Sickle Cell Disease Is a

[Harvard University] it is observed that younger patients are much better than adults in post transplantation recovery and Current statistics project a more successful picture with a reduced mortality rate for bone marrow transplantation at 5%. Also, this is a relatively new procedure with a total of only 200 people with the sickle cell disease having undergone it. [Debby Golonka]

Gene Therapy

With the advancements in genetic science the search for a cure to sickle cell disease by way of gene therapy is ongoing. It has been many years since researchers cloned the beta globin gene and current research is focused on the locus control region and the use of adeno-associated viruses as vectors. Research is also focused on inserting the AAV into pluripotent stem cells so as to trigger the synthesis of healthy beta-globin naturally. However, there are still a lot of biomolecular mechanisms involved that need to be…… [Read More]

Sickle Cell Disease or Sickle

This is often associated with an infection by Parvovirus B-19. The bone marrow's replacement of the cells is disrupted. This usually manifests with a rapid drop in hemoglobin levels. Luckily, this condition is usually self limited, and the treatment is mostly supportive. ecovery is usually heralded by an increase in the reticulocyte count.

In children and in adolescents, sickle cell disease causes growth retardation, a delay in the manifestation of secondary sexual characteristics and sexual maturation, and usually results in the child being significantly underweight. It often happens in childhood that the spleen enlarges, especially in the first year of life, resulting from the sequestration of a large number of sickled cells within the spleen. This is a painful process. The spleen will then have repeated infarcts, and splenic function is impaired during the enlargement. Eventually, the repeated episodes of infarct leave the spleen fibrotic and it shrinks in size,…… [Read More]

Sickle Cell the Outcome of

The use of hydroxyurea and postoperative heparin prophylaxes were also included in the recorded observations made by the researchers. Standard statistical techniques including regression analysis were used to determine the levels of correlation that existed between transfusion therapy, pharmaceutical use, and complications.

Materials

As this was a retrospective study that did not involve any direct experimentation or even direct observation, the materials used were rather minimal compared to many other clinical surveys. Patient records formed the entirety of the research materials used; these were accessed in accordance with privacy laws and ethical standards for the use of private medical information, with the records rendered anonymous prior to primary research being conducted and with full hospital permission. ecords were accessed primarily electronically, though hard copies of the seventy-five case histories actually used as subjects in the study were also obtained after having been sanitized of identifying information.

Materials used in analysis…… [Read More]

Sickle Cell Retinopathy Sickle Cell

Variations of this technique include scatter photocoagulation and feeder vessel photocoagulation. Scatter photocoagulation is efficacious in the treatment for sea fan lesions. The desired outcome of this therapy is extraretinal fibroneovascular tissue regression. Localized scatter photocoagulation treats early proliferative changes. Once neovascularization invades the vitreous, localized scatter photocoagulation is generally less effective. If this technique does not result in regression of proliferative changes, feeder vessel photocoagulation may be used as an adjunct to induce infarction to the remaining sea fans.

Feeder vessel photocoagulation

Obliterating feeder vessels by retinal photocoagulation causes infarction of peripheral neovascular beds. This technique manages proliferative sickle retinopathy effectively, especially in cases where neovascularization persists after extensive scatter photocoagulation treatment 6. Feeder vessel photocoagulation is often complicated by vitreous hemorrhage, retinal detachments, choroidal ischemia, choroidal neovascularization, subretinal hemorrhage and/or fibrosis, or macular pucker and hole formation.

etinal cryotherapy

etinal cryotherapy is useful in treating peripheral retinal ischemia…… [Read More]

Sickle Cell What Detracted or Hindered Participants

Sickle Cell

What detracted or hindered participants from successfully completing the activity?

