Gene Therapy Essays (Examples)

Filter results by:

 

View Full Essay

Sickle Gene Therapies for Sickle

Words: 1128 Length: 4 Pages Document Type: Essay Paper #: 95693355

Implications for ongoing research into genetic therapies and side effects/later developments are discussed at length.

Yannaki, E. & Stamatoyannopoulos, G. (2010). Hematopoietic stem cell mobilization strategies for gene therapy of beta thalassemia and sickle cell disease. Annals of the New York Academy of Sciences 1202: 59-63.

Though the clinical trial these two researchers are involved in does not yet have results that are ready for publication, the review of the risks they provide regarding the use of stem cell mobilization with G-CSF in patients with sickle cell is highly useful information. So, too, is the practice of pre-treating patients with hydroxyurea before administering the stem cell treatment, which the authors describe in detail and which forms the basis of the related clinical trial. Potential reduction of risks appears to be quite promising, though final results from the clinical trial and other supporting evidence will of course be required.

Ye, L.,…… [Read More]

View Full Essay

Gene Technology

Words: 1232 Length: 4 Pages Document Type: Essay Paper #: 32580332

Gene Technology

Genetically Modified Crop Plants

The term genetically modified organisms, popularly referred to as GMOs, constitute crops, animals and even microorganisms that have undergone development my man and technology. Through the great leaps man has developed in technology, it is now possible to 'create' organisms and plants through the combination of genes considered superior, resistant and quick-maturing. Farming and animal rearing land brings a challenge in the current world, due to population explosions. This trend has been brought about by the necessity to feed the ever-increasing food demand by world populations.

The world today carries over six billion people, a number that increases every day. The natural means of plant reproduction cannot support to feed this population due to the long time taken to grow to maturity, poor yields and the limited space for planting. Therefore, genetic modification has gained an edge in the development of such crops as…… [Read More]

References

Conway, G. 2000. Genetically modified crops: risks and promise. Conservation Ecology 4(1): 2. [online] URL: http://www.consecol.org/vol4/iss1/art2

McMichael, D. Costanza, R., H. Daly, C. Folke, P. Hawken, C.S. Holling, A.J. Pimentel, and D. Rapport. (2000). Managing our environmental portfolio. Bioscience 50: 149-155.

Deborah B. Whitman (2000) Genetically Modified Foods: Harmful or Helpful? (Released April 2000) http://www.csa.com/discoveryguides/gmfood/overview.php

Ellstrand, N. 2000. The elephant that is biotechnology: Comments on "Genetically modified crops: risks and promise" by Gordon Conway. Conservation Ecology 4(1):8. [online] URL: http://www.consecol.org/vol4/iss1/art8
View Full Essay

Gene Tech Biological Basis Personalized Genomics and

Words: 1095 Length: 4 Pages Document Type: Essay Paper #: 5682887

Gene Tech

Biological Basis

Personalized genomics and personalized medicine refers to a collection of technologies and techniques designed to custom design pharmaceutical treatments according to the patient's genome sequence. The starting point for personalized medicine, which has also been called "stratified medicine" or "precision medicine" is the completion of the Human Genome Project (NHMC, 2014). The Human Genome Project has permitted unprecedented access to genetic information and the implications the information has on human health factors.

A genome is the entire collection of genes, about 23,000 different ones, embedded in each cell of the body (The Jackson Laboratory, 2014). According to Snyder, Du & Gerstein (2010), determining a genome sequence involves "identifying single-nucleotide polymorphisms [SNPs] and structural variations [SVs], assembling new sequences, and phasing haplotypes," (p. 423). Although only two percent of the human genome is actually comprised of genes themselves, the human genome "influences how we look, our genetic…… [Read More]

References

The Jackson Laboratory (2014). Personalized medicine and genomics. Retrieved online: http://www.jax.org/ct/genomics.html

"Personalized Medicine," (n.d.). U.S. News and World Report. Retrieved online: http://health.usnews.com/health-conditions/cancer/personalized-medicine/overview

National Health and Medical Research Council (NHMRC, 2014). Personalized medicine and genetics. Australian Government. Retrieved online: https://www.nhmrc.gov.au/your-health/genetics-and-human-health/genetic-testing-and-applications/personalised-medicine

Snyder, M., Du, Jiang & Gerstein, M. (2010). Personal genome sequencing: current approaches and challenges. Genes and Development 2010(24), 423-431.
View Full Essay

Physical Life Science Genes Are

Words: 698 Length: 2 Pages Document Type: Essay Paper #: 53783681

During the gene decoding process the double stranded DNA splits up to reveal a single strand from which the base sequence of the gene is copied onto a single stranded nucleic acid known as the messenger ribonucleic acid or mRNA. This implies that we have an exact copy of the gene base in the mRNA except that Urasil (U) replaces the T. base and deoxyribose is replaced by ribose. Translation on the other hand is the actual process of protein synthesis from the mRNA strands. Ribosomes work with the mRNA for protein synthesis within the cells. [the State University of New York]

4) Mutation, Gene Migration, Genetic Drift, Non-random Mating and Natural Selection are the five processes that can affect the frequency of genes in a population. [CMGS]

5) Kindom Protista is considered to be the ancestor of all eukaryotic kingdoms and includes algae, plant like, animal like and fungus…… [Read More]

Bibliography

Cherie Dimaline, "Inheriting Sickness When Finding Your Roots is a Matter of Life or Death" Accessed on 15th December 2004, http://www.metisnation.org/metisVOYAGEUR/MVcurrent/disease.html

Dr. Joseph F. Smith, "Genetic Counseling," Accessed on 15th December 2004, http://www.chclibrary.org/micromed/00049280.html

IBAC, "The Basics of Life," Accessed on 15th December 2004, http://www.ibac.org.nz/booklet/basics.html

CMGS, "Disturbance of Gene Frequencies in a Population," Accessed on 15th December 2004 http://www.ich.ucl.ac.uk/cmgs/genefreq.htm
View Full Essay

Gene Technology

Words: 976 Length: 3 Pages Document Type: Essay Paper #: 72972058

Genetically Modified Foods: ational for Topic Selection

Genetically modified foods are frequently in the mainstream media, making them a highly relevant topic of discussion in the areas of genetic science and gene technologies. As with most technologies and techniques related to genetic science, genetically modified foods are controversial and thus politically charged issues. It is important to be armed with facts before forming an opinion about whether or not genetically modified foods are acceptable, feasible, or ethical.

Biological Basis

Genetically modified foods refers to organic foodstuffs -- plants and animals -- "whose genetic material (DNA) has been modified in a way that does not occur naturally," (World Health Organization, 2013). However, genetically modified organisms (GMOs) can also include medicines and vaccines (United States Department of Energy: Office of Science, 2013). The primary process used to modify the genes of organisms is called recombitant DNA technology; as the term suggests, recombitant…… [Read More]

References

Damery, P., D'Adamo, N., Graham, M., Hoffman, M. & Riedl, J. (n.d.). The debate on labeling genetically modified food. Retrieved online:  http://www.public.iastate.edu/~ethics/LabelGMFood.pdf 

"Genetically modified crops gaining ground in China: Report," (2013). The Times of India. 7 March, 2013. Retrieved online:  http://timesofindia.indiatimes.com/home/environment/developmental-issues/Genetically-modified-crops-gaining-ground-in-China-Report/articleshow/18847379.cms 

Hiatt, S. & Park, S. (2012). Influence and regulatory approval of genetically modified organisms. Academy of Management Journal. Nov 26, 2012.

United States Department of Energy: Office of Science (2013). Human genome project. Retrieved online: http://www.ornl.gov/sci/techresources/Human_Genome/elsi/gmfood.shtml
View Full Essay

Expanding the Traditional Definition of a Gene Through Epigenetics

Words: 1301 Length: 4 Pages Document Type: Essay Paper #: 8617150

Expanding Traditional Definition of a Gene

Expands Traditional Definition A Gene

Expanding the traditional definition of a gene through epigenetics:

Changes to the human gene through exposure to external forces in the environment

Increasingly, the field of epigenetics is challenging traditional conceptions of what constitutes the human gene. While it has long been acknowledged that parents can pass their DNA onto their offspring, epigenetics acknowledges the potential for changes in human DNA which subsequently causes a change in the genetic composition of the child. Epigenetics acknowledges "the external environment's effects upon genes can influence disease, and some of these effects can be inherited in humans" (Simmons 2008). While it is difficult to design a study to test environmental factors, historical and experimental research does support this hypothesis. "For example, Swedish scientists recently conducted investigations examining whether nutrition affected the death rate associated with cardiovascular disease and diabetes and whether these…… [Read More]

References

Egger, G. (et al. 2004) Epigenetics in human disease and prospects for epigenetic therapy. Nature 429, 457 -- 463. Retrieved from:  http://www.nature.com/scitable/content/Epigenetics-in-human-disease-and-prospects-for-13630 

Roseboom, T. (et al. 2001). Effects of prenatal exposure to the Dutch famine on adult disease in later life: an overview. Molecular and Cellular Endocrinology 185 (2001) 93 -- 98.

Retrieved from:   http://www.nature.com/scitable/topicpage/epigenetic-influences-and-disease-895  

Herrera, B. (et al. 2011). Genetics and epigenetics of obesity. Maturitas, 69(1): 41 -- 49.
View Full Essay

Reality and Feminist Therapy Order

Words: 761 Length: 2 Pages Document Type: Essay Paper #: 28642336

"Briefly, feminists believe the personal is political. Basic tenets of feminism include a belief in the equal worth of all human beings, recognition that each individual's personal experiences and situations are reflective of and an influence on society's institutionalized attitudes and values, and a commitment to political and social change that equalizes power among people. Feminists are committed to recognizing and reducing the pervasive influences and insidious effects of oppressive societal attitudes and society" (Chappell 2000). In its current incarnation, feminist therapy's stress upon liberating individuals from oppressive social attitudes does not just pertain only to gender, but all negative social attitudes. Thus, at its most universal, feminist therapy's central tenant that the personal and political are intermeshed, and that one's political reality creates one's cognitive reality, can be applied to many contexts beyond gender.

Although it deals with the psychology created by oppression, feminist therapy still stresses personal choice…… [Read More]

Works Cited

Chappell, Marcia. (2000). Feminist therapy code of ethics. Feminist Therapy Institute.

Retrieved August 14, 2009 at http://www.feminist-therapy-institute.org/ethics.htm

Reality therapy. (2008). International Journal of Reality Therapy.

Retrieved August 14, 2009 at http://www.journalofrealitytherapy.com/realitytherapy.htm
View Full Essay

Application of Personality Theories to Counseling and Therapy

Words: 2507 Length: 7 Pages Document Type: Essay Paper #: 86383313

Personality Therapy

Personality is very complex. Individuals can differ considerably from one another, because of the wide variety of traits possible. In addition, a person can act a certain way in one situation and completely different in another, or have internal processes that manifest themselves through very different external actions and behaviors. Because of this diversity and complexity, psychologists have developed a number of theories to explain personality phenomena, as well as suggest yet unknown possibilities. This report, based on the book Perspectives on Personality by Charles Carver will discuss these theories and how they can be applied for behavioral change through therapy.

Two theories fall under the dispositional perspectives category, which emphasize that people display consistency or continuity in their actions, thoughts and feelings: The "trait and type" theory and the "needs and motives" theory. The first concludes that people can be divided into different types or categories. Nomothetic…… [Read More]

View Full Essay

Schizophrenia and Genetics These Three Genes Offer Some Clue

Words: 2024 Length: 8 Pages Document Type: Essay Paper #: 84771633

Candidate Genes for Schizophrenia

Their Impact on Neuro-development

Search Improvement over Published Methodology

rief Introduction -- Schizophrenia is a mental disorder, which is characterized by delusions, lack of drive and interest, changed or unusual emotional reactions and generally disorganized behavior (Kirov et al. 2012). Some signs may begin from childhood but main features become apparent in the late teens and early adulthood. Outcomes and treatment are varied but relapses are frequent. Remissions are also often only partial along with significantly reduced social and occupation involvement. Persons with this disorder are among the most vulnerable, ostracized, and thus disadvantaged in society. A recent meta-analysis reported that about 15.2 out of every 100,000 persons are afflicted with it (Kirov et al.).

