Cracking and Protecting My Genetic Code
Cracking Your Genetic Code
Genetics has advanced to the point that it is inevitable that genotyping services will become commonplace and increasingly inexpensive, unless legislatures take action to limit the public's access to this information. Since genotyping services are essentially businesses catering to the public and providers of medical services, an issue about quality and the relevance of findings becomes important. Near the beginning of the Nova film Cracking Your Genetic Code, the filmmakers introduce the topic about whether the public should have access to their own genetic information without the need of getting a doctor's permission. There are obvious merits to this concern, especially in light of how customers will interpret the statistical results.
The dangers inherent to receiving genetic information in the form of probabilities are that a customer will not understand the significance of a result and will fall prey to over-interpretations that some…...
cheap genomic sequencing has widespread and unforeseen cultural, political, and societal implications that have only just begun to reverberate through the human population at large. Genomic sequencing not only reveals some of the causes and connections behind certain diseases or disorders, but also puts the lie to certain forms of bigotry which assumed that dramatic phenotypic differences represented a similarly dramatic genetic or biological difference (put another way, genome sequencing reveals just how little skin color says about a person). The implications of full genome sequencing can largely be broken down into a few distinct but related categories, including healthcare, notions of race and ethnicity, and social and criminal justice. Examining the use of genetic information with an eye to these categories reveals not only the implications of genomic sequencing for society at large, but also how it may affect minorities and those wishing to protect their right to…...
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References
Acem, E. (2007). Legal expertise, scientific knowledge, and medical ethics at a crossroads.
Canadian Journal of Law and Society, 22(2), 231-241.
Lindsay, R.A. (2005). Enhancements and justice: problems in determining the requirements of justice in a genetically transformed society. Kennedy Institute of Ethics Journal, 15(1), 3-
Genetic screening is one of the most controversial topics in the scientific arena today. The advent of the Human Genome Project, which maps the complete human genetic code, has brought this issue to the forefront. This paper will discuss the basic science that underlies genetic screening, applications of genetic screening, and investigate some of the common misconceptions and ethical questions about its use.
Genetic screening itself is simply "the systematic search within a population for persons possessing particular genotypes, which are either associated with disease, predisposing to disease, or leading to disease in descendants" (Miller). In simpler terms, genetic screening involves testing and determining whether "an individual's genetic material to predict present or future disability or disease either for oneself or one's offspring" (McCarrick). Essentially, genetic screening is conducted for several basic reasons, including the care of the ill and the prevention of disease, providing reproductive information, determining the incidence of…...
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Works Cited
Alberts, Bruce. 2002. Molecular biology of the cell, 4th ed. New York: Garland Science.
McCarrick, Pat Milmoe. 1993.Genetic Testing and Genetic Screening. Scope Note 22. National Reference Center for Bioethics Literature, Georgetown University, 1993. Kennedy Institute of Ethics Journal (KIEJ), Reprinted September 1993, 17 p. (Last updated February 2002). 07 May 2004. http://www.georgetown.edu/research/nrcbl/scopenotes/sn22.html
The following images show certain disorders that result due to mutation. Children born from the same family members' shows higher similarity index regarding the genetic disorder number inclusive of the Indian community (Cummings, 2010, pg 333).
Curbing gene disorders
Stoppage of varying types of disorders is possible through learning in consideration of human development the number of genes contained in a single genome, their respective location and the establishment of functions or roles in the various genetic processes. This is achievable through strategized genetic mapping, where the establishment of specified genes having same linkage involved. The mapping establishes the respective linkages between genes and as a result of their location in the same gene, the crossing over frequency with the existing distance amid them is notable (Cummings, 2010, pg 333). esearch on the various risks factors involved can also be considerable as beneficial. This enables the development of certain preventive measures…...
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References
Benson, B. (2012). Advances in Child Development. London: Academic Press.
Bowden, V.G. (2009). Children and Their Families. Atlanta: Lippincott Williams and Wilkins.
Cummings, M. (2010). Human Heridity; Principles and Issues. New York: Cengage Learning.
To elaborate, he used his 'transistor' to build logic circuits that program each cell's behavior. For instance, he was able to tell a cell to change color in the presence of both a specified two enzymes. Remarked Kleem (online): "Endy envisions plant-based environmental monitors, programmed tissues and even medical devices that "make Fantastic Voyage come true," (Kleem, 04.02.13).
In the first (grainy) image below, Endy's DNA "buffer gates" flash different colors according to their situation. In the image below that, we have a string of DNA -- we see the code of the a's, C's, T's and G's -- that has been programmed by synthetic biologist Eric Winfree of the California Institute of Technology --.