When viewing many of the team building, universal collaboration significantly hindered team performance. When performed alone, many participants performed particularly well. For example, in activity 4, participants that ran through the jump rope alone, did so with little trouble. However, when required to move in unison as a team, each member had to account for the others strengths and deficiencies. When looking at the video, some teams seemed disoriented when participating as they did not collaborate with one another. As the teams became larger throughout the activity, the complications regarding collaboration were exacerbated to the point that some teams failed the activity. During the jump rope activity, coordination and communication are important. These concepts hindered participants from successful completion of the task. Likewise, in activity 1, lack of communication hindered the participants. When drawing the home, each member…… [Read More]

Sickle Cell Disease Treatments and Education

Sickle Cell Anemia: Ethical Considerations
The only known cure for sickle cell disease is hematopoietic stem cell transplant (HSCT). Survival rates after HSCT are high, almost 100%, with cure rates of more than 90% (Nickel, Hendrickson & Haight, 2014; Nickel & Kamani, 2017). To receive HSCT most successfully, the donor is ideally a HLA-identical sibling. This raises several ethical concerns. The most pressing of all ethical concerns related to HSCT is whether the procedure should be offered to children with “less severe” cases of sickle cell disease (Nickel, Hendrickson & Haight, 2014; Nickel & Kamani, 2017). Less severe cases have been defined as those that do not have overt complications. However, Nickel, Hendrickson & Haight, (2014) point out that many “less severe” cases may become more severe over time, compelling healthcare workers to offer HSCT to all children with sickle cell disease. The same issue of access to HSCT is…… [Read More]

Transition of Patients With Sickle Cell Disease

Sickle Cell Disease

Recent years have seen a number of different investigations of the issues involved in the transition of care -- from pediatric-oriented to adult-oriented services -- for those who suffer from sickle cell disease. Although different researchers have taken a number of different approaches to the question, which I hope to survey in order to provide some report on the current state of opinion regarding transition of care, all are agreed that the current flurry of investigative interest stems ultimately from a piece of very good news: the vertiginous decline in mortality rates for children suffering from sickle cell disease. The historic response to a diagnosis of pediatric sickle cell disease was to minimize patient and parental expectations for prognosis, for the prospect of reaching adulthood would be slight indeed. Telfair Loosier (2004) note that survival rates for pediatric sickle cell disease have improved so vastly that the…… [Read More]

Coping With Sickle Cell Disease

III. Considering Current Challenges

As noted during the introductory chapter of this proposal, children routinely note how their parents cope with pain; their particular pain coping styles. During the implementation of this proposed study, this researcher expects to create a questionnaire... exploring the way parents of adolescents afflicted with SCD personally handled their pain. Both parents and adolescents will be solicited to contribute to the following components will the condensed/adapted to utilize in creating questions for parents of the adolescents with SCD, as well as, for interviewing and/or surveying adolescents with the disease.

Areas adolescents with SCD most need help

Obtaining accurate information about SCD

Considerations for coping with everyday challenges

Getting/giving help

Sharing strength; stories; suggestions with others

Supporting, as well as accepting support

How to best deal with family conflicts

How to cope when one feels he/she cannot

Learning to live, while living and learning

Simple strategies to…… [Read More]

Sickle Gene Therapies for Sickle

Implications for ongoing research into genetic therapies and side effects/later developments are discussed at length.

Yannaki, E. & Stamatoyannopoulos, G. (2010). Hematopoietic stem cell mobilization strategies for gene therapy of beta thalassemia and sickle cell disease. Annals of the New York Academy of Sciences 1202: 59-63.

Though the clinical trial these two researchers are involved in does not yet have results that are ready for publication, the review of the risks they provide regarding the use of stem cell mobilization with G-CSF in patients with sickle cell is highly useful information. So, too, is the practice of pre-treating patients with hydroxyurea before administering the stem cell treatment, which the authors describe in detail and which forms the basis of the related clinical trial. Potential reduction of risks appears to be quite promising, though final results from the clinical trial and other supporting evidence will of course be required.