Genetic epidemiological studies theorize that varied susceptibility to schizophrenia appears to be strongly genetic (Kirov et al. 2012). These studies have identified many potentials links between genes and chromosomal abnormalities. Increasing…… [Read More]

BIBLIOGRAPHY

Brian, I. P. et al. 2005. 'Techniques for the identification of genes involved in psychiatric

disorders', Vol. 39, Australian and New Zealand Journal of Psychiatry

Hamshere, M. L. et al. 2012. 'Genome-wide significant association in schizophrenia to ITIH3/4,

CACNA1C and SDCCAG8 and extensive replication of associations reported by Schizophrenia PGC', Molecular Psychiatry, [Online] Available at http://www.ncbi.nlm.nih.gov/pubmed/22614287
View Full Essay

Genetic Pathway of Breast Cancer

Words: 2282 Length: 8 Pages Document Type: Essay Paper #: 53395187

, 2006). He visualized and described the malignancy process. He suggested that early that "cells of tumors with unlimited growth" would develop with the elimination of chromosomes, which inhibit the growth. The multiple genetic alterations in these inhibiting chromosomes are today known as TSGs. The theory supposes that cancer arises from functional defect or absence of one or more TSGs. Clinical trials of TSG gene replacement therapy for breast cancer include the viral wild-type p53, Rb, and mda7. Molecular chemotherapy involves the introduction of suicide genes. The concept evolved from the assumption that cancer cells could be made more sensitive to chemotherapeutics or toxins by introducing "suicide genes." It was a concept initiated in the late 80s. Suicide gene therapy is categorized into toxin gene therapy and enzyme-activating pro-drug therapy. Suicide gene therapy is also called gene-directed enzyme pro-drug therapy or GDEPT. GDEPT treatment consists of the delivery of the…… [Read More]

BIBLIOGRAPHY

Abaan, O. D and Criss, Wayne E (2002). Gene therapy in human breast cancer. 32

(2002): 283-291 Turkey Journal of Medical Science: Tubitak. Retrieved on April 15,

2010 from http://journals.tubitak.gov.tr/medical/issues/sag-02-32-4-1-0204.pdf

Lowery, A.J., et al. (2009). MicroRNA signatures predict oestrogen receptor,
View Full Essay

Oncology Nurse the Maxim 'Prevention

Words: 850 Length: 3 Pages Document Type: Essay Paper #: 1995504

[Paula Trahan, 450]

Genetic Nurse and Genetic research

Asides these important aspects of care giving for a cancer patient, an oncology nurse is now also involved in the proactive approach of screening for potential cancer patients. Since the successful mapping of the human genome and the identification of genetic components that cause the onset of cancer, oncology nurses have taken on a new and important role in preventive diagnostics. They gather family history, construct pedigree and interpret them based on the genetic predisposition to cancer. The oncology nurse also offers counseling service to people thus identified to be at risk. Thus there is an emergence of the oncology nurse as a genetic service provider. oth the international Society of Nurses in Genetics (ISONG) and the ANA (American Nurses Association) have already formulated credentialing standards for genetic nurses keeping in view the quality concerns in this new and evolving role of…… [Read More]

Bibliography

Michele Gaguski, MSN, RN, (Aug 2006) 'Oncology nurses play a pivotal role in cancer prevention', ONS vol 21, No 8

Paula Trahan Rieger (April 2001), 'The role of oncology nurses in gene therapy'

The Lancet Oncology - Volume 2 Issue

Connie Henke Yarbro, Margaret Hansen & Michelle Goodman, (2005) "Cancer Nursing: Principles and Practices," Jones and Bartlett Publishers, Sixth edition
View Full Essay

Krabbe Disease

Words: 1378 Length: 4 Pages Document Type: Essay Paper #: 90314131

Krabbe Disease

Genetic Components of the Disease

Metabolic Components of the Disease

Causes of the disease

Symptoms of the disease

Diagnosis of the disease

Treatment of the disease

Cord lood Transfusion

Treatment for Late on-set Form

Gene Therapy

Incidence and Longevity of the disease

Socioeconomic Factors

Krabbe disease, also referred as globoid cell leukodystrophy (GLD), causes a deficiency in galactocerebrosidase (GALC), the enzyme responsible for preventing a build-up of galactolipids in the brain. Without the regulation of galactolipids, the growth of the myelin sheath around the nerve cells is severely impaired. Krabbe disease usually presents in first 6 months of the life. A child in the last stages of Krabbe disease is immobilized and has decreased level of responsiveness. Most of them die at the age of 2. (Lantos, 2011)

Genetic Components of the Disease

GLD is one of the subgroup of metabolic disorders called leukodystrophies. The leukodystrophies are caused…… [Read More]

Bibliography

(2011). The Case of Krabbe Disease. In J. Lantos, Dangerous and Expensive Screening and Treatment for Rare Childhood Diseases. Kansas City, Missouri.

Mayo Clinic Staff. (2011, June). Mayo Clinic. Retrieved March 2013, from Krabbe Disease: http://www.mayoclinic.com/health/krabbe-disease/DS00937/DSECTION=risk-factors

Orchard, P. (2013). National Marrow Donor Program. Krabbe Disease.

Rosenberg, R.N. (2008). The Molecular and Genetic Basis of Neurologic and Psychiatric Disease. Lippincott Williams & Wilkins.
View Full Essay

Genome Sequencing and Comparative Genomics

Words: 2012 Length: 8 Pages Document Type: Essay Paper #: 94040147

Genomes and Comparative Genomics

Over the last decade we have achieved rapid strides in the field of genetic engineering. The study of molecular biology has been fairly advanced mainly aided by the unprecedented growth in information technology. Today bio-informatics has opened new vitas for us and we are already progressing in investigating and in the comparative study of genomes. This has shed new light up on our knowledge of the evolutionary process and the important concepts such as protein folding and selective expression, which have so far eluded our understanding, are beginning to unfold. Let us have a brief overlook of the subject.

The Role of DNA

One of the greatest achievements of the twentieth century has been the unraveling of the mysteries behind the DNA and the mechanism of protein synthesis. Genes are the fundamental units of biological inheritance and are made up of Deoxyribonucleic acid (DNA). Genes are…… [Read More]

Bibliography

Mullis, KB (1990), Scientific American, April 1990, 56

Hecht, J., 19 May 2003, Chimps are human, gene study implies, New Scientist

Cohlan, A., 30 May 2002, "Just 2,5% of DNA turns mice into men," New Scientist

TK Attwood & DJ Parry Smith, "Introduction to bio Informatics," Published by ADDison Wesley Longman Ltd., 1999
View Full Essay

Technology Has Revolutionized Society Communication Transportation Commerce

Words: 1736 Length: 4 Pages Document Type: Essay Paper #: 84215378

technology has revolutionized society: communication, transportation, commerce, and especially medicine. . Ironically, for centuries and still in Oriental Medicine, healthcare was and is tailored to the individual. Even the Greek Physician Hippocrates wrote that he prescribed sweet elixirs to some and astringents to others depending on their individual condition (Pray, 2008). 21st century medicine, though, is more about an individual person's genetic code, and is made possible by advances in genetic technology and engineering. This is partially due to the Human Genome Project, a massive program completed in 2003 that focused on the identification of the individual genes that make up human DNA with the overall hope that it would initiate genomic medicine -- healthcare delivered based on the individual's medical history and genetic profile (About the Human Genome Project, 2011). Traditionally, medicine diagnoses human illnesses based on quantitative and qualitative signs and symptoms. With the advent of genetic technology,…… [Read More]

References

About the Human Genome Project. (2011, September 19). Human Genome Management Information Systems. Retrieved from: http://www.ornl.gov/sci/techresources / Human_Genome/project/about.shtml

Gattaca. (1997, March). Retrieved from International Movie Database:  http://www.imdb.com/title/tt0119177/ 

Personalized Medicine - An Overview. (2011, January 11). Retrieved from: U.S. News Health report: http://health.usnews.com/health-conditions/cancer/personalized-medicine

Public Law 110-223. (2008). The Genetic Information Nondiscrimination Act of 2008. Retrieved from: http://www.gpo.gov/fdsys/pkg/PLAW-110publ233/content-detail.html
View Full Essay

Philosophy the Murder-Cannabalism of Bernd

Words: 1953 Length: 5 Pages Document Type: Essay Paper #: 6521115



Question 5:

Since the events of September 11th, terrorism has been a crucial concern for Americans specifically, and the global society in general.

As Wilkins (2005) notes, although it is generally agreed to be justifiable to commit violence in the act of self-defense against aggressors, many of the victims of terrorism are innocent of any crime, and that the question of "collective guilt" must come into play when determining the justification for terrorism. There is a "distinction between moral guilt and metaphysical guilt (which) can be explained partially in terms of the difference between the failure to do one's duty and the failure to perform a supererogatory act. We have a duty to mutla aid to other human beings" (p. 340).

Therefore, it is justifiable to inflict violence upon innocent individuals when this guilt is apparent, such as the case of the plight of the Jews and the aggression of…… [Read More]

References

An-Na'im, A.A. "Islam, Islamic Law." Applied Ethics: A Multicultural Approach. Ed. May, L., Collins-Chobanian, S., & Wong, K. Upper Saddle River, NJ: Prentice Hall, 2005. pp. 101-108.

Bolte, A. "Do Wedding Dresses Come in Lavender? The Prospects and Implications of Same-Sex Marriage?" Applied Ethics: A Multicultural Approach. Ed. May, L., Collins-Chobanian, S., & Wong, K. Upper Saddle River, NJ: Prentice Hall, 2005. pp. 399-410.

Goering, S. "Gene Therapies and the Pursuit of a Better Human." Applied Ethics: A Multicultural Approach. Ed. May, L., Collins-Chobanian, S., & Wong, K. Upper Saddle River, NJ: Prentice Hall, 2005. pp. 659-668.

Leth, F. "Confessed Cannibal Given 8.5-Year Prison Sentence." Title of Source. Day Month Year: pages.
View Full Essay

Future of DNA Testing the

Words: 2054 Length: 7 Pages Document Type: Essay Paper #: 11879003

The scientists ran the DNA computer only in a test tube. They foresaw the need for an injectable version for intracellular activities, which could take decades to devise.7

In response to the fear of nonscale robots going around inside the body, the scientists said they placed safeguards into their systems.7 When more reliable DNA computers are invented with fewer mistakes, people could become more comfortable with injectable robots and accept them, the scientists said.7

A Milestone in Dental Science

OralDNA Labs, Inc., a specialty diagnostics company, provides science-based

Diagnosticand prognostic lab tests to target periodontal disease.8 Periodontal disease afflicts a quarter of the adult U.S. population. Neglect does not only result in serious gum disease and tooth loss. It has also been linked with diabetes and cardiovascular disease. The company introduced MyPerioPathsm and MyPerioIDsm DNA tests. MyPerioPathsm identifies the presence of bacteria. MyPerioIDsm determines susceptibility to periodontal disease. The combination…… [Read More]

REFERENCES

1. Saad R. Discovery, development and current applications of DNA identity testing. Baylor University Center. April 2005

2. Connor S. Let us rid society of genetic defects, says DNA pioneer. The (London) Independent. April 16, 2001

3. Eakins P. Strides foreseen in genetic research. Topeka Capital-Journal. May 6, 2000

4. Pw. Designer kids, super-athletes and genomic cures. Whole Earth. Summer 2000
View Full Essay

Cogito Ergo Sum as Stated

Words: 1796 Length: 5 Pages Document Type: Essay Paper #: 51847710

As such, every human being has 70,000 pairs of these genes or instructions that tell the body what to be and how to behave. They have garnered the name "designer" not so much as to pre-selection but more toward blueprint. Although biotechnological development might well be able to "design" a fetus to have all the characteristics that parents want in a child, the more scientific approach is one of natural development in the genes patterning. Not with standing naturalism there are efforts underway to alter some of the 70,000 pairs of genes to cure diseases and prevent defective inherited characteristics. Wherein the debate turns philosophical, ethical, and righteous is on an entire different level however. When reality is present that babies can be genetically engineered to be smarter, better looking, more athletic, and happier the face of human evolution will have changed forever. The lingering question facing citizenry is how…… [Read More]

References

Andrews, Lori B (1999). The Clone Age: Adventures in the New

World of Reproductive Technology. New York, Henry Holt and Company.

Descartes, Rene. Discourse on the Method of Rightly Conducting the Reason, and Seeking Truth in the Sciences. 2 June. 2004 Retrieved Dec. 22, 2004 at http://www.literature.org/authors/descartes-rene/reason-discourse/

Dorland's Illustrated Medical Dictionary, (2000). 29th Edition, W.B. Saunders Company,
View Full Essay

Adoptive Antigen-Specific Immunotherapy Manuscript Review

Words: 916 Length: 3 Pages Document Type: Essay Paper #: 21304671



The current protocols of T cell transduction involve in vitro activation to achieve T cell proliferation that is required for effective retroviral infection. Adoptive transfer of such minimally stimulated cells will reveal whether in vivo transfer of TC transduced resting T cells provides more effective protection from disease and better memory development than transfer of fully activated T cells.

