Why Obesity Is so Difficult to Treat

Obesity

Why Obesity is so Difficult to Treat

Determination of obesity

Proper definition of obesity

Obesity in perspective of the World Health Organization (WHO)

Historical trends

Health and Economic Costs

Prevalence and Time Trends

Prevalence of obesity among men

Prevalence of obesity among women

Prevalence of obesity among children

Demographic Variations in Overweight and Obesity Prevalence

Economic Costs of Overweight and Obesity (The Evidence Report,1998)

The world market for treating obesity

Causes of obesity

Continuous availability of high-energy foods

a) Imbalance calorie intake and BMR requirements (Gayle M. Galletta)

b) Craze of consumption of unhealthy food

c) Quick life style and less determination of hunger satisfaction

d) Other factors associate with weight gain

Way of eating

Unintentionally over eating

Less planning to make and eat healthy meals (A.D.A.M. Medical Encyclopedia, 2012)

Major reduction in the obligatory need for physical activity (Joseph Proietto, 2011)

a) Spending long hours in front of TVs and computers doing work

b) Relying on cars instead of walking

c) Modern technology and fewer physical demands at home

d) Lack of physical education classes in schools

e) Lack of doing other leisure physical activities.

3. Failed medicinal development for the treatment of obesity

a) Cases of medicinal failure before U.S. Food and Drug Administration (FDA)for treating obesity

i. Wyeth's case of medicinal failure

ii. Sanofi-Aventis case of medicinal failure iii. AU.S. organization's case of medicinal failure

iv. Abbot Company's case of medicinal failure

v. Reductil case of medicinal failure

b) Cases of medicinal failure after U.S. Food and Drug Administration (FDA)for treating obesity

i. Cases of Vivus' Qnexa failure

ii. Cases of Topiramate and Phentermine failure iii. Cases of Contrave failure

iv. Cases of Bupropion failure

c) Aspects of anti-obesity medicinal failure to penetrate into the respective markets

i. First aspect: the awareness of obesity

Role of anti-obesity drugs and their side effects

ii. Second aspect: a unique nature of obesity

Role of traditional obesity treatments and their neurological side effects

d) Outcomes of medicinal development for the treatment of obesity

5-Treatment Guidelines

A. Overview

B. Assessment and Classification of Overweight and Obesity

Assessment of Overweight and Obesity

Classification of Overweight and Obesity

Assessment of Risk Status

Evaluation and Treatment Strategy

Exclusion from Weight Loss Therapy