- Words: 1553
- Length: 5 Pages
- Topic: Genetics
- Paper #: 74612288
Altogether, the Icelandic findings implicate epigenetic silencing of the BRCA1 gene in sporadic breast tumors. They even suggest that "the BRCA1 gene is implicated in sporadic breast tumorigenesis through epigenetic silencing and deletion of the BRCA1 gene," and that BRCA1 methylation is also found to be important in hereditary breast cancer, indicating similarities between BRCA1 methylated and hereditary BRCA1 breast tumors (Birgisdotter, et al. 9).
While heredity factors strongly contribute