TC gene transfer can also be used to produce antigen-specific CD4+ helper T cells. The in vivo interaction of conventional CD4+ T cells is restricted to MHC class II-positive professional antigen-presenting cells. ecognition of DC presented antigen triggers the production of cytokines by conventional CD4+ T cells. IL-2 has a direct effect on the CD4+ T cells and triggers proliferation and can prevent anergy induction. Other cytokines, such as IFN-, can activate macrophages and natural killer (NK) cells and enhance the functional activity of CTL. In addition, IFN- can have antitumor…… [Read More]

Reference

Xue, S., Gillmore, R., Downs, a., Tsallios, a., Holler, a., Gao, L., et al. (2005). Exploiting T cell receptor genes for cancer immunotherapy. Clin Exp Immunol, 139(2), 167-172.
View Full Essay

Human Stem Cell Medical -

Words: 4660 Length: 17 Pages Document Type: Essay Paper #: 11610140

This bill was sent to the U.S. Senate and set for vote mirroring a bill previously passed by the House during the Summer of 2003 which failed to pass the Senate because of vehement disagreement that was even "within the parties over the prohibition of therapeutic cloning.(National Legislation Concerning Human and Reproductive Cloning, 2004; paraphrased) As of the date of the report on legislation eight U.S. states had passed laws that explicitly prohibited reproductive cloning using human embryos and another five U.S. states have placed a prohibition on cloning for any purpose whatsoever with 22 other U.S. states introducing bills outlawing the reproductive cloning of humans. (Ibid; paraphrased) Patenting laws for genetics allow inventors to patent genetics but only specific genetic factors may be patented and inventors are required to:

1) Identify novel genetic sequences;

2) Specify the sequence's product, 3) Specify how the product functions in nature --i.e. its…… [Read More]

Bibliography

O'Connor, Sean M. (nd) Intellectual Property Rights and Stem Cell Research: Who Owns the Medical Breakthroughs?

Kadereit, Suzanne & Hines, Pamela J. (nd) Overview of Stem Cell Research New England Law Journal 2005 Mar 28. Online available at http://www.nesl.edu/lawrev/vol39/3/13%20Kadereit%20Final.pdf.

Chadwick, Ruth et al. (2004)HUGO Ethics Committee Statement of Stem Cells (2004) November

Legal Protection of Digital Information (2006) Chapter 5: Software-Based Inventions Online available at:.    http://digital-law-online.info/lpdi1.0/treatise63.html
View Full Essay

Prions Proteinaceous Infectious Particles Recent Cases of

Words: 2056 Length: 5 Pages Document Type: Essay Paper #: 79151408

Prions:

Proteinaceous Infectious Particles"

Recent cases of Mad Cow Disease have focused the public attention on prion diseases and the small proteins that are believed to cause them. The scientific community has been slow to recognize this mechanism of disease, since prion-caused encephalopathies can demonstrate diverse symptoms, and share characteristics with other disorders, such as dementia.

Prions, as the acronym (Proteinaceous Infectious Particles) suggests, are small proteins that are typically expressed in brain tissue, and may exist in a normal or abnormal shape. The prion protein is encoded by a gene found on the human chromosome 20. Usually, the prion protein is translated in neural tissue, folds into its normal conformation, carries out its cellular role, and is eventually degraded by enzymes. The abnormal prion, however, folds differently from its normal counterpart. This different shape makes it more difficult to degrade, and leads to the brain damage that is seen…… [Read More]

Bibliography

Inherited prion disease. (n.d.). Retrieved April 21, 2004, at http://www.st- marys.nhs.uk/specialist/prion/factsheets/inheritedpd.htm

Kightly, R. (n.d.). Prion replication and spread at the cellular level. Retrieved April

21, 2004, from Mad Cow Disease Images & BSE Pictures

Web site:  http://www.rkm.com.au/BSE/index.html
View Full Essay

Genome Human Cloning Human Cloning

Words: 3339 Length: 8 Pages Document Type: Essay Paper #: 19327581

(iii) in the United States, Brazil, Germany and France, humans have been receiving their own stem cells to re-grow heart muscle in the unforeseen incident of heart attack or injury. This was found to be successful in majority of the cases. (iv) in one more incident, the vision of 23 patients was restored after limbal adult stem cell transplants. This line of therapeutic care has assisted a lot of people who have been suffering from blindness for years together that includes the sufferers of mustard gas attacks in Iraqi. (Life Issues Institute, 2006) v) Crohn's disease patients have in fact been treated with stem cells evolved from their own blood. (vi) Among the 90% of the 19 patients having several autoimmune disorders like systemic lupus has been on the path to recovery following treatment with their own blood stem cells. (vii) a research of Parkinson's disease displayed an average improvement…… [Read More]

References

AAAS Center for Science, Technology and Congress. (2007) "AAAS Policy Brief: Human

Cloning" Retrieved 28 March, 2008 at http://www.aaas.org/spp/cstc/briefs/cloning/

Barnes, Deborah. (n. d.) "Research in the News: Creating a cloned sheep named Dolly"

Retrieved 28 March, 2008 at http://science-education.nih.gov/home2.nsf/Educational+ResourcesTopicsGenetics/BC5086E34E4DBA0085256CCD006F01CB
View Full Essay

Human Genetic

Words: 417 Length: 1 Pages Document Type: Essay Paper #: 22151116

human genetic. There are four references used for this paper.

There are remarkable advancements being made in the field of genetics. It is important to examine whether the material should be transferred between organisms, as well as the effects on food today.

Genetic Material

Many people wonder if genetic material should be transferred from one organism to another.

hile benefits have been shown in biotechnology, it is important for scientists to utilize technology carefully and wisely, since "any technology has the potential for being abused, and there is the possibility that genetically engineered 'monsters' could be created with the use of recombinant DNA techniques (Phillips)."

Although gene therapy research is increasing, in a majority of cases it is still too ineffective to be beneficial. Humans should not compete with or alter nature since "gene therapy alters an individual's genetic blueprint, which in time could lead to 'selective breeding' (unknown)."

Biotechnology…… [Read More]

Works Cited

Conko, Gregory. The benefits of biotech: as the world's population grows, environmental stewardship will require science to find ways to produce more food on less land.

Agriculture). Regulation. (2003): 22 March.

Phillips, G.C., M.A. O'Connell, I.M. Ray, R.G. Cantrell, and C. Sengupta-Gopalan.

The Importance of Plant Biotechnology in the Future Development of Arid
View Full Essay

Human Genome Project and Its

Words: 2561 Length: 10 Pages Document Type: Essay Paper #: 46535812

"

The ethical concerns about the ability to obtain this information revolve around the possibility of discrimination against people who have less than superior gene pools and that those people will be shunned from society, or worse yet, rounded up and locked up before they have ever done anything wrong.

In addition there is also the concern that the wealthy will be able to genetically order perfect children with the highest IQ's the healthiest DNA and the best looks, while those who are not wealthy will have children the old fashioned way and there will be an eventual class distinction between the children who have been genetically ordered and those who are a toss of the dice.

The other ethical issue involves a perceived right to privacy. The recent health care privacy act has worked to further protect a person's right to decide who has information about him and why…… [Read More]

References

Bailey, Ronald (2001) Does Genetic Engineering Endanger Human Freedom?

The American Enterprise

Brave, Ralph (2001) Governing the Genome: WHICH GENETIC MODIFICATIONS SHOULD BE ENCOURAGED AND WHICH OUTLAWED? DEEP DIVISIONS EXIST EVEN AMONG ETHICAL SCIENTISTS AND INFORMED ACTIVISTS.

The Nation
View Full Essay

Morality of Cloning in Her Book Discovering

Words: 3583 Length: 9 Pages Document Type: Essay Paper #: 99058078

Morality of Cloning

In her book "Discovering Right and Wrong," Louis Pojman consistently makes the same point throughout her chapters: beyond all the debate and lack of consensus, and beyond all the confusion of relative morality, there should exist a true objective standard which a rational being can discover. In all her writing she seems to challenge the readers to look for objective evidence of truth, a plea which often has much in common with a more conservative position on politics and morality. When it comes to the issue of cloning, however, it seems that the search for rational objective evidence is frequently put aside in favor of often illogical "gut reactions." It is high time that a truly reasonable approach to cloning was attempted. In order to best approach this from an objectivist standpoint, it seems reasonable to backtrack to one of the founding fathers of modern objectivism, Immanual…… [Read More]

Bailey, Ronald. (1998) "The Standard Objections to Cloning Won't Bear Examination." Cloning: For and Against. New York: Open Court Publishing. 129.

Christopher bard quoted in: Bailey, Ronald. (1998) "The Standard Objections to Cloning Won't Bear Examination." Cloning: For and Against. New York: Open Court Publishing. 126.

Bailey, Ronald. (1998) "The Standard Objections to Cloning Won't Bear Examination." Cloning: For and Against. New York: Open Court Publishing. 127
View Full Essay

Most Significant Advancement's

Words: 989 Length: 3 Pages Document Type: Essay Paper #: 25812474

Medical Advancements in Medicine and Health

Write a three-page paper on what you believe is the most significant medical advancement (s) in medicine and health and support your argument.

Genetic engineering is one of the most significant medical advancements of the century and will have a major impact on medicine, health, politics and church and state relationships.

Genetic engineering. A controversial issue or a blessing in disguise? The Human Genome Project (HGP), sponsored in the United tates has created the field of genomics --understanding genetic material on a large scale.

But what actually is genetic engineering? Genetic engineering in theory, allows cells to grow in a petri dish, with the end result of creating the type of genetic alteration you want. Imagine the medical ramifications of being able to genetically create the characteristics we want in a species. Think of the benefits to mankind and the enhancements that would be…… [Read More]

Sources of Information:

Publications www.ornl.gov/hgmis/publicat/genechoice/index.html" Your Genes, Your Choices --a downloadable booklet describing the Human Genome Project, the science behind it, and the ethical, legal, and social issues raised by the project

Books www.ornl.gov/hgmis/publicat/hgn/v9n1/15cshl.html" Toward the 21st Century: Incorporating Genetics into Primary Health Care

Newsletters

Human Genome News --the newsletter of the HGP sponsored by the U.S. Department of Energy Biological and Environmental Research Program
View Full Essay

Thomas Kuhn's Theory of Scientific

Words: 2630 Length: 8 Pages Document Type: Essay Paper #: 36451192

This was based on what little normative science could be carried out through crossing different animals. It was an accepted fact to many in the animal husbandry business. The first creative breakthrough occurred in 1868 when a young Swiss physician, Freiderich Meischer, isolated something that had not been seen before. This creative scientist isolated nucleic acid, a compound found in both DNA and RNA (Fredholm). This discovery sparked a quest to understand more about nucleic acid and its connection to Mendel's pea experiments just two years earlier. Mendel believed that the traits seen in peas were passed on through "packages" that contained the information (Fredholm). These packages later turned out to be DNA.

These discoveries led to the normal science processes and a quest to learn more about DNA and its connections to selective breeding. However, in mainstream practice, many had not heard of DNA yet, it had not reached…… [Read More]

Works Cited

Fredholm, L. The Discovery of the Molecular Structure of DNA - The Double Helix. 2003.

Nobelprize.org.

< http://nobelprize.org/educational_games/medicine/dna_double_helix/readmore.html

Accessed July 3, 2009.
View Full Essay

Genetic Load in Modern Humans

Words: 647 Length: 2 Pages Document Type: Essay Paper #: 84851293

By treating genetic disorders, natural selection is interrupted -- these individuals do not die as they naturally would have, and so their genetic disadvantage no longer selects against them. iT could be argued, however, that humans have stopped evolving as biological creatures anyway; technology has provided the "cure" to many issues of natural selection, both from the species end of things and from the supply side (i.e. In making more resources more available to more people). Therefore, it is not really detrimental to the species as a whole to save the individuals with lethal alleles. Since we are no longer really evolving, and the prevalence of most lethal alleles is incredibly low anyway, the species as a whole is not made less healthy by the presence of these individuals or their alleles, despite the increased chance they have at procreating.

This means that traditional medical ethics, which demand that an…… [Read More]

View Full Essay

Sister's Keeper by Jodi Picoult

Words: 2811 Length: 10 Pages Document Type: Essay Paper #: 25651277

A biopsy of the bone marrow is the only way to be sure that it is leukemia.

TEATMENT

Treatments for leukemia can vary depending on the stage, the age of the patient, the type of leukemia, and the advanced or infant stages that it is in, but most leukemia patients do go through a host of treatments that include chemotherapy.

Treatment also depends on the stage that the disease is placed in. Staging is simply a method by which the cancer is categorized for the purpose of developing a treatment plan and for research purposes with regards to cure rates and treatment successes or failures (Leukemia (http://www.emedicinehealth.com/leukemia/article_em.htm).

In most cases of the disease, including Kate's case the treatment of choice is chemotherapy. There is a scene in the novel in which Anna, Kate and their mother are dancing around the kitchen together after shaving their heads so Kate would not…… [Read More]

References

Leukemia (Accessed 11-11-06)

http://www.emedicinehealth.com/leukemia/article_em.htm

Signs and Symptoms (accessed 11-12-06)

http://www.oncologychannel.com/leukemias/symptoms.shtml
View Full Essay

Hemophilia the Most Common Genetic

Words: 3476 Length: 11 Pages Document Type: Essay Paper #: 95055081

The viruses that cause AIDS (HIV) and hepatitis can be carried in clotting factors however there have been no documented cases of such transmission in about ten years. Prevention of viruses can be prevented by: careful screening of donors; testing of donated blood products; treating donated blood products with a detergent and heat to destroy viruses (Hemophilia 2006). Both preventive and as-needed therapy can be administered at home, thus resulting in quicker treatment, fewer doctor or emergency room visits, and less costs. Vein access devices can be surgically implanted to allow easier access to a vein however infections can result from such devices (Hemophilia 2006).