(Excerpted from Keim, B Computers Made Out of DNA, lime and Other trange tuff
Transcription is a process that genetic information on the DNA copies into NA and the DNA acts as the template for the new molecules of NA. Transcription process begins with the DNA double helix unwinding as the hydrogen bonds holding the opposing bases breaks and the DNA strands are uncoupled. The process occurs within the cytoplasm of a prokaryote and in the nucleus of eukaryotic cells. Transcription process consists of three steps; initiation, elongation, termination, and are regulated by transcription factors that include protein products of the genes. The protein products regulate at postranscriptional levels every time.
Initiation of transcription begins with enzyme NA polymerase that identifies and attaches to DNA at the promoter and transcription of the DNA template starts. An initiation complex forms by association of 50 proteins different from each other required by NA polymerase II. NA polymerase synthesizes polynucleotides of NA from the template of DNA.…...
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References
Latchman, D. (2009). Eukoryotic Transcription Process. New York: Cengage Learning.
Alvis, F. (2010). New Approach to Translation Process. Chicago: Chicago University Press.
Singer, M. (2011). Genes and Genomes. New York: Cengage Learning.
Campbell, M. (2009). Biochemistry. London: Oxford University Press.
Heather D's decision not to be tested for the Huntington's gene a wise one?
Heather D's decision not to be tested for Huntington's is unwise given that Heather is about to become a mother. If she develops the disease, this could significantly impair her ability to parent a child. She should make provisions for the child if she has the mutation and should discuss the situation with her husband. The genetic test for Huntington's is not a test that merely indicates a tendency or a likelihood of developing the debilitating condition -- because of the fairly narrow chromosomal area affected by the mutation, scientists can predict with a great degree of certainty who will or who will not develop the disorder (579).
Q2. Does the genetic counselor's suggestion provide a satisfactory solution to the problem?
No. Most individuals who are opposed to abortion also view the termination of fertilized embryos outside of…...
Huntington's disease (HD) was the first autonomic dominant disorder for which genetic prediction became possible" (Harper, et al., 2000, Journal of Medical Genetics, p. 567). HD is a disease that occurs due to an inherited disorder leading to the death of brain cells. A diagnosis of HD is accomplished through genetic testing which can be implemented at any age regardless of whether the symptoms manifest or not. Although, the specific symptoms vary between people, nevertheless, symptoms can start with people between 35 and 45 years of age and can also start in some individuals at even anearlier age. The disease may affect successive generations if health interventions are not implemented (Mandel, 2016).
Additionally, "the cause of HD is due to a dominant mutation of autosomal form of the gene called Huntington. This shows that a child born by an affected person has a 50% chance of developing or inheriting the disease"…...
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References
Causes and risk factors. (2016). Health Communities. Retrieved from healthcommunities.com/huntingtons-disease/cause.shtml.http://www.
Denbo, S. M. (2013, January 1). Balancing the rights of children, parents and the state: The legal, ethical and psychological implications of genetic testing in children. Southern Journal of Business and Ethics, 5, 188-190.
Domaradzki, J. (2015, January 1). Lay constructions of genetic risk. A case-study of the Polish Society of Huntington's Disease. Polish Sociological Review, 189, 107-111.
Draper, B. (2004). Dealing with dementia: A Guide to Alzheimer's Disease and other dementias. Crows Nest, NSW: Allen & Unwin.
Noncoding DNA, also known as "junk DNA" describes portions of the DNA sequence that do not appear to have any presentable use -- they do not encode for proteins, etc. In fact, in a most eukaryote cells, a rather large percentage of the total genome is noncoding DNA, but this varies between species. However, it is now a misnomer to call this material "junk," because the more sophisticated we become at biochemistry, we find that many do have subtle biological functions, including the transcriptional and translational regulation of certain protein-coding sequences. esearchers also belive that other noncoding sequences have a likely, but unconfirmed function, as an inference from high levels of inherited tratis and natural selection processes (Masters, 2005, 163-5).
esearchers know that the amount of genomic DNA varies widely between organisms, as does the proportion of coding and non-coding DNA within these genomes. For instance, 98% of the human genome…...
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REFERENCES:
Barrows, E. (2001). Animal Behavior Desk Reference. Boca Raton, FL: CRC Press.
Mueller, Guo and Ayala. (1991). Density Dependent natural Selction and Trade-Offs in Life History Traits. Science, 253(1), 433-35.
Ricklefs and Whiles. (2007). The Economy of Nature: Data Analysis Update. New York: Macmillan.
technology has revolutionized society: communication, transportation, commerce, and especially medicine. . Ironically, for centuries and still in Oriental Medicine, healthcare was and is tailored to the individual. Even the Greek Physician Hippocrates wrote that he prescribed sweet elixirs to some and astringents to others depending on their individual condition (Pray, 2008). 21st century medicine, though, is more about an individual person's genetic code, and is made possible by advances in genetic technology and engineering. This is partially due to the Human Genome Project, a massive program completed in 2003 that focused on the identification of the individual genes that make up human DNA with the overall hope that it would initiate genomic medicine -- healthcare delivered based on the individual's medical history and genetic profile (About the Human Genome Project, 2011). Traditionally, medicine diagnoses human illnesses based on quantitative and qualitative signs and symptoms. With the advent of genetic…...
