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It is easily absorbed through the digestive tract and is therefore almost always administered orally; the substance can also be absorbed through the skin, so gloves would be worn when handling large quantities of warfarin sodium (WHO 1995). Warfarin works in the body to disrupt Vitamin K's role in synthesizing certain blood clotting factors, and for ths reason levels of Vitamin K ingestion must be monitored to ensure safe blood clotting times without reduced effectiveness (Newcomer 2003).
Patient Info and FAQ Site
Bristol-Myers Squibb Company, the manufacturer of the Coumadin brand name, operates a website at coumdin.com that provides a basic overview of the drugs use, dosages, possible side effects and dangers, and frequently asked questions (BMSC 2008). As the information here necessarily comes form a biased source, verifying its claims and conclusions on a site such as drugs.com -- which answers to its advertisers, admittedly, but which trades on its reliability and therefore has a larger stake in providing objective information -- is a wise decisions. The information here is largely the same, but it is somewhat more imply presented and far more trustworthy (Drugs.com 2009). They do not provide a frequently asked questions resource for this...
Gradually, human beings have learned to take the potential evils they find in nature and turned them to more productive and even life saving uses. This is precisely the path that was taken with warfarin sodium, which began as a cattle killer and ended up saving the life of a U.S. President and countless other individuals the world over. There is no telling what tomorrow's miracle drug will be, but it is very possible that it, too, will be discovered by accident.
References
Bristol-Myers Squibb Company. (2008). "Coumadin." Accessed 2 October 2009. http://www.coumadin.com/for_hcp.aspx
Drugs.com. (2009). "Coumadin." Accessed 2 October 2009. http://www.drugs.com/coumadin.html
Newcomer, J. (2003). "A Short History and Useful Factoids about Warfarin (Coumadin)." Flounder. Accessed 2 October 2009. http://www.flounder.com/warfarin.htm
WHO. (1995). "International Programme n Chemical Safety: Warfarin." Accessed 2 October 2009. http://www.inchem.org/documents/hsg/hsg/hsg096.htm#PartNumber:6
Echocardiogram is another important non-invasive diagnostic tool for AF. This test uses sound waves to produces an image of the heart and helps the cardiologist observe the different regions of the heart and assess their performance. [NIH] Treatment for AF involves different approaches and may also be decided by the cardiologist depending on the nature of the AF. Paroxysmal AF, which lasts for a short duration (maximum few days) is
After ICI discharge daily ECG or predischarge (Jansen et al., 1986; Evrard et al., 2000) Holter monitoring was used to detect arrhythmias. In some cases the monitoring may be continued beyond the hospital stay for 30 (Guarnieri et al., 1999) up to 90 days (Weber et al., 1990). The use of the Holter monitor makes extended monitoring more feasible than when ECG was the only option. Several anomalies have been
Atrial Fibrillation Simply stated, atrial fibrillation describes a condition in which the human heart beats at an excessively rapid rate that can result in diminished blood flow to the body. While the condition is not typically life-threatening, atrial fibrillation still requires immediate medical care because left untreated, the condition can result in adverse, long-term complications. To determine the facts, this paper reviews the relevant literature concerning the etiology and pathogenesis
Lessening the Incidence of Postoperative Atrial Fibrillation The issue of reducing or preventing atrial fibrillation (AF) after cardiac surgery has been the subject of numerous studies. Existing studies sought to establish which agents are effective in this process since multiple agents are used to prevent AF. Reduction of incidence of postoperative atrial fibrillation is critical in order to promote the outcomes of patients undergoing cardiac surgery. In addition to flutter, atrial
Nursing Diagnosis Care Plan Assessment Data Analysis a) Patient is a 65-year-old male Mexican-born retired bus driver with a relevant past medical history of atrial fibrillation and deep vein thrombosis treated with Coumadin who presents with hematuria. Patient sought care after witnessing blood in his urine and feeling generally weak. In addition, the patient has history of hypertension, stroke, DVT, BPH, gout, depression, anxiety, chronic bronchitis and a remote history of chicken
Efficacy and Safety of Dabigatran vs. Warfarin for Stroke After more than five decades as the preferred anticoagulant worldwide, warfarin is being challenged by a new rival that doesn't require careful dosage monitoring. Pradaxa (dabigatran) was unanimously approved by the FDA on October 19, 2010 for treating atrial fibrillation (AF) patients, who are at an increased risk for suffering stroke and systemic embolisms (U.S. Food and Drug Administration). Dabigatran acts by