All patients with bleeding disorders may benefit at times from using aminocaproic acid, an oral antifibrinolytic medication that helps stabilize clots (Curry 2004). Aminocaproic acid is the only product available in the United States in oral form, however it is not user-friendly, with dosing every…… [Read More]

Works Cited

Anderson, Gaylene. (2006 October 06). Promising Non-Viral Alternative for Gene Therapy

Involves 'Jumping Gene' From a Moth. Ascribe Higher Education News Service. Retrieved December 20, 2006 from HighBeam Research Library.

Bayer Grant Promotes Groundbreaking Hemophilia Research and Education; Bayer Hemophilia

Awards Program Continues to Be a Critical Source of Funding for Hemophilia Research and Education. (2006 May 23). Business Wire. Retrieved December 20, 2006 from HighBeam Research Library.
View Full Essay

Ground Breaking and Innovative Instances

Words: 2229 Length: 6 Pages Document Type: Essay Paper #: 71397766

The exchange of the defective gene could be brought about by a process called homologous recombination. One of the first gene therapy experiments, though well intentioned, caused the death of the patient. esearchers at the University of Pennsylvania introduced a normal gene into a boy's body by using the rhino virus as a carrier. The body's immune system attacked this as a pathogen. This led to eventual organ failure and death. Gene therapy projects all over the world were largely abandoned. But more recently, gene therapy is beginning to make a comeback. (ONL, 2009)

Gene therapy has been tested in the treatment of Alzheimer's disease. This is not a treatment that targets amyloid beta proteins or the tangles, but protects the brain cells from destruction. The regenerative properties of skin cells (stem cells) have been used to prevent the brain cells from "withering" away. Positron Emission Tomography (PET) scans reveal…… [Read More]

References

http://www.alzforum.org/drg/drc/detail.asp?id=84Alzforum. (2009). Retrieved April 18, 2009, from BBC. (2003). Alzheimer's vaccine 'promising'. Retrieved April 18, 2009, from Alzheimer's vaccine 'promising'

ChemoCare. (2005). Taxol. Retrieved April 18, 2009, from http://www.chemocare.com/bio/taxol.asp

Elements4health. (2009). PET Scans Reveal Plaques and Tangles In Alzheimer's Retrieved April 18, 2009, from http://www.elements4health.com/pet-scans-reveal-plaques-and-tangles-in-alzheimers.html

Feng, J.A., Crasto, C.J., & Matsumoto, Y. (1998). Deoxyribose phosphate excision by the N-terminal domain of the polymerase beta: the mechanism revisited. Biochemistry, 37(27), 9605-9611.
View Full Essay

Detection and Intervention in Childhood Mental Health

Words: 10566 Length: 30 Pages Document Type: Essay Paper #: 97642961

detection and intervention in childhood mental health help prevent mental health problems in adult life?

Disregarding the mental well-being requirements of children is an intolerable violation of our basic undertaking to protect their well-being. Unfavorable mental disposition amidst our children is a less acknowledged difficulty that influences their literary, societal, and emotional enhancement. Mental well-being is a wide attribute to be analyzed. The mental well-being requirements of children and youth demand introspection. There is prevalent refuting that mental well-being is comprehensive of the influence on the children -- amidst all age distinct ions, variety of cultural sections, and all income sections. Such miscomprehensions are recurring, and involvement and care are unlikely to be found. Many people have the belief that children having mental well-being difficulties are just under the impact of a particular passing cloud. (Promoting Access for Children to Mental Health Screens and Assessments in Medicaid and the Children's…… [Read More]

References

AAMR. "Mental retardation: Definition, classification, and systems of supports," 9th edition (1992).

Caplan G. "Principles of Preventive Psychiatry," Basic Books, New York, 1964

Children's Mental Health: Current Challenges and a Future Direction Traditional Mental Health Services for Children: Current Arrangements and Challenges." Retrieved at http://www.healthinschools.org/mhs3.asp. Accessed on 12/08/2003

Children, Youth and Mental Disorders." The Primer May, 2003
View Full Essay

Use of Stem Cells in Parkinson's Patients

Words: 2013 Length: 6 Pages Document Type: Essay Paper #: 79904362

Stem Cell Research / Parkinson's

Since Barack Obama has become president, the field of stem cell research has been given new life. One of Obama's campaign pledges

was to allow deeper research -- including the use of federal research funds -- into the use of pluripotent stem cells in order to find solutions for some of the terrible diseases Americans suffer from. Among those medical problems is Parkinson Disease (PD). This paper reviews and delves into the literature in terms of the potential of stem cell interventions into Parkinson Disease (also called "Parkinson's Disease").

ho is the leading authority on stem cell research?

There is no one "leading authority" reflected in the literature; however there are renowned scientists that are considered pathfinders in this field. Dr. Diane S. Krause, Associate Professor of Laboratory Medicine and Associate Director of Stem Processing at Yale University is "…one of the discoverers of previously…… [Read More]

Works Cited

Gallup Poll. (2011). Stem Cell Research. Retrieved March 7, 2012, from  http://www.gallup.com/poll/21676/stem-cell-research.aspx .

Gogel, S. Gubernator, M., and Minger, SL. (2011). Progress and prospects: stem cells and Neurological diseases. Gene Therapy, 18(1), 1-6.

Krause, D.S. (2002). Plasticity of marrow-driven stem cells. Gene Therapy, 9(11), 754-8.

Lo, Bernard, and Parham, Lindsay. (2010). Resolving Ethical Issues in Stem Cell Clinical
View Full Essay

Treatment History of Cystic Fibrosis

Words: 1699 Length: 5 Pages Document Type: Essay Paper #: 91316181

Treatment History Of Cystic Fibrosis

The field of pediatric nursing is a particularly large one in which its members may find themselves having to counsel both young patients and their families suffering from a myriad of diseases. Cystic fibrosis (CF), in particular, is a debilitating disease that strikes many young people. In the first years following its discovery, many children could not expect to make it to their teen years. Today, with advances in the management and care of this disease, patients are living into their 40s. It is even possible that there will one day be a cure.

This paper will look at CF from a historical perspective. The timeline of its discovery and research will be briefly presented, as will a few of the significant "milestones" in the history of the treatment of CF and what these mean for people battling this disease.

References to cystic fibrosis were…… [Read More]

Bibliography

Author not available. (1994). Genetic Therapy Possible Cure for Several Diseases. Morning Edition (NPR).

Baroni, M.A., Anderson, Y.E., and Mischler, E. (1997). Cystic fibrosis newborn screening: Impact of early screening results on parenting stress. Pediatric Nursing. 23, 143(9).

Hopkin, Karen. (1998). Understanding Cystic Fibrosis. Jackson, MS: University Press of Mississippi.

Orenstein, David M. (1997). Cystic Fibrosis: A Guide for Patient and Family. 2nd ed., Philadelphia, PA: Lippincott-Raven.
View Full Essay

History and Industry Trends

Words: 922 Length: 3 Pages Document Type: Essay Paper #: 10587961

Information Technology

1985 "Hacking," or entering / gaining unauthorized access to a computer system, has been committed by a group of young computer programmers. The victims of this new incidence of hacking were the Pentagon and the telecommunications company, AT&T.

Nuclear energy became the primary source of energy used in weapons making, characterized to be more efficient and powerful compared to its predecessor, the atomic bomb (energy).

1986 The first operation was conducted which granted a patient an artificial heart, lengthening the life survival of patients who have poor heart conditions.

1988 Stealth bomber aircrafts were manufactured and introduced by the United States. These new aircrafts provide ease and increasingly rapid speed of flight without being detected by enemy radar (especially during war time).

1990 Switzerland had produced the first solar-powered vehicle, which runs on solar power alone, without the use of excessive fuel energy. This project aims to provide…… [Read More]

Bibliography

Daniel, C. (Ed.). (1993). Chronicle of the 20th Century. NY: JL International Publishing.

McNeil, I. (2002). An Encyclopedia of the History of Technology. NY: Routledge.

Microsoft Encarta Reference Library 2002. Microsoft Corporation 1983-2001.
View Full Essay

Baldness and Thinning Hair Are Common and

Words: 1673 Length: 6 Pages Document Type: Essay Paper #: 66118409

aldness and thinning hair are common and the ultimate fate of almost all men and women as they age. In fact, hair loss is genetic in origin, and as we come to a greater understanding of the biology and genetics of hair loss, we are beginning to find novel solutions to this age-old "problem" of the human condition. We have come a long way from the treatments for hair loss in ancient Egypt, which used a mixture of crocodile fat and hippopotamus dung to combat baldness. Another ancient cure for baldness included eating fried leeches. Men have been attempting to treat their hair loss for over 5000 years, beginning in approximately 3500 C, when a list of treatments was passed on from generation to generation and incorporated into the medical libraries of Egyptian healers. In 1553 C, the Ebers Papyrus, discovered in Luxor, Egypt, suggested a baldness prescription of iron,…… [Read More]

Bibliography

Bruning, Nancy Paul. What You Can Do About Chronic Hair Loss (The Dell Medical Library) Dell, 1993.

Jacobs, Sheila. The Big Fall: Living With Hair Loss Next Century Books, 1992

Kobren, Spencer David; Eisman, Diane B; Eisman, Eugene H. The Bald Truth: The First Complete Guide to Preventing and Treating Hair Loss, Pocket Books. 2000

Kobren, Spencer David; Christiano, Angela. The Truth About Women's Hair Loss: What Really Works for Treating and Preventing Thinning Hair. Mcgraw Hill, 2000.
View Full Essay

Tourette's in Children

Words: 1840 Length: 5 Pages Document Type: Essay Paper #: 86979836

Tourette Syndrome in Children

hat is Tourette Syndrome?

Tourette Syndrome (TS) is an inherited neurological disorder generally associated with tics. Tics are defined as either involuntary body movements, or involuntary vocal sounds that are usually repetitive. The occurrence of TS in children is about 1 of every 2000 children, with an increased occurrence in boys as opposed to girls. The syndrome itself is named for the French neurologist Dr. George Gilles de la Tourette, who diagnosed the first patient with the illness in 1885.

How do you know if you have it? (Symptoms and Diagnosis)

Diagnosis specifics vary from one source of information to the next. Some publications, such as the website for the Jim Eisenreich Foundation for Children, suggest waiting until the tics are present for at least one year, and that multiple tics must be shown - vocal and physical (though not at the same time). Other sites…… [Read More]

Works Cited

Tourette-Syndrome Online. Craig Whitley, Ed. "Facts About Tourette Syndrome http://www.tourette-syndrome.com/tourette-syndrome-facts.htm3Apr 2002

Tourette-Syndrome Online. Craig Whitley, Ed. "Facts About Tourette Syndrome" 3 Apr 2002. http://www.tourette-syndrome.com/tourette-syndrome-facts.htm3Apr 2002

Tourette Syndrome Association, Inc. "Tourette Syndrome's Frequently Asked Questions" 3 Apr 2002. http://www.tsa-usa.org/wrapper.php.3/00/Faqs.html

Tourette-Syndrome Online. Craig Whitley, Ed. "Facts About Tourette Syndrome" 3 Apr 2002. http://www.tourette-syndrome.com/tourette-syndrome-facts.htm
View Full Essay

Hemophilia Is Not One but

Words: 1361 Length: 5 Pages Document Type: Essay Paper #: 69626859

Occurrence of inherited hemophilia is slightly more likely in Caucasians (1.3%) as opposed to African-Americans (1.1%) and Hispanic (1.2%). Asian populations appear to inherit the gene far less likely, about 1/4 of that of Caucasians. However, modern demographics result in marriage between ethnic types far greater than previous, and statistics show a blending to about 1% of most populations (Soucie, et.al., 1998.)

Abnormality -- as a genetic occurrence, hemophilia infects about 1 in 5,000 male births, but carried in another 5,000 female births. The disease is recessive in females (carried on X-chromosome). Thus, a carrier female has a 50% chance of passing on the defective X chromosome to her daughter, while a male who is affected will always pass on that defect to progeny.

Screening/Testing -- Genetic testing based on family history is the primary mechanism for discovering hemophilia, but certain other tests help quantify the assurance:

Pronounced bleeding at…… [Read More]

REFERENCES

Agaliotis, D., et.al. (2009). "Hemophilia -- Overview." EMedicine. Cited in:

http://emedicine.medscape.com/article/210104-overview

Handin, R., et.al., eds. (2003). Blood Principles and Practice of Hemotology."

Thomas Stossel.
View Full Essay

Beta Thalassemia

Words: 1013 Length: 3 Pages Document Type: Essay Paper #: 45245449

Beta Thallasemia

Beta Thalassemia

Beta thalassemia is the severer of the two main types of thalassemia -- an inherited blood disease resulting from defective production of hemoglobin. About 100,000 people are born worldwide every year with beta thalassemia which occurs most frequently in people of Italian, Greek, Middle Eastern, Southern Asian and African Ancestry. (Learning about...," 2004) People with beta thalassemia usually develop anemia, resulting in inadequate delivery of oxygen to the body's tissues and it proves fatal in most cases, if left untreated. In this paper we shall discuss the disease develops; the types of beta thalassemia, how it is inherited, its symptoms, diagnosis and treatment.