Ye, L.,…… [Read More]

Political Influence Over Stem Cell

Going back further, the same religious principals also inspired opposition to organ transplants and blood transfusions; before that, the Catholic Church strictly forbade any forensic scientific research, necessitating the need to dissect cadavers for medical education entirely in secret (Levine, 2008).

Just as the news media are partially at fault today for their failure to distinguish legitimate concerns from ludicrous fears in connection with the ongoing political debate over American healthcare, they are equally responsible for allowing unfounded fears of "human cloning" in connection with the beneficial uses of stem cell science. Specifically, the main source of secular opposition to stem cell research is attributable to unnecessary fears of rampant misuse of human cloning technology to clone human beings. While human cloning is hypothetically possible, no responsible scientific researcher would ever misuse current biomedical technology in that fashion. The complexities of cloning entire organisms have been well documented in animal…… [Read More]

Stem Cells Without a Doubt One of

Stem Cells

ithout a doubt, one of the most controversial topics of popular discourse is stem cell research. Indeed, one would be hard pressed to peruse the newspaper or magazine stand without encountering some reference to the global stem cell debate -- but what, exactly, are stem cells, and why are they so controversial?

Stem cells intended for use in human applications are harvested from humans, umbilical cords and embryos. The reason these cells are so valuable is because of their capability to produce or "become" other cell types -- for example, brain cells, heart cells, skin, etc. In short, these are "master cells," holding the ability to divide in cultures, and to be manipulated allowing it to transform into any type of cell. Of course, this is extremely important due to the fact that scientists can use this capability to either create organs (thereby helping to meet the tremendous…… [Read More]

Stem Cell Cience Must Be

Unfortunately, a tremendous amount of valuable research has been put on hold ever since the ban of federal funding for stem cell research. In the United States, the vast majority of medical research of all types that eventually lead to cures for disease are funded by the federal government. The federal ban on stem cell research does not completely prohibit it, but the effect is nearly the same, just as it would be if the federal government withdrew funding for cancer or diabetes research.

The main opposition to stem cell research comes from the Religious Right who believe that any form of research using fetal stem cells is wrong, because according to their religious views, every fertilized human egg should be considered as much a human being as any living person, even a microscopic zygote consisting of nothing more than four cells of human tissue. Certainly, the concept of religious…… [Read More]

Hydroxyurea Segal J B Et Al 2008 Hydroxyurea

Hydroxyurea

Segal, J.B., et al., (2008), Hydroxyurea for the Treatment of Sickle Cell Disease,

Baltimore, MD: AHRQ

Variables/Key Concepts

To determine efficacy, effectiveness, harms, and barriers of the use of hydroxyurea treatment of sickle cell disease for determining solutions and further research need.

Sampling

Research studies based on variables.

Conducted by experts in sickle cell disease management, clinical trial methodology, systematic review, epidemiological studies, and ethics and adherence research.

Instruments/Data Collection

Instruments were quality assessment, data extraction, and evidence grading. Literature inclusion tailored toward research questions. Studies on children and adults evaluated separately. Included randomized trials, non-randomized trials, cohort studies with control groups, and pre/post studies. Evaluations of data was based on variable-based research questions.

Results

Hydroxyurea lowered the rate of hospitizations among children with sickle cell disease and raised HbF cell percentages.

Strengths/Limitations

Limited evidence for toxicity, barriers, and guide dosing. Insufficient evidence for efficacy and safety.