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References
About the Human Genome Project. (2011, September 19). Human Genome Management Information Systems. Retrieved from: / Human_Genome/project/about.shtmlhttp://www.ornl.gov/sci/techresources
Through the maintenance of proper scientific and ethical standards, the knowledge gained from this research could revolutionize the field of criminal justice and public rehabilitative systems.
eferences
Lowenstein, L. (2003). "The Genetic Aspects of Criminality." Journal of Human Behavior in the Social Environment 8(1), pp. 63-78.
Peele, S. & DeGrandpre, . (1995). "My genes made me do it." Psychology today 28(4), pp. 50-7.
Pieri, E. & Levitt, M. (2008). "isky individuals and the politics of genetic research into aggressiveness and violence." Bioethics 22(9), pp. 509-18.
eif, A.; osler, M.; Freitag, C.; Schneider, M.; Eujen, M.; Kissling, C.; Wenzler, D.; Jacob, C.; etz-Junging, O.; Thome, J.; Lesch, K. & etz, W. (2007). "Nature and Nurture Predispose to Violent Behavior: Serotonergic Genes and Adverse Childhood Environment." Neuropsychopharmacology 32(11). pp. 2375-83.
eitz, W.; eitz-Junginger, P.; Supprian, T.; Thorne, J. & osler, M. (2004). "Association of serotonin transporter promoter gene polymorphism with violence: relation with personality disorders, impulsivity, and…...
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References
Lowenstein, L. (2003). "The Genetic Aspects of Criminality." Journal of Human Behavior in the Social Environment 8(1), pp. 63-78.
Peele, S. & DeGrandpre, R. (1995). "My genes made me do it." Psychology today 28(4), pp. 50-7.
Pieri, E. & Levitt, M. (2008). "Risky individuals and the politics of genetic research into aggressiveness and violence." Bioethics 22(9), pp. 509-18.
Reif, A.; Rosler, M.; Freitag, C.; Schneider, M.; Eujen, M.; Kissling, C.; Wenzler, D.; Jacob, C.; Retz-Junging, O.; Thome, J.; Lesch, K. & Retz, W. (2007). "Nature and Nurture Predispose to Violent Behavior: Serotonergic Genes and Adverse Childhood Environment." Neuropsychopharmacology 32(11). pp. 2375-83.
Ian Wimut and Keith Campell could effectively clone two sheeps named Megan and Morag in July 1995 from the differentiated emryo cells. (History of Cloning)
Dolly originated on July 5, 1996 as the first organism ever to e cloned from adult cells. Following the announcements for creation of Dolly y Ian Wilmut, an extensive deate on human cloning ethics emerged and that led President Clinton to propose for a five-year moratorium on federal as well as privately invested human cloning research on March 4, 1997. Richard Seed, a Havard graduate could announce on Decemer 5, 1997 aout his ojective of cloning a human eing prior to an of the process y enactment of the federal laws. Following the successful cloning of Dolly, Ian Wilmut and Keith Campell generated Polly, after cloning of a Poll Dorset lam from skill cells grown on a la and with its alteration genetically to incorporate…...
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bibliography_pages/cloning.html. Accessed on 11 March, 2005
Cloning Fact Sheet" Human Genome Project Information. Retrieved at
Jungsik Yoo
At times, marvel how far have come. Ever since was a young boy, under the influence of my father, a molecular biologist, dreamed of researching genetically inherited diseases. Today, live that reality in my current field of work and research as a graduate student in neuroscience.
Thus, long before most children, because of my early exposure to the field of biology, was intimately aware that one's genetic inheritance could determine an individual's future physical and emotional health. Perhaps it comes as no surprise that soon decided was genetically coded to become a medical researcher. will receive my Ph D. n the summer of 2006 in neuroscience. But my current studies in the field of genetics have also soberly reminded me of how far both my own learning and the field of genetics need to be stretched, before the objectives of genetic…...
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I have concluded that the hands-on clinical experience only provided by a medical school education is necessary for me to fulfill the essential experiential element that is crucial to my future desired knowledge base and scope of research. Only medical school will provide me with critical experience that will give my research the desired added practical and human value.