How Beta Thalassemia develops?

Hemoglobin, the protein that transports oxygen in the blood, is made up of four chains of amino acids: two identical alpha chains and two identical beta chains. Thalassemia is the result of an imbalance in the production of beta…… [Read More]

References

Beta Thellasemia." (2001) Child Health A-Z. Website of Children's Hospital, Boston Updated on 04/03/2004. Retrieved on April 4, 2003 at http://web1.tch.harvard.edu/cfapps/A2ZtopicDisplay.cfm?Topic=Beta%20Thalassemia

Beta Thellasemia." (2004) Medicinenet.com. Retrieved on April 4, 2003 at http://www.medicinenet.com/Beta_Thalassemia/article.htm

Learning About Thalassemia." (2004) National human Genome research institute. Genome.gov. Retrieved on April 4, 2003 at http://www.genome.gov/page.cfm?pageID=10001221

Nathan, David G. And Nisbet-Brown, Eric. (2003). "Thalassemia." Article in Encyclopedia Encarta, 2003
View Full Essay

Engineered Crops the Rapid Advancements

Words: 1088 Length: 4 Pages Document Type: Essay Paper #: 80687274

Glyphosate tolerant weeds started to grow uncontrollably requiring the use of greater quantities of pesticides than was necessary conventionally. [ranford, Sue]

Gene Contamination

Another problem is the increasing possibility of gene pollution on traditional crops by GM crops. In a brief article, which discusses the health dangers of genetically modified foods, the author cites a recent study by the UCS (Union of Concerned Scientists). In the study, which analyzed samples of conventionally grown crops such as maize, soybeans and canola, it was found that more than half of the seeds were contaminated to some level. As the report indicated the samples under study were, "pervasively contaminated with low levels of DNA sequences from GM varieties." [: Pearce, Fred] a clear example of this type of contamination is the shocking finding that traditional Mexican maize had genetically engineered genes. This problem will be more dangerous if pharming crops contaminate conventional crops.…… [Read More]

Bibliography

1) John Pickrell, "GM Organisms," New Scientist, Special Report, 13/12/2004

2) Branford, Sue, "Argentina's Bitter Harvest," New Scientist, 4/17/2004,

Vol 182 Issue

3) Pierce, Fred, "Gene Pollution is Pervasive," New Scientist, 2/28/2004,
View Full Essay

Alopecia Areata Is a Systemic Hair Loss

Words: 2403 Length: 9 Pages Document Type: Essay Paper #: 97622246

Alopecia areata is a systemic hair loss disorder, which affects roughly around 4.7 million people in the United States alone. [NAAF]. It is characterized as an autoimmune disease that leads to either localized or complete hair loss. The disease is independent of race, gender or age specifications, and hence affected people represent a diverse group. The effects of the disease may either be permanent or reversible depending on the nature and extent of damage to the hair follicles. It is believed that both genetic as well as environmental factors have an influence in the onset of the condition. However, the pathology of the disease is yet to be ascertained concretely. Though there is no physical distress accompanying the disease the psychological devastation suffered by the affected person is debilitating. Let us have a brief overview of the different types of alopecia before we discuss in detail the possible pathophysiology and…… [Read More]

Bibliography

1) NAAF, "What is Alopecia Areata," Accessed on March 8th 2005,

http://www.naaf.org/default2.asp

2) Ralph Paus, M.D and George Cotsarelis, M.D, "The Biology of Hair Follicles," NEJM, Vol 341, No 7, Pg 491.

3) Kyle Kennedy, M.D, "Management of Alopecia," Accesses on March 9th 2005,
View Full Essay

Trends in the Provision of Health Sciences Information Resources

Words: 1450 Length: 5 Pages Document Type: Essay Paper #: 52990908

Health Sciences Information esources

Ernst & Young (2001) describe the global health sciences marketplace as "a web created by pharmaceutical companies, biotech firms, eHealth companies, hospitals, physicians and other practitioners and medical device manufacturers" to name a few (p.1). This web or library of information is the wave of the future. Health sciences information libraries of the future will not just serve as global resources of health care information, but will rather serve as collaborative and interactive repositories where patients will be able to discover individualized treatment options and health care providers can collaborate on new biotechnological advances and discoveries.

The global health sciences marketplace and libraries are inexorably changing as technology is better enabling corporations, individuals and providers to provide services in new and faster ways. Trends developing within the industry that will affect health sciences libraries include providing health products and services that are delivered "Through integrated alliances"…… [Read More]

References:

Aday, L.A., Begley, C.E., Lairson, D.R. & Slater, C.H. (1993). Evaluating the medical care system: Effectiveness, efficiency, and equity. Ann Arbor: Health Administration Press.

Anton, P.S., Schneider, J. & Silberglitt, R. (2001). The global technology revolution:

Bio/Nano/Materials trends and their synergies with information technology. Santa Monica: Rand.

Brook, R.H., Damber, C. & Ker, E.A. (1998). Health information systems: Design issues and analytic applications. Santa Monica: Rand.
View Full Essay

Hemophilia Is an Inherited Disorder

Words: 729 Length: 3 Pages Document Type: Essay Paper #: 54516905

Gene therapy is another method that can help replace defective genes in carriers to protect future generations but this is a highly expensive procedure that not everyone can afford. Hemophilia has a long history and it has been found in members of the royal family of England.

There are some important facts that we should know about hemophilia since they help in dispelling popular myths. Not all forms of hemophilia are caused by deficiency in Factor VIII. While 80% of hemophilic cases are like that, the rest are affected by hemophilia B. that is actually a deficiency in Factor IX.

It is also believed that patients with hemophilia have medical family history of the disease. But that is not entirely true. In almost 1/3 cases of hemophilia, there was no family history found. It is claimed that in these patients, the onset of disease is spontaneous. Some abrupt gene mutation…… [Read More]

REFERENCE

Hemophilia" the Columbia Encyclopedia, Sixth Edition; 4/22/2004

New treatment for hemophilia. (Updates) FDA Consumer; 11/1/2003
View Full Essay

A Nurse Themed Reflection

Words: 963 Length: 3 Pages Document Type: Essay Paper #: 25680657

difficult because I was being introduced to everything. I had no idea that being a nurse meant integrating information for so many diverse fields. When I finished the week I had learned and grown so much as an individual and as a nursing student. I learned that I needed to be acquainted with various subjects in order to pull information and reference things that could help me perform my duties as a nurse. I also learned of the many new topics of interest in current healthcare and how a field like genetics could play a role in medicine and treatments. The focus of nursing is quality improvement and the first week helped me understand how to pursue quality care.

The second course week I learned how to build processes that promote quality improvement as well as safety in healthcare delivery. I had to learn how to be a leader and…… [Read More]

References

Gibbon, S., Joseph, G., Mozersky, J., Zur Nieden, A., & Palfner, S. (2014). Breast Cancer Gene Research and Medical Practices. Routledge.

Glazer, G., & Fitzpatrick, J. (2013). Nursing leadership from the outside in. New York: Springer Pub. Co.

Lilley, L., Collins, S., & Snyder, J. (2015). Pharmacology and the nursing process (p. 98). Elsevier Health Sciences.
View Full Essay

Physiological Effects of Hodgkin's Disease in This

Words: 1599 Length: 4 Pages Document Type: Essay Paper #: 71218996

Physiological Effects of Hodgkin's Disease

In this paper I shall give an overview of Hodgkin's disease while focusing on its physiological effects. Specifically, the paper consists of an overview of the disease, describes how the disease affects the body cells and tissues, and how the treatment attacks the disease and affects the body, besides reviewing the treatments available.

Hodgkin's disease is one of the two (and less severe) types of cancer of the lymphatic system; the other type being non-Hodgkin's lymphoma. The disease is named after the British physician, Thomas Hodgkin, who first discovered the condition in 1832. Hodgkin's disease commonly occurs in young adults (between the ages of 15 to 35) and in older people (over 50-year-olds. However, about 10%-15% of cases have been diagnosed in children below 16 years of age. Statistics also show that more men than women are afflicted by it. ("What are the Key Statistics…… [Read More]

References

'Autologous Bone Marrow Stem Cell Transplantation" (2004). American Cancer Society. Retrieved on September 28, 2004 from http://www.cancer.org/docroot/CRI/content/CRI_2_4_4X_Autologous_Bone_Marrow_Stem_Cell_Transplantation_and_Peripheral_Blood_Stem_Cell_Transplantation_20.asp?rnav=cri 'Chemotherapy." (2004). American Cancer Society. Retrieved on September 28, 2004 from http://www.cancer.org/docroot/CRI/content/CRI_2_4_4X_Chemotherapy_20.asp?rnav=cri 'Do We Know What Causes Hodgkin's Disease?" (2004). American Cancer Society. Retrieved on September 28, 2004 from http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_Do_we_know_what_causes_Hodgkins_disease_20.asp?rnav=cri

"Hodgkin's Disease." (2000) The Columbia Encyclopedia, Sixth Edition. Columbia University Press: New York.

'Hodgkin's disease: Overview" (2004) Oncology Channel Retrieved on September 28, 2004 from http://www.oncologychannel.com/hodgkins / 'How is Hodgkin's Lymphoma and the Non-Hodgkin's Lymphomas Different?" (2004) Lymphoma Information Network. Retrieved on September 28, 2004 from  http://www.lymphomainfo.net/lymphoma/comparison.html 

'How Is Hodgkin's Disease Treated?" (2004). American Cancer Society. Retrieved on September 28, 2004 from http://www.cancer.org/docroot/CRI/content/CRI_2_4_4X_How_Is_Hodgkins_Disease_Treated_20.asp?rnav=cri 'The Lymphatic System." (2004) CancerBACUP. Retrieved on September 28, 2004 from http://www.cancerbacup.org.uk/Cancertype/LymphomaHodgkins/General/Thelymphaticsystem
View Full Essay

Stem Cells and Umbilical Cords

Words: 4604 Length: 17 Pages Document Type: Essay Paper #: 68647678

Scientists have been aware of the existence of these stem cells for many years but have only recently realized the potential medical applications of the cells. More than a decade ago, scientists discovered that if the normal connections between the early cellular progeny of the fertilized egg were disrupted, the cells would fall apart into a single cell progeny that could be maintained in a culture. These dissociated cells, otherwise known as embryonic stem cell lines, continue to divide in culture, producing large numbers of cells at a fast pace. However, these early embryonic cells would lose the coordinated activity.

Scientists quickly discovered that these cells retain the ability to generate a great number of mature cell types in culture if they are provided with appropriate molecular signals (Reaves, 2001). Scientists have made significant progress in discovering these signals and are still working on it. hile it is a difficult…… [Read More]

Works Cited

Colino, Stacey. (2001). Making Sense of Stem Cells. Lifetime.

Prescott, Bonnie. (2001). Animal Study Find Embryonic Stem Cells Can Repair Heart Muscle. Beth Israel Deaconess Medical Center.

Reaves, Jessica. (2002). The Great Debate Over Stem Cell Research. Time Magazine.

Recer, Paul. (2002). Study says stem cells have fewer mutations than previously thought. AP Online.
View Full Essay

CONNEXIN43 Expression Following Retinal Ischemia

Words: 4785 Length: 19 Pages Document Type: Essay Paper #: 33589871

" (Volpicelli-Daley and Levey, 2003)

Prior to visualization of the molecule of interest it is necessary to "fix and section the brain tissue. Double-labeling immunofluorescence is stated to detect "localization of a protein of interest as well as the distribution of the protein relative to another marker such as a neurochemical or organelle marker." (Volpicelli-Daley and Levey, 2003 Fluorescence imaging labeled tissue through use of confocal makes provision of "high-resolution analysis of the extent of colocalization, with a theoretical limit of resolution of 0.1 to 0.2 um." (Volpicelli-Daley and Levey, 2003) Immunofluorescence techniques are stated to "in general...utilize secondary antibodies conjugated to a flurosphore." (Volpicelli-Daley and Levey, 2003) It is important according to Volpicelli-Daley and Levey to choose flurosphores with "minimal background staining and a minimum overlap of excitation/emission spectra...when performing double labeling experiments." (2003)

IV. FLUORESCENCE MICROSCOPY

The work of Coling and Kachar (1997) entitled: "Theory and Application of…… [Read More]

Bibliography

Apoptosis (2009) Protocol Online. Available at:  http://www.protocol-online.org/prot/Cell_Biology/Apoptosis/index.html 

Coling, Donald and Kachar, Bechara (1997) Theory and Application of Fluorescence Microscopy. Current Protocols in Neuroscience. John Wiley & Sons.

Gallagher, S., Winston, S.E, Fuller, S.A. And Hurrell, J.G.R. (2004) Immunoblotting and Immunodetection. Current Protocols in Neuroscience 2004. John Wiley & Sons.