Critique

Even…… [Read More]

Case Study Identification and Rationale of Disease

Alterations of Hematology and Cardiovascular Systems

Sickle Cell Anemia

Ms. A is suffering from Sickle cell anemia. In this disease, the red blood cells appear in the shape of sickles or letter C. The normal red blood cells are disk-shaped. The disk-shape allows them to move smoothly in the blood vessels. Normal red blood cells have hemoglobin. The hemoglobin is responsible the red color. It helps in the transportation of oxygen. Sickle cells, on the other hand, have abnormally low hemoglobin, which results in the C-shape. This form is sticky and stiff and so cannot move easily through the blood vessels. Ms. A's condition was a case of Menorrhagia as well as dysmenorrhea. The sickle cells lump together and block the flow of blood through the blood vessels leading to the organs and the limbs. Such blocked blood vessels may lead to pain, infections and even organ damage (Health 24,…… [Read More]

Educational Brochure or Handout on Chronic Venous Insufficiency

Pathophysiology

What's Gone Wrong?

CVI is generally an indication of blood stasis or venous reflux, most commonly valvular incompetence in the low-pressure superficial venous system. The inability of blood to return to the heart from the legs causes it to pool and clot. CVI generally occurs within the deep veins (Deep Vein Thrombosis), may also be related to varicose twisting, valve malformations or pelvic tumors.

isk Factors

Obesity, inactivity, pregnancy, smoking and extended periods of standing or sitting tend to be the activity factors of most importance. Women often present varicose veins; men DVT but this may be associated with delayed reporting. Type II Diabetes may also suggest different gender propensities. People over 50 predominately display indicators.

Etiology

CVI results from damage caused to the veins, though clotting itself can precipitate vascular dilation. Varicose veins are often hereditary as may be valve defections which can result in venous reflux. Other…… [Read More]

Student Degree Health Adminstration I Worked a

student, degree Health Adminstration. I worked a health care staffing supervisor 10 years. personal experience incorporated paper fact husband sickle cell anemia I cared 20 years.

I have always been drawn to helping people, both in my life and in my career pursuits. In planning the next phase of my life, I wanted to follow a path which would allow me to better the lives of others while also learning new things every day. I have come to realize that nursing is the profession that suits me best because of my interests, my experience, and my goals.

A degree in nursing would be the second degree that I have pursued. My first degree was in Health Administration. I chose to study that field because I knew that I wanted to work in a health care setting, where my actions would be at least indirectly responsible for aiding in the well-being…… [Read More]

How a'specific'situation impacted your academic performance

I am writing this appeal with the main purpose of explaining the circumstances that influenced my academic performance. At the outset, please consider the trying conditions under which I completed the academic work, rather than as an excuse for the dismal grades.

I had a very challenging time in the preceding semester, and as a result, my grades suffered. My mother, a sickle cell patient became very ill in the middle of the first semester, which sadly led to her demise. Whilst my mother was ill, I found it very difficult to find ample time to work. I was forced to take breaks and head home during the weekend, and during school days to make certain that my siblings were taken care of in terms of meals and clean clothing. I had to attend home routines and domestic tasks. These forced undertakings left me with little time for studying and…… [Read More]

Hemolytic Disease of the Newborn

History of Pediatric Hemolytic Monitoring

Retrospect to the career of physician, Dr. James A. olff I and his early progress in treatment of Rh hemolytic disease as described in Pochedly (1984), looks at the development of interest in hematology in European field hospitals during orld ar II. After the war period, the transformation of olff's research in this area was advanced by research conducted during a pediatric residency at the Boston Children's Hospital, between 1945 and 1947. During his tenure at Children's he was engaged with Dr. Louis Diamond in his seminal investigation on treatment of erythroblastosis fetalis by exchange transfusion.

Collaborative efforts with Drs. Diamond and Farber focused on preliminary clinical trials of aminopterin for the treatment of acute leukemia, of which olff was in observation. Instrumental to the development of the concept of treating erythroblastosis fetalis by exchange transfusion; collaborative in the area of pathophysiology of disease where…… [Read More]