At the end of my education, I hope to become a research doctor who combines clinical research in his study of genetic diseases. I seek to provide the science of genetics with a human face for it is, ultimately, the study of the human body, mind, and 'wiring' in the form of the human genetic code. I been the recipient of a 'Sensory Neuroscience Training Grant '(SNTG) fellowship funded by National institute of health (NIH) since the fall of 2004. Thus I am well aware of the critical role genetics plays in public health of the nation as well as of the field of medical science, because of this generous grant, and I will strive to add to this knowledge in all of my future research.
Also, as a T.A. over the past two years, I have gleaned further knowledge of the curiosity of students for 'in the field' research. I have been grateful to have this human element present even in my PhD education. I am also proud to say I have not merely have received excellent reviews from my students, but joined them in many intramural soccer games, one of my favorite pursuits of my college years. I was not given the genetic gift, sadly, of becoming a great sports star, but I do believe that it is encoded in my own personal biology to bring a vital element of clinical humanity to the important work being done in the field of genetic research.
Environmental Influences, Domain Specificity, and Heterozygous Potential:
Environmental influences have also contributed profoundly to human sexual behavior, which becomes particularly evident when one examines certain statistical tendencies pertaining to both conscious and unconscious choices in female mate selection (Gerrig & Zimbardo 2005). As is the case with many sexually reproducing organisms, human females have evolved a marked preference for both physical and behavioral male traits consistent with the ability to provide physical protection and to garner both natural and social resources. Females of many species prefer male suitors who display characteristics such as large relative body size, robustness, good health, and those suggesting physical strength, aggressiveness, and leadership (Margulis & Sagan 1999).
Whereas some of those traits are observable externally (such as relative size), others are imperceptible on any conscious level. This is particularly true as regards heterozygous potential conducive to healthy offspring, such as the marked unconscious preference demonstrated by human…...
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References
Ackerman, D. (1995) a Natural History of Love.
New York: Vintage
Barash, D.P., Lipton, J.E. (2001) the Myth of Monogamy.
Harvard college's "oncomouse," which is a mouse that has been genetically engineered to make it more susceptible to cancer, and thus of more use in research, could be patented under Canadian patent law. The Patent Examiner refused to grant the patent, stating that higher life forms were not inventions under the applicable law because they were not compositions of matter. The majority opinion upheld the Patent Examiner's decision. Justice Binnie dissented to the majority's opinion. Justice Bastarache wrote the majority opinion.
The majority opinion, authored by Justice Bastarache represents the court's actual decision. Majority opinions represent the decision of the court. In some cases, there is no actual majority opinion because of partial dissents and concurrences, but that is not applicable in this case. The majority felt that Parliament did not intend for every conceivable subject matter to be patentable, and points to the fact that Parliament wrote an exhaustive…...
There are many different subtopics that could be addressed in an essay about genetics and heredity, from evolution to the nature versus nurture debate. Here are some catchy titles we thought of for some of those essays:
Unlocking Your Genetic Code
Genes to Genomes
Two Sides of the Same Coin: Heredity and Evolution
Genetic Expression: How Heredity Means It Can Be Nature and Nurture
The Role of RNA in Genetic Expression
Recessive Traits: Beyond Mendel’s Pea Experiments
Kissing Cousins: Exploring the Genetic Reasons for Cultural Taboos Against Incest
Humans as Mutants: The Creation of the Homo Sapien
Selective Breeding in Humans: Science Fiction or....
1. The role of ethics in scientific research: how can scientists ensure that their work is conducted ethically and with respect for human and animal subjects?
2. The impact of technology on the environment: are advancements in technology helping or harming our planet in the long run?
3. The intersection of science and religion: can these two belief systems coexist peacefully, or are they fundamentally incompatible?
4. The ethics of genetic engineering: should we be manipulating the genetic code of living organisms, and if so, what are the potential consequences?
5. The future of space exploration: what are the challenges and opportunities facing humanity....
In conclusion, the application of site-directed mutagenesis to study the effects of single base changes in the N-terminus of histone H4 has proven to be an invaluable tool in the realm of molecular biology. This technique allows researchers to pinpoint the functional significance of specific amino acids within histones, which are crucial for the structural integrity and regulatory functions of nucleosomes. By altering these amino acids, scientists can observe how these changes influence gene expression, chromatin structure, and ultimately, cellular function. The insights gained from such studies not only enhance our understanding of the basic mechanisms of gene regulation but....
Inheritance refers to the process by which traits and characteristics are passed down from parents to their offspring. This is primarily achieved through the transfer of genetic material, known as genes, from one generation to the next.
Genes are located in specific regions on chromosomes within cells. Each gene contains the instructions for a specific trait or characteristic, such as eye color or height. Offspring inherit a combination of genes from both parents, resulting in a unique set of traits and characteristics.
During the process of reproduction, genetic material is passed down from parents to offspring through the formation of sex cells....
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