Introduction to Immunohistochemistry (2009) IHC World Life Science Information Network. Online available at:  http://www.ihcworld.com/_intro/intro.htm
View Full Essay

Controversial Bioethical Issues of the

Words: 1788 Length: 5 Pages Document Type: Essay Paper #: 3993568

Chimpanzees and gorillas can be taught human sign language, and sign with one another even without humans present. (MMMC, 2002) They argue that to use intelligence and compassion as a sliding scale of the right to life would cause many humans to be justified out of existence.

However, even if one accepts that too many animals are experimented upon, and researchers should use other means, it is similarly hard to justify the elimination of all animal experimentation, altogether, as this would have meant the end of such recent drug developments in AIDS research, as well as more questionable animal tests, as for instance, the use of rabbits in cosmetic testing, for which there are acceptable substitutes that do not require animals.

orks Cited

Bayliss, Francoise. (2004) "Our Cells/Ourselves: The Ethics of Embryonic Stem Cell Research." Stem Cell Network. Retrieved 12 Jan 2004 at http://www.stemcellnetwork.ca/research/projects/project04.php

BBC News. (Feb 12, 2004)"Q &…… [Read More]

Works Cited

Bayliss, Francoise. (2004) "Our Cells/Ourselves: The Ethics of Embryonic Stem Cell Research." Stem Cell Network. Retrieved 12 Jan 2004 at http://www.stemcellnetwork.ca/research/projects/project04.php

BBC News. (Feb 12, 2004)"Q & A: Cloned Embryos." BBC Official Website. Retrieved 12 Jan 2004 at http://news.bbc.co.uk/1/hi/sci/tech/3481159.stm

Bird, Gloria W. And Sporkowuski, Michael J. (1992) Taking Sides. The Dushkin Publishing Group, Inc. Guilford, CT.

CNN.com. (Feb 12, 2004)" Scientists 'cloned human embryos' CNN News Website. Retrieved 12 Jan 2004 at http://www.cnn.com/2004/HEALTH/02/12/science.clone/
View Full Essay

Moral Analysis the Food and

Words: 2417 Length: 8 Pages Document Type: Essay Paper #: 73000088

I have a clear written mandate that guides this decision. The other alternatives do not have the same clear, written mandate as the one that I made. hile a utilitarian approach may have yielded a different decision, in my position as a safeguard of public safety I am not obligated to undertake a utilitarian position unless I can do so without compromising my primary mandate. This is something I was able to do with generic drugs that I cannot do with biosimilars, even though it would be expedient for me to ignore the differences between the two products.

There are certainly those who would object with this decision. A utilitarian in particular would have a strong argument that total health outcomes depend not only on drug safety but on availability as well. I would argue, however, that this objection is invalid for a couple of reasons. The most important of…… [Read More]

Works Cited:

Van Arnum, P. (2010). Healthcare reform draws mixed reviews from pharmaceutical and biotechnology industries. PharmTech.com. Retrieved December 8, 2010 from http://pharmtech.findpharma.com/pharmtech/Regulation/Healthcare-Reform-Draws-Mixed-Reviews-from-Pharmac/ArticleStandard/Article/detail/662434?contextCategoryId=48563
View Full Essay

Skills Regarding Nursing Care Nursing

Words: 887 Length: 3 Pages Document Type: Essay Paper #: 1093923



Informed Decision Making (Nursing Role)

The nurse has the utmost responsibility in educating the patient and his/her family about the proposed treatment plan, the availability of alternative interventions, and in general plays a vital role in promoting informed decision making. [ANMC], (2005)] The nurse being more familiar with the patient has a better understanding of the patient's understanding capabilities and can therefore decide as to what type of teaching method a patient is best suited for. While for some patients a simple printed information leaflet is suffice for others a more detailed presentation involving a video maybe necessary. This again helps the patient better understand the procedures and helps them in their decision making process. [Mark H. eers, (2006)] In the case of new treatment modalities that are available with recent medical advancements, the nurse can greatly assist the patient in making well-informed decisions about the available treatment choices. Gene…… [Read More]

Bibliography

1) ANMC, (2005), ' Code of Ethics of Nurses in Australia', retrieved 5th Sep 2010, from,  http://www.nrgpn.org.au/index.php?element=ANMC+Code+of+Ethics 

2) Jeanette Ives Erickson, RN, (2005), 'Caring for Patients while Respecting their Privacy: Renewing our Commitment ', retrieved 5th Sep 2010, from, http://www.medscape.com/viewarticle/506840

3) ISONG, (2005), 'Informed Decision Making and Consent: The Role of Nursing', retrieved Sep 5th 2010, from, http://www.isong.org/ISONG_PS_informed_consent.php

4) Mark H. Beers, MD & Thomas V Jones MD et.al, (June 2006) 'The Merck Manual of Geriatrics: Chapter 8: Nursing', Pub by Merck Sharp & Dohme Corp.
View Full Essay

Healthcare World Industries the Healthcare

Words: 836 Length: 2 Pages Document Type: Essay Paper #: 95538372

Human Resources planning and strategy will be 'key' in enabling the organization to deal with pandemic situations. This leads to another primary challenge that the health care industry faces which is the shortage of nursing staff in today's health care organizations and institutions. Nursing staff in the healthcare industry re under great stresses on staffing due to an inadequate supply of individuals pursuing their nursing degree with an."..unprecedented demand for nursing services" however, colleges and universities as well as health care institutions have failed to develop effective workforce supply. The work of leich and Hewlett (2004) entitled: "Dissipating the Perfect Storm - Responses from Nursing and the Health Care Industry to Protect the Public's Health" published by the Journal of Issues in Nursing states: "In spite of the progress in nurse recruitment, the prognosis for balancing supply with demand is still precarious, at best. Sadly, AACN (2003a) reports that more…… [Read More]

Bibliography

Bleich, Michael R. And Hewlett, Peggy O. (2004) Dissipating the Perfect Storm - Reponses to Nursing and the Health Care Industry to Protect the Public's Health. Online Journal of Issues in Nursing. Vol. 9 No.2, May 2004. Online available at  http://www.nursingworld.org/MainMenuCategories/ANAMarketplace/ANAPeriodicals/OJIN/TableofContents/Volume92004/No2May04/DissipatingthePerfectStorm.aspx 

Bureau of Labor Statistics, U.S. Department of Labor, Career Guide to Industries, 2008-09 Edition, Health Care, on the Internet at http://www.bls.gov/oco/cg/cgs035.htm (visited March 11, 2008).

Business Continuity Planning for the Global Healthcare Industry (2007) International Federal of Pharmaceutical Manufacturers and Associations. Jan 2007 IFPMA.

Memorandum
View Full Essay

Sensory Loss in the Aged

Words: 2128 Length: 6 Pages Document Type: Essay Paper #: 41165511

If an underlying condition is the cause of the loss, then the logical procedure would be to treat the underlying cause. In some cases the sense of smell may return and for others the loss will be permanent.

Research supports the existence of changes in smell due to age. The causes of this loss are varied. There has not been considerable research into searching for a treatment as with other sensory declines. Loss of out sense of smell is not considered to be of greater consequence in our society. ith the rare exception of those whose careers depend on it, there is little societal impact caused by a loss of sense of smell. For the person, they may not enjoy all of the things that they used to, but it does not carry any significant impairment with it.

There has been no formal effort dedicated towards research to restore the…… [Read More]

Works Cited

Arabi, A. (2004) Cochlear Implants: My Perspective. Term Paper. NBB421 - Effects of Aging on Sensory and Perceptual Systems. Professor Halpern. Friday, December 3, 2004. Cornell University, Ithaca, NY.

Bauman, N. (2004) Hair Cell Regeneration -- Overcoming the Challenges. Center For Hearing Loss Help. November 2004. http://www.hearinglosshelp.com/articles/haircellchallenge.htm. Accessed December 15, 2006.

Cain, W., Stevens, J. (1989) Uniformity of olfactory loss in aging. Ann. N.Y. Acad. Sci. 561, 29-38.

Cochlear Implants. The Virginia Merrill Bloedel Hearing Research Center at the Cochlear.org (2006a) Total Costs for the Procedure. http://www.cochlear.org/sys-tmpl/cochlearimplantcosts/. Accessed December 15, 2006.
View Full Essay

Unethical Experimentation Issues and Concerns

Words: 4124 Length: 15 Pages Document Type: Essay Paper #: 77212600

(Freyhofer 104)

Globalizing clinical research has reportedly proven to be one solution for America's pharmaceutical paradox. Doctors prescribe more than 10 prescriptions for the average American each year. Only one person in 350, however, will submit themselves to be a participant in experimental drug testing. On the other side of the globe, however a profusion of under-treated, poor, physician-trusting patients who live in Latin America, Eastern Europe, and Southeast Asia provide the rapid, positive results needed for new drugs to receive quick approval. One review noted that 99% of controlled trials published in China netted positive results upon the drug/treatment being investigated. (Shah 23) In Nigeria during 2002, thirty Nigerian families filed a class-action suit against Pfizer, who allegedly violated the Nuremberg Code in 1996 as they presided over an experiment on Nigerian children suffering with meningitis. esearchers reportedly forced a risky, unapproved, experiment on unsuspecting subjects who, as a…… [Read More]

References www.questia.com/PM.qst?a=o&d=5002068015

Bagley, Margo A. "Patent First, Ask Questions Later: Morality and Biotechnology in Patent Law." William and Mary Law Review 45.2 (2003): 469+.

Chapter 14: The Federal Policy for Human Subject Protections (The Common Rule)." Retrieved 28 November 2006 at http://www. the.doe.gov/ohre/roadmap/achre/chap14_2.html.

Embryonic stem cell research fails in many ways to reader," The Times Leader, October 27, 2006.

Fence Post." Daily Herald (Arlington Heights, IL) 27 Aug. 2005: 16.
View Full Essay

Information Technology IT Is a Broad-Based Term

Words: 1674 Length: 4 Pages Document Type: Essay Paper #: 29344536

Information Technology (IT) is a broad-based term that includes a combination of the acquisition, processing, storage and dissemination of information in a computing or telecommunications platform. In terms of a scientific discipline, it is relatively new, appearing in a 1958 article in the Harvard Business Review in which the authors said, "this new technology does not yet have a single established name. e shall call it information technology (IT)" (Dunn, 2011). The field has been part of the tremendous growth in computing and telecommunications, and remains vital -- it is behind the recent emergence of next generation web technology, bioinformation, cloud computing, global information systems, and large scale databases.

The IT area manages technology in a wide variety of fields that include software, hardware, information systems, and programming languages. IT professionals perform a wide variety of functions from installation of applications and hardware to designing and maintaining complex networks and…… [Read More]

Works Cited

Benefits of Technology use. (2003, January). Retrieved from U.S. Department of Education: http://www2.ed.gov/about/offices/list/os/technology/plan/national/benefits.html

Pros and Cons of Modern Technologies. (2008, September 17). Retrieved from Tech Aid:  http://www.techacid.com/2008/09/17/pros-and-cons-of-modern-technologies/ 

Technology Transfer in the Food Industry. (2-11, October 14). Retrieved from CSIRO: http://150.229.98.44/en/Outcomes/Food-and-Agriculture/Food-industry-technology-transfer.aspx

Dunn, J. (2011, November 11). The Fascinating History of Information Technology. Retrieved from Edudemic.com: http://edudemic.com/2011/11/history-of-it/
View Full Essay

GlaxoSmithKline and AIDS Drugs in South Africa

Words: 870 Length: 3 Pages Document Type: Essay Paper #: 32122473

eGlaxoSmithKline

As per our previous discussion, there is little doubt anymore but that our HIV / AIDS drugs are well positioned to go to the next level of modern emergent medicine. Whatever treatment modalities that will arise in the future will be ICT-based (Information Communication Technology) and will be executed in practice utilizing mHealth (mobile) practices that are part of a network of eCare (electronic), eServices, eSurvellience and eLearning structures (Sorenson et al., 2008). The past prediction appears accurate that by this year (2012), half of all people in remote but developing areas of the world will have access to mobile technology (Singh, nd). It is therefore incumbent upon GlaxoSmithKline (GSK) to establish itself as a leader in facilitating how these efforts can complement our pharmaceuticals interventions, particularly since it is now well accepted that antiretroviral interventions are the only known approach for slowing the disease progression in infected individuals.…… [Read More]

E1: The first step in this process will revolve around doing further preparation on what constitutes an effective organization that is purposefully developed to take advantage of proven organizational theories (Laguerre, 2010). GSK is already well grounded in this regard, but moving to an eGSK requires contemplating how existing resources can be focused complimentarily on multiple objectives. Our goal should be to not interfere with existing operations or personnel, but instead to tag the new e-model on to what already works well. ICT has the ability to profoundly scale the impact value of what already exists, and it is clear that this project can be an exceptional example of multiple a bottom line ROI (GIIN, 2012). We should be able to extract from each department enough of what is needed for this eLearning experience to ensure that in the future it cannot be easily separated from the other profit-making priorities of the company. An appropriate eTeam (okay, enough of the e's!) will be created to mirror each of the critical departments; and space will be preserved for including either internal or external stakeholders who may be shown to otherwise be excluded because of our business configuration. The team will include lower- and upper management representatives, scientific professionals, operational experts, and creative representatives of stakeholder departments. HR and IT representatives will either be included and/or specialized technical expertise in these and other hands-on components will be made available to the team.