Genomic Medicine

Human Genome Project

Launched in 1990 as a collaborative initiative between the National Institutes of Health and the U.S. Department of Energy, the Human Genome Project completed its goal ahead of time despite the enormous challenges that were involved (Greene, 2006). The goals of the Human Genome Project included developing comprehensive genetic and physical maps of the human genome in order to determine the complete nucleotide sequence of the three billion base pairs that make up the human DNA and to identify the estimated 100,000 genes that are contained within the human genome (Greene, 2006). To determine the importance and implications of the HGP, this paper reviews the relevant literature, followed by a summary of the research and salient findings concerning this initiative in the conclusion.

eview and Discussion

1)

How will research in the Human Genome Project further medical research? What disorders are most likely to benefit from the…… [Read More]

Maternity Nursing Labor and Delivery and Newborn

Maternity Nursing, Labor & Delivery / Newborn

Labor and Delivery Terms

Para: Para refers to the number of live births a woman has had (it might be a stillbirth, or twins, or even triplets) past the 20-week gestation period (Zimmerman, p. 116).

Gravida: this refers to the number of times a woman has been pregnant, whether she actually gave birth, had an abortion or a stillbirth (Zimmerman, p. 116).

Amniotic Sac: this is a membrane around which the fetus is surrounded. It is a strong series of membranes that is visible after 7 weeks of gestation. (Jurkovic, et al., 2011).

Cervical Effacement: this phrase refers to the measurement of the expansion of the cervix as the baby gets closer to being born. hen the cervix is 50% effaced, it is halfway to being ready for the baby to be born (Jurkovic, et al., 2011).

Cervical dilation: Slowly but surely the…… [Read More]

Strokes and African Americans

Strokes and African-Americans

African-Americans are reported to be nearly twice as likely to experience a stroke as their white counterparts however, African-Americans are much less likely to know the risk-factors and symptoms of stroke or to seek early treatment. The purpose of this study is to examine the issue of African-Americans and stroke. The significance of this study is the additional knowledge that will be added to the already existing base of knowledge in this area of study. The methodology employed in this study is of a qualitative and interpretive nature and has been conducted through a review of literature in this area of study.

Strokes and African-Americans

African-Americans are reported to be nearly twice as likely to experience a stroke as their white counterparts however, African-Americans are much less likely to know the risk-factors and symptoms of stroke or to seek early treatment.

Purpose of the Study

The purpose…… [Read More]

Cultural Differences That Surface When

These, then, eventually die leaving the transfer of oxygen in your blood being absolutely limited and far below the point at which the flow of oxygen needs to be in a human body. The flow of blood and transfer of oxygen eventually slows down tremendously and can cause terrible pain as well as make the immune system to be vulnerable to a variety of different diseases. There are many medical procedures that can allow the individual to find a relief (Lozoff et al., 2003).

In our case study, we will mainly highlight how the mother's approach was tentative and skeptical and how the four points that have been mentioned initially (communication, social organization, spatial dynamics and locus of control) are impacted through her approach. The first important thing to note about the attitude of the mother is that she does seem very forthcoming to find out as much as she…… [Read More]

Genetic Screening

Genetic screening is one of the most controversial topics in the scientific arena today. The advent of the Human Genome Project, which maps the complete human genetic code, has brought this issue to the forefront. This paper will discuss the basic science that underlies genetic screening, applications of genetic screening, and investigate some of the common misconceptions and ethical questions about its use.

Genetic screening itself is simply "the systematic search within a population for persons possessing particular genotypes, which are either associated with disease, predisposing to disease, or leading to disease in descendants" (Miller). In simpler terms, genetic screening involves testing and determining whether "an individual's genetic material to predict present or future disability or disease either for oneself or one's offspring" (McCarrick). Essentially, genetic screening is conducted for several basic reasons, including the care of the ill and the prevention of disease, providing reproductive information, determining the incidence…… [Read More]

