pumped out to the rest of the body, instead of the oxygen-rich blood that the body needs and should be receiving. This shunting can cause babies to look very blue and this occurs because the blood that is low on oxygen has a darker color, which can make the lips and skin appear to have a bluish cast to them. How serious this bluing, or cyanosis, is depends on the severity of the narrowing of both the right ventricular outflow tract and the pulmonary valve. The...
Tetralogy of Fallot: Literature Review Tetralogy of Fallot is a congenital heart defect associated with systemic cyanosis, accounting for approximately 5 to 6% of all cases of congenital heart disease and is characterized by; ventricular septal defect, aortic override, pulmonary stenosis and right ventricular hypertrophy. It is the most common cause of blue baby syndrome with children diagnosed developing Tet spells. Sudden increases in cyanosis followed by syncope characterize Tet spells
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