E2: Specific attention in regard to this recommendation will be directed at all of the corporate elements associated with governance, business operations, production, diversity and community/global integration now in place (GSK, 2012). We have established communication and flow diagrammatic representations of these sectors. In reviewing them, the oversight team will be guided by what already exists and will look toward integrating ICT with an eye toward making the organizational documents and flow patterns interactive to support further change.

E3: Our recommended guide for this element comes from the writings of Joshua C. Laguerre (2010) on how to develop leadership utilizing researched and philosophically grounded leadership theories. He bases his findings on Yukl's 2010 "Leadership in Organizations," which he supplements with the findings of other critically reviewed operational foundations. Laguerre chose Yukl because of his comprehensive and appealing definition of leadership, which incorporates the recognized important elements of effective leadership and was geared toward sustaining future leadership development via a dynamic or
View Full Essay

Type 1 Diabetes

Words: 1149 Length: 4 Pages Document Type: Essay Paper #: 36732156

Type 1 Diabetes

Diabetes has been among the illnesses that need rigid and proper attention to maintain the normal condition of the patient's body. Among the stages and types of diabetes, type 1 diabetes is the illness type that usually hits both the young and adults. This disease is preventable though. However, if the health condition of the patient with type 1 diabetes is not properly managed, the risk to serious complications such as heart ailments, damage in kidney and nerve, blindness, and many others, is high.

In any kind of illnesses, it is essential that one acquire enough information to prevent from getting or developing a disease. In view of this, in relation to type 1 diabetes, this paper finds it important to discuss the pathogenesis of Type 1 Diabetes. This paper aims to provide useful information on the following.

History of Type 1 Diabetes

Symptoms of Type 1…… [Read More]

Bibliography

2002). Clinical practice recommendations: 2002. Diabetes Care.

American Diabetes Association. 25, 21.

Ackinson, M.A., Wilson, S.B. (2002). Fatal Attraction: Chemokines and Type 1 Diabetes.

The Journal of Clinical Investigation, (110)11, 1611.
View Full Essay

Health Care There Are a Number of

Words: 930 Length: 2 Pages Document Type: Essay Paper #: 98514660

Health Care

There are a number of innovations that can lower the cost of health care. The first category of innovation is prevention. esearchers are studying the issue of prevention more intently, as the cost benefits of avoiding illness, or of early detection, are evident. Exploration of the human genome is particularly important in helping the health care industry in early detection, and prevention. Gene therapy and other innovations can help keep people from getting certain conditions in the first place, and when such innovations are focused on chronic conditions, they can dramatically lower the total cost of health care.

Another type of innovation that can lower the cost of health care is anything that reduces the length of stay or the invasiveness of procedures. Many such innovations, such as arthroscopic surgery, have already contributed to lowering the costs associated with certain procedures. obotics is a major player here, having…… [Read More]

References

Aamodt, M (2013). Industrial/Organizational Psychology. Wadsworth Cengage: Boston

Chaffee, J. (2012). Thinking Critically. Wadsworth Cengage: Boston.

Domoff, S., Hinman, N., Koball, A., Carhart, V., Baik, K. & Carels, R. (2012) . The effects of reality television on weight bias: An examination of The Biggest Loser. Obesity. Vol. 20 (5) 993-998.

Greenwald, H. (2010) Health Care in the United States:: Organization, Management and Policy. John Wiley & Sons: San Francisco.
View Full Essay

Eight Questions About Valuing Companies

Words: 470 Length: 3 Pages Document Type: Essay Paper #: 99546147

Investment Valuation

The value of ABV's equity per share can be calculated as follows. First, calculate the value of the operating assets, so EBITDA less the tax rate, adjusted downward for the reinvestment rate and then multiplied by the perpetual growth rate. This is then divided by the cost of capital less the growth rate:

To this, the cash should be added, the debt subtracted to get the value of the equity:

And this is divided by the number of shares 200 million, to give an earnings per share of:

If there are equity options on the shares, then those options would be subtracted from the share value. The value of the options is 50 * 5 = $250 million. This is then subtracted from the equity value above 799.90-250.00 = 599.90

And this is then divided by the number of shares outstanding

599.90 / 200 = $3.00

With the…… [Read More]

View Full Essay

Fragile X Syndrome

Words: 2837 Length: 8 Pages Document Type: Essay Paper #: 97214966

Fragile X syndrome (also called Martin -- Bell syndrome, or Escalante's syndrome) is the most common single cause of mental retardation and the second most common inherited form of mental retardation, affecting approximately 1 in 1000 males and 1 in 2000 females (Sadock & Sadock, 2007). Fragile X syndrome is the result of a single gene mutation, a mutation of the FM1 gene, located on the X chromosome. Every person has 23 pairs of chromosomes (46 individual chromosomes). Twenty two pairs of chromosomes are autosomes and one pair is an allosome, also known as sex the chromosomes. The allosomes determine the person's gender. Female infants receive two X chromosomes (one each from mother and father), whereas males receive one X chromosome (from the mother) and one Y chromosome (from the father). The site of the Fragile X mutation is on one of these X chromosomes (Sadock & Sadock, 2007).

The…… [Read More]

References

American Psychiatric Association (2000). Diagnostic and Statistical Manual of Mental

Disorders, IV- Test Revision. Washington, DC: Author.

Atkinson, R.C. & Shiffrin, R.M. (1968). Human memory: A proposed system and its control processes. In Spence, K.W & Spence, J.T. (Eds.) pp. 89 -- 195. The psychology of learning and motivation (Volume 2). New York: Academic Press.

Baddeley, A. (2003). Working memory: looking back and looking forward. Nature Reviews
View Full Essay

Edwards Syndrome Trisomy 18 8 Sources

Words: 1372 Length: 4 Pages Document Type: Essay Paper #: 77979310

Edwards Syndrome, Trisomy 18 8 sources ( 4-5 Print Sources 3-4 online Sources) All questions answered essay ( mandatory): -What ? (Discription genetic disorder) -What genes chromosomes linked disorder? -Describe populations affected Edwards Syndrome (Include gender, age & number affected USA wordwide.

Edwards syndrome which is also known as Trisomy 18 is a genetic disorder that is caused by the presence of a third copy of chromosome 18 instead of the normal two copies. The extra 18th chromosome comes as a result of nondisjunction of the chromosomal material during meiosis. As a result of failure in the segregation of a chromosome to the daughter cells, there can be errors in the meiotic division leading to an extra chromosome. This extra chromosome usually occurs before conception and it is the second most common autosomal trisomy that carries to term after Down syndrome though it is more common in females than males…… [Read More]

References

Buyse, M.L. (Ed.). (1990). Birth Defect Encyclopedia Cambridge, Massachusetts: Blackwell Scientific Publications.

Canfield, M.A., Honein, M.A., Yuskiv, N., Xing, J., Mai, C.T., Collins, J.S., . . . Kirby, R.S. (2006). National estimates and race/ethnic-specific variation of selected birth defects in the United States, 1999-2001. . 2006 Nov;76(11):747-56. Birth defects research. Part A, Clinical and molecular teratology, 76(11), 747-756.

HealthStar PR. (2012). First Peer-Reviewed Data For New Noninvasive Prenatal Test Published By Aria Diagnostics. Medical News Today. Retrieved from  http://www.medicalnewstoday.com/releases/240123.php 

Merritt, T.A., Catlin, A., Wool, C., Peverini, R., Goldstein, M., & Oshiro, B. (2012). Trisomy 18 and Trisomy 13: Treatment and Management Decisions. NeoReviews, 13(1), e40-e48. doi: 10.1542/neo.13-1-e40
View Full Essay

Genetics Option 3 Darwin's Perspective According to

Words: 1309 Length: 4 Pages Document Type: Essay Paper #: 51827752

Genetics

Option 3: Darwin's Perspective

According to Darwin, the survival of a species is determined by the degree of strength of its members. Thus, the "fittest" in terms of physical prowess as well as to a degree mental capacity survives. Human beings have long used their mental capacity to overcome the challenges of the physical environment. The very first discoveries of tools, fire and the wheel have set the species apart from the rest of life on earth. Human beings use their mental capacity to create tools in order to ensure and facilitate their survival in the face of challenges such as weather, predators and illness. From the Darwinian viewpoint, genetic engineering is simply the next step in the evolution of the human capacity to ensure the survival of their species. Some of the unforeseen results of technological advancement have admittedly been devastating, but another uniquely human capacity is accountability.…… [Read More]

Bibliography

Chartrand, Sabra. "Patents: A Human Gene Is patented as a Potential Tool Against AIDS, But Ethical Questions Remain." Human Genome Sciences Inc. (www.hgsi.com)

Ehrenreich, Barbara. "The Economics of Cloning."

Kolata, Gina. "A Clone is Born." Reprinted from: Clone: The Road to Dolly and the Path Ahead 1998.

Longstaff, Simon. "Genes for Sale."
View Full Essay

Conventional Treatment

Words: 2146 Length: 7 Pages Document Type: Essay Paper #: 77607527

Therapies Deprive Patients From Conventional Cancer Therapies

Future Ethical Prospective

Do public demand for, and clinicians' tendencies to prescribe novel targeted cancer therapies in a resource starved healthcare system deprive other patients of conventional treatment? If so, can it be justified?

Over the years, there have been several studies which have shown that a small but noteworthy fraction of cancer patients drop one or more conventional cancer treatments and use novel targeted cancer therapies instead. When it comes to recent public demands in healthcare, research into cancer control has addressed issues relevant to novel targeted cancer therapies in a resource starved healthcare system. Disparities have been addressed to a much greater degree than before, with studies of the conventional treatment of cancer especially in our variety of ethnic and socioeconomic settings. Conventional treatment have a greater social impact and the demand for such treatments of many (male and female) of…… [Read More]

References:

Borja-Cacho, D.J.E.H.S.A.K.B.D.J. & V.S.M., 2008. Molecular targeted therapies for pancreatic cancer.. The American Journal of Surgery, 196(3), p. 430.

Garvalov, B.K. & A.T., 2011. Cancer stem cells: A new framework for the design of tumor therapies.. Journal of Molecular Medicine, 89(2), pp. 95-107..

Kim, J.A., 2003. Targeted therapies for the treatment of cancer. The American Journal of Surgery, 186(3), pp. 264-8.

Kundu, S.K. & N.M., 2012. Targeted therapy in head and neck cancer.. Tumor Biology, 33(3), pp. 707-21.
View Full Essay

Von Hippel-Lindau Von Hippel Lindau Disease Von

Words: 2314 Length: 8 Pages Document Type: Essay Paper #: 45262901

Von Hippel-Lindau

Von Hippel Lindau Disease

Von Hippel-Lindau Disease

Von Hippel-Lindau Disease

Von Hippel-Lindau Disease

The von Hippel-Lindau, also known by its synonyms, familial angiomatosis cerebeloretinal, hemangioblastomatosis or retinal and cerebellar angiofacomatosis, is the abnormal growth of retinal- cerebellar vessels, and is classified as a rare disease of autosomal dominant hereditary character, within the group of phacomatosis. The disease was described by two independent groups, led by Eugen von Hippel (1904) and Arvid Lindau (1927). The cause of the disease is the mutation of both alleles of the VHL group, the one caused by genetic factors, and the second after a de novo mutation. The von Hippel-Lindau syndrome is considered by increased tendency to kidney tumors, central nervous system, including the cerebellum, and by affecting the retina. At the moment, no medical treatment is present for curing this disease, but knowledge of their symptoms and possible genetic research currently makes…… [Read More]

References

He's FJ, Hoppener JW, Lips CJ (2003). Clinical review 155: pheochromocytoma in Von Hippel-Lindau disease. J Clin Endocrinol Metab; 88: 969 -- 974.

Johnston LB, Chew SL, Trainer PJ, Reznek R, Grossman AB, Besser GM, Monson JP, Savage MO (2000). Screening children at risk of developing inherited endocrine neoplasia syndromes. Clin Endocrinol (Oxf); 52: 127 -- 136.

Lindau A (1927). On the question of angiomatosis retinae and your brain complicatio. Acta Ophthalmol; 4: 193 -- 226.

Lonser R, Glenn G, Walther M, Chew EY, Libutti SK, Linehan WM, et al. (2003). Von Hippel-Lindau disease. Lancet;361:2059-67.
View Full Essay

Colorectal Cancer the Gastrointestinal Tract

Words: 2490 Length: 9 Pages Document Type: Essay Paper #: 3623909

Tobacco use or cigarette smoking is also linked to the development of colorectal cancers most especially after more than 35 years of smoking. but, there is no biological explanation for this link.