Race Genetics

ace and Genetics

On the surface, race seems like a legitimate way of categorizing human beings. Physical characteristics are passed down from parent to child, thereby recreating racial markers. However, the concept of race is generally rooted in ignorance. ace is an ephemeral construction, and genetic science is proving this to be so. If race were real, then there would be ways of tracing different races back to a few ancestors: such as an ancestral Polynesian, ancestral African, and ancestral Jew. As it stands, though, all human beings trace ancestry to the same basic gene pool from humanoid ancestors in Africa. This one fact alone is sufficient to debunk the concept that race "exists," or is a form of biological determinism. There are other reasons to believe that race is not as real as was once thought. ace is not real, and the reasons are rooted in genetic science, anthropology,…… [Read More]

Premarital Screening Program in Saudi Arabia

Edit Research Premarital Screening

Evaluating Premarital Screening Knowledge in Saudi Students

The purpose of this research was to investigate the impact of premarital screening (PMS) in Saudi Arabia. The use of PMS as a means to identify and approach both and infectious and hereditary disease was investigated in order to determine the impact of this practical approach.

A cross-sectional study was conducted at Jazan University from January to June 2014 to perform this research. A self-administered questionnaire was distributed to 1000 Jazan University Students, both males and females. The questionnaire consisted of 3 main parts. The first part was based on socio-demographic data, the second part dealt with the students' knowledge about the premarital screening program while the third part explored their attitudes towards the screening program.

Results

The vast majority of the participants (922; 94%) believed that a PMS program was a preventive measure. More than two thirds of…… [Read More]

Cholecystitis Biliary Colic and Cholecystitis Are in

Cholecystitis

Biliary colic and cholecystitis are in the spectrum of gallbladder disease, ranging from asymptomatic gallstones to biliary colic, cholecystitis, choledocholithiasis, and cholangitis (Santen pp). hen gallstones temporarily obstruct the cystic duct or pass through into the common bile duct, gallstones become symptomatic and biliary colic develops, however, if the cystic duct or common bile duct becomes obstructed for hours or gallstones irritate the gallbladder, then cholecystitis develops, and when the stones become lodged in the common bile duct, choledocholithiasis occurs, resulting in possible cholangitis and ascending infections (Santen pp).

Cholecystitis is an inflammation of the gallbladder caused by obstruction, usually a gallstone, of the cystic duct, and the inflammation may be sterile or bacterial and the obstruction may be acalculous or caused by sludge (Santen pp). Bacterial infection is believed to be a consequence, not a cause, of cholecystitis, approximately 75% of bile cultures are positive, with the most…… [Read More]

Business Law Discuss the Doctrine

A company cannot refuse to hire someone with sickle cell anemia (a disease that primarily affects persons of African ancestry), because the person might require costly health insurance, for so long as the person was strong enough to perform the job, discrimination would not be acceptable as it would affect persons disproportionately of one racial category.

Question

Explain trade secret and how it could be protected legally and in day-to-day operations. Provide an example.

According to Nolo.com, an online legal dictionary, a trade secret is:

in] most states, a formula, pattern, physical device, idea, process, compilation of information or other information that 1) provides a business with a competitive advantage, and 2) is treated in a way that can reasonably be expected to prevent the public or competitors from learning about it, absent improper acquisition or theft" ("trade secret, 2007, Nolo.com). Perhaps the most famous trade secret in business is…… [Read More]

Hemophilia the Most Common Genetic

The viruses that cause AIDS (HIV) and hepatitis can be carried in clotting factors however there have been no documented cases of such transmission in about ten years. Prevention of viruses can be prevented by: careful screening of donors; testing of donated blood products; treating donated blood products with a detergent and heat to destroy viruses (Hemophilia 2006). Both preventive and as-needed therapy can be administered at home, thus resulting in quicker treatment, fewer doctor or emergency room visits, and less costs. Vein access devices can be surgically implanted to allow easier access to a vein however infections can result from such devices (Hemophilia 2006).

All patients with bleeding disorders may benefit at times from using aminocaproic acid, an oral antifibrinolytic medication that helps stabilize clots (Curry 2004). Aminocaproic acid is the only product available in the United States in oral form, however it is not user-friendly, with dosing every…… [Read More]

Marketing Case Study Explain What You Think

Marketing Case Study

Explain what you think would be an appropriate promotions strategy for both of them. In doing so compare and contrast the two promotions strategies explaining why you think they would be similar or different.

NINE POSSIBLE PODUCT -- MAKET COMBINATIONS

POSSIBLE TAGET MAKETS

GAY MEN O WOMEN

BLACK WOMEN AGED 18-30

HANDGUN OWNES

PODUCT CATEGOIES

VACATIONS

NON-LETHAL PESONAL SECUITY PODUCTS

FITNESS / EXECISE PODUCTS

More than one billion adults worldwide are overweight. In the United States alone obesity is responsible for an estimated 300,000 deaths annually. What's interesting is that nearly all of these deaths are preventable through proper exercise and nutrition. As such, fitness is a very contentious issue plaguing many of the developed nations worldwide. Statistics indicate that nearly 33% of all Americas are obese. This bodes very well in regards to marketing as 1 in 3 Americans could use the fitness and exercise related…… [Read More]

Healthcare Leadership & Prejudices Healthcare

Conclusion

Prejudice and ethical/leadership issues with healthcare are nothing new but the fight to keep those standards and ethics on an even keel and prevent racism, bigotry and predudice of any sort including based on class, money, political ideology, nationalism, and so forth should be stomped out and eviscerated whenever it can be. People are people and should treated with dignity and respect regardless of their race, gender, beliefs and so forth. Even convicted murderers and rapists should not be treated disdain due to their actions because doing otherwise lowers the ethics and standards of the healthcare community that can and should still apply at all times.

eferences

Callahan, M. (2008). Healthcare providers constricted by financial, legislative, and regulatory issues. The Journal of Medical Practice Management: MPM, 24(3),

143-146.

Cobaugh, D., Angner, E., Kiefe, C., ay, M., Lacivita, C., Weissman, N., & ... Allison, J.

(2008). Effect of racial differences…… [Read More]

CPOE Themed Annotated Bibliography

Charles, K., Coustasse, A., & Willis, K. (2014). Does CPOE Increase Patient Safety by Reducing Medical Errors? Global Education Journal, 2014(1), 1-14.

The purpose of the research project was to determine if adoption of a CPOE system would be an effective elucidation to the problem of medical errors as well as determine what caused the medical errors.

The results pointed to reduction in adverse drug events and medical errors significantly using CPOE and demonstrate through review that CPOE provides a higher accuracy through ease of electronic use of data.

Evidence: By using information taken from previous research articles and studies, the authors determined CPOE can minimize medical errors and can be beneficial especially due to the financial incentives brought on by the HITECH Act of 2009.

Relation: This source supports other sources and evidence because it shows how beneficial CPOE is to patient care through reduction of medical errors.

Currency:…… [Read More]

Ethics of Human Cloning in 1971 Nobel

Ethics of Human Cloning

In 1971, Nobel Prize winning-scientist James atson wrote an article warning about the growing possibility of a "clonal man." Because of both the moral and social dangers cloning posed to humankind, atson called for a worldwide ban on any research leading to cloning technology (atson 8).

Until then, cloning had been largely relegated to the realm of science fiction. Scientific research concerning cloning and in vitro fertilization was obtuse and technical, and hardly written about in the news. atson, however, was a highly-respected scientist, a Harvard professor famous for his discovery of the double helix structure of the DNA. The article he wrote sparked an intense debate over cloning, a debate that was renewed with the 1996 birth of Dolly the lamb, the first cloned mammal.