Colorectal cancer is often incidentally found in screening procedures and may be completely asymptomatic. ut approximately half of patients with colorectal carcinoma experience abdominal pain, this is the most common symptom. About 35% of patients have altered bowel habits, 30% with occult bleeding, and 15% with intestinal obstruction. For right-sided colon cancers, there is a tendency that they are larger and more likely to bleed, whereas left-sided tumors tend to be smaller and more likely to be obstructing.

Presenting symptoms of Colorectal Cancer vary with the anatomic location for the tumor. Stool is generally liquid and passes through the ileocecal valve into the right colon. Cancers arising in the cecum and ascending colon may become quite large but…… [Read More]

Braunwalk, et. al.. "Harrison's Principles of Internal Medicine." 15th ed., McGraw Hill, Vol.1, pg 581-586, 2001.

University of Missouri. "Anatomy and Function of the Gastrointestinal Tract" Health Care, 2008. May 9, 2008 http://www.muhealth.org/weightlosssurgery/anatomy.shtml

Wafik S. El-Deiry, MD, PhD. "Colon Cancer, Adenocarcinoma," eMedicine, Oct 11, 2006. May 9, 2008 http://www.emedicine.com/med/topic413.htm www.medicinenet.com/script/main/art.asp?articlekey=6915"Dennis Lee, MD. "Colon Cancer Screening and Surveillance," MedicineNet.com, March 25, 2005. May 9, 2008.  http://www.medicinenet.com/colon_cancer_screening/article.htm
View Full Essay

Theory of Using Vitamin a As Treatment for Autism Spectrum Disorders

Words: 1547 Length: 4 Pages Document Type: Essay Paper #: 67763224

Vitamin a for Autism Spectrum Disorder

The Theory of Using Vitamin a as Treatment for Autism Spectrum Disorders

There is widespread linkage of Autism Spectrum Disorders (ASD) and Oxytoxin. There are reports that any decrease in the pathway of Oxytocin, is a possible causative factor to the development of autistic situation (Munese-et-al., 2008). Decrease in Oxytocin comes about because of mutations in its receptors, which lead to a reduction on the amount of Oxytocin released to the body posing possible chances for the development of autistic conditions (Lerer et-al., 2008). There is partial dependency of Oxytocin secretion to a protein found, in the cellular membranes of certain red blood cells. The scientific reference of these proteins is CD38, and whenever they mutate there develops a risk of Autism. Mice engineered without the oxytocin receptor gene have been shown to display socially anomalous behavior such as a deficiency of maternal behavior…… [Read More]

References

Andari-et-al. (2009). Promoting social behavior with oxytocin in high functioning autism spectrum disorders Department of Psychiatry 1-6

Ebstein R., Mankuta D. Yirmiya N., Maravasi F. (2011). Are retonoids potential therapeutic agents in disorders of social cognitions including Autism. EEBS letters: journal homepage. 1529-1536

Campbell et-al. (2010). Association of oxytocin receptor (OXTR) gene variants with multiple phenotype domains of autism spectrum disorder J. Neurodevelop Disord 101-112

Higashida H., Kikuchi M., Yokoyama S., Munesue T. (2012). CD38 and its role in Oxytocin secretion and social behavior Hormones and behavior journal homepage 351-358
View Full Essay

Krabbe Disease Also Known as

Words: 1669 Length: 4 Pages Document Type: Essay Paper #: 11188228

Though there are state laws and federal laws that militate against discrimination at any levels, the application of this law is a challenge and the patients end up being discriminated against anyway. The victims will most likely end up in nursing homes where they will receive treatment but this separates them from the family life.

The other factor is the cost that weighs down the concerned people in terms of medical bills. It is a disease that is expensive to manage since there are numerous scans that one must get and the cost of specialized care doesn't make it any better. The good news however is that there are several organizations that have volunteered to help the victims of this disease like Hunters Hope (2009) which was purposefully formed to cater for patients of the disease in terms of support and information among many other organizations.

Reference

Alexander C. Guo,…… [Read More]

U.S National Library of Medicine (2011). Krabbe Disease. Retrieved April, 11, 2011 from http://ghr.nlm.nih.gov/condition/krabbe-disease

University of Maryland Medical Center (2009). Krabbe disease - Overview . Retrieved April, 11,

2011 from http://www.umm.edu/ency/article/001198.htm
View Full Essay

Histone H2AX in the Study

Words: 5478 Length: 15 Pages Document Type: Essay Paper #: 64159440

These proteins include homologous members of yeast. The presences of these proteins suggest that E. histolytica is skilled to perform homologous recombination, which is the same as in other organisms. DNA damage was evaluated by TUNEL assay. In yeast and in human cells, histone H2AX becomes rapidly phosphorylated when DSs are introduced into chromatin (Lavi et al.).

Studies show that histone as a protein plays a significant role in the transition between the expression of a fetal gene and that of the adult gene. The adult gene's metabolism becomes oxidative in order to adapt to air and to weight, as it generates methylated transmitters and creatine phosphate. The muscles get used to life on the ground as compared to the fetal life which takes place in an aquatic environment. Regulated proteins allow the muscles to respond in a more adequate manner to this environment.

Now, let us see how histone…… [Read More]

Bibliography

Abraham, R.T. (2001). "Cell cycle checkpoint signaling through the ATM and ATR kinases." Genes Dev 15(17): 2177-96.

Alexiadis, V., T. Waldmann, J. Andersen, M. Mann, R. Knippers and C. CGruss (2000). "The protein encoded by the proto-oncogene DEK changes the topology of chromatin and reduces the efficiency of DNA replication in a chromatin-specific manner." Genes Dev 14(11): 1308-12.

Aten, R. And H. Behrman (1989). Antigonadotropic effects of bovine ovarian gonadotropin-releasing hormone-binding inhibitor from bovine ovaries. Purification and identification of histone H2A. J. Biol. Chem. 264: 11065-11071.

Antigonadotropic effects of bovine ovarian gonadotropin-releasing hormone-binding inhibitor/histone H2A in rat luteal and granulosal cells. J. Biol. Chem. 264: 11072-11075.
View Full Essay

DNA Sequence

Words: 1160 Length: 4 Pages Document Type: Essay Paper #: 27995635

human DNA sequence composed of a series of letters such as 'accagacagt' and the objective was to decipher this jumble of letters and interpret the results. I suppose I should report that the process went smoothly and that after a bit of research I now consider myself an expert in regard to the new science of DNA Sequencing. However, I have a thousand more questions now than before I began and even the answers I came up with may or may not be correct. I do know for a fact that this is a pretty new art or science and its potential seems limitless. "DNA itself has thus far shown only modest evidence of possessing any intrinsic catalytic activities, although the prospect that more will be discovered in the future is surely plausible." (Cantor & Smith, 1999, xv)

The internet has made so many sites and processes available to the…… [Read More]

Obviously, enterokinase gene being tied to this chromosome entails a great deal of research interest into the biological functions of the gene and the manner by which it contributes to disease. Defects in PRSS7 therefore are a direct cause of enterokinase deficiency which is a life-threatening intestinal malabsorption disorder. The disorder can be characterized by severe bouts of diarrhea and failure to thrive and thus create a situation of initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase a).

Animals, like humans, have to handle digestion of exogenous macromolecules without destroying endogenous constituents so the serine protease or enterokinase seems to be a fundamental digestive system requirement. In other words, all vertebrates such as mice or dogs have adapted a two step enzymatic cascade that is used to change pancreatic zymogens over to active enzymes in the lumen of the gut as discovered by researchers in Pavlov's laboratory in the early 1900's. "Extracts of the proximal small intestine were shown strikingly to activate the latent hydrolytic enzymes in pancreatic fluid. Pavlov considered this intestinal factor to be an enzyme that activated other enzymes, or a 'ferment of ferments' and named it enterokinase." (Stone, 2002)

Prospects For
View Full Essay

Psychopathology Understanding of Psychopathology Psychopathology Has Had

Words: 2785 Length: 9 Pages Document Type: Essay Paper #: 7904372

Psychopathology

Understanding of psychopathology

Psychopathology has had differentiated opinions from variant psychologists. Warner's opinion of relabeling people's process and Prouty's therapy that offers a mentally unwell person are both discussed in depth for better understanding. Also, the effects of language barrier to collaborating psychologists and psychiatrists in dealing with person-centered therapies have been reviewed in this article. Communication enhancement is fundamental for the relaying of information between the different medical practitioners is what will help in the scientific research on matters dealing with brain functionality, and the enhancement of methods to counter the dysfunctional elements in human ability. This paper aims at examining closely the person-centered approach, and its efficiency in dealing with the brain disorders and other physical impairments.

Psychopathology is a study that deals with behaviors, human feelings and thoughts that either causes depression or anxiety (distress), forces one to indulge in dangerous activities, which can be against…… [Read More]

References

Allan, H.F., 2000. Where Have All The Abnormal People Gone? Humanist Journal, Vol. 60, Issue 2, p. 29.

Eldin, G. And Golanty, E., 2009. Health and Wellness. New York: Jones and Bartlett Learning.

Joseph, S. And Worsley, R. ed., 2007. Person-centered Practice. Herefordshire: PCCS Books.

Joseph, S., 2006. Person-centered Coaching Psychology: A Meta-theoretical Perspective. International Coaching Psychology Review, Volume 1, Number 1.
View Full Essay

Polydactylism Polydactyly Is a Relatively

Words: 2143 Length: 6 Pages Document Type: Essay Paper #: 14456156

This would clearly be preferable to performing surgery, but may be more applicable in cases of type B than type a polydactyly. Of a total of 21 cases which were examined, this procedure resulted in a slight complication in only one case, where the digit had to be removed surgically due to failure of removal by suture ligation. The only real side effect of this simple treatment is that there was found to be a small bump remaining at the site in 43% of cases.

Conclusion

Although there has been some work into the genetic basis of polydactyly, advances in examination of the human genome may create a better understanding of the condition in the future. A large amount of the work done so far has been focused on animal models, and there is still room for further work to discover the genetic basis of the different types of polydactyly…… [Read More]

References

Ataru, S., Park, S. & Ryo, Y. (2005). Surgical treatment for lateral ray polydactyly of the foot: Toe selection and interdigital space reconstruction using a planter flap. Japanese Journal of Plastic & Reconstructive Surgery, 48(2): 155-159.

Boeing, M., Cassia F. Paiva, L., Lima Garcias, G., Graca Martino Roth, M. & Santos, I.S. (2001). Epidemiologia das polidactilias: Um estudo de casos e controles na populacao de Pelotas-RS. Journal de Pediatria, 77(2); d.o.i.: 10.1590/S0021-7557200100017.

Borisch, N., Stunitz, B. & Blauth, W. (1995). Case histories surgical treatment of polydactyl of the little toe involving proximal and middle phalanx. Orthopedics and Traumatology, 4(4): 246-253.

Gurnett, C.A., Bowcock, a.M., Dietz, F.R., Morcuende, J.A., Murray, J.C. & Dobbs, M.B. (2007). Two novel point mutations in the long-range SHH enhancer in three families with triphalangeal thumb and preaxial polydactyly. American Journal of Medical Genetics, 143(1): 27-32.
View Full Essay

Cellular Proliferation Cancer One-60-Year-Old Might

Words: 1326 Length: 4 Pages Document Type: Essay Paper #: 23453679

Immunotherapists can provide sensitive and accurate cancer diagnostic tools for the successful treatment of the disease and to stop it well in its tracks (cancerresearch.org, 2009). The outward advantages of immunotherapy are as follows: certain drugs have fewer side effects and offer patients a higher quality of life, bolstered anti-cancer effectiveness and rates of survival, benefits are often reaped quickly for the patient (cisncancer.org). The disadvantages are as follows: some varieties of this treatment have serious side effects, are very expensive and occasionally offer just a short-term efficacy (cisncancer.org)

5. An overexpression of proto-oncogenes can cause cancer as mutated forms of these genes can promote unrestrained cell proliferation: "oncogenes actively promote proliferation (analogous to the gas pedal of the cell cycle). Mutations that convert proto-oncogenes to oncogenes typically increase the activity" (Hyland). An underexpression of tumor suppressor genes can also put an individual in a precarious situation. Tumor suppressor genes…… [Read More]

References

Cancer.gov. (n.d.). Understanding Cancer Series. Retrieved from Cancer.gov: http://www.cancer.gov/cancertopics/understandingcancer/cancergenomics/AllPages

Cancer.gov/topics. (n.d.). Tumor Markers. Retrieved from Cancer.gov: http://www.cancer.gov/cancertopics/factsheet/detection/tumor-markers

Cancer.org. (n.d.). Tumor Markers. Retrieved from Cancer.org: http://www.cancer.org/Treatment/UnderstandingYourDiagnosis/ExamsandTestDescriptions/TumorMarkers/tumor-markers-common-ca-and-t-m

Cancerresearch.org. (n.d.). Cancer and the Immune System: Advantages of Cancer Immunotherapy. Retrieved from Cancerresearch.org: http://www.cancerresearch.org/resources/cancer-immune-system/cancer-immunotherapy-advantages.html