The argument no longer centers on whether cloning is possible, but on whether cloning is ethical. This paper examines the…… [Read More]

Sexual Enhancement Viagra Levitra and

(American Society of Health-System Pharmacists, Inc. 2009 )

IV. Side Effects of Sildenafil

Side effects of taking Sildenafil include those as follows:

headache heartburn diarrhea flushing (feeling of warmth)

nosebleeds difficulty falling asleep or staying asleep numbness, burning, or tingling in the arms, hands, feet, or legs muscle aches changes in color vision (seeing a blue tinge on objects or having difficulty telling the difference between blue and green)

sensitivity to light (American Society of Health-System Pharmacists, Inc. 2009 )

Serious side effects are the following and occurrence of this requires immediate notification of the physician:

sudden severe loss of vision (see below for more information)

blurred vision sudden decrease or loss of hearing ringing in ears

erection that is painful or lasts longer than 4 hours dizziness or lightheadedness fainting chest pain worsening shortness of breath itching or burning during urination rash (American Society of Health-System Pharmacists, Inc. 2009…… [Read More]

Improving the Quality of Medical

This is particularly the case in sub-Saharan Africa where clinicians have often come to rely on signs and symptoms alone to make diagnoses." (Nicoll, Walraven, Kigadye, Klokke, 1995)

The laboratory environment is critical to administering testing to determine population rates of HIV / AIDS throughout nations and perhaps continents where the lacking of resources facilitates a substandard environment for care. In the case of the African nation of Mozambique, which perhaps can be understood as a case indicative of the environmental assessment one would find throughout Africa and therefore, can be labelled to be a median statistical nation. A nation representing the median would indicate that half of the population nations that are categorized as resourced deficient, half would be above Mozambique in terms of resource allocation and half would fall below.

esearch into the quality of HIV / AIDS case-detection and case-reporting system in Mozambique was conducted by (Chilundo,…… [Read More]

Speech on the Benefits of

Since the war in Iraq, thousands of American soldiers have been injured, and some of them paralyzed by explosions that shattered their spinal columns.

Traumatic paralysis is often irreversible because the network of nerves in the human spinal cord cannot repair themselves when they are badly damaged.

Applications of cloning technology will allow us to grow new nerve tissue for implantation into damaged spinal cords to restore their functions (Sagan, 1997).

Seventh Point - Cloned Human Organs Can Save Thousands of Lives Every Year:

Medical applications of cloning technology already allows doctors to grow human skin for burn victims.

The exact same technology will allow us to make human organs by actually cloning the cells from the same person to make replacement organs (Soares, 2002).

This means an end to long waiting lists for donor organs and will make the difference between life and death for thousands of people every…… [Read More]

Phenotype How Variations Arise Within a Phenotype

Phenotype

How variations arise within a phenotype?

Phenotype is the specific characteristics that are displayed by the organism. Phenotypic variation is a prerequisite for evolution due to natural selection, thus without the former, there is no latter. Qualitative traits are traits that show a difference between phenotypes like skin color, sex, and eye color. However, such descriptions are controlled by a small number of genes so environmental influence on these traits is low since it involves the genetics of individuals. Quantitative traits are traits that exhibit a continuous range from one phenotype to another. Therefore, there is no difference between phenotypes and are usually influenced by several gene pairs while the environment has a significant influence on the trait. This type of trait involves the genetics of populations. It is a combination of genetic and environmental factors to produce phenotypes that blend into each other. Phenotypic variance or VP is…… [Read More]

Africans Had Poor Health Care in the

Africans had poor health care in the 1950s

There is much that still remains swept under the proverbial carpet about America's treatment to its African immigrants. One of the chapters, little known and often left untold has only recently started to emerge and concerns American health care system and its using Blacks as guinea pigs.

Attorney and author Vernellia . Tandall tells the story in her book 'Dying While Black' showing how America's health care system was built on the bodies of African-American individuals from the 19th century continuing to present days. Some f the information is unbelievable at best shocking at worst such as her allegations that AIDS was created by a government-sanctioned health care for the purposes of medical advancement.

Countless stories from Black residents of both North and South tell about how they were unwillingly and unknowingly abducted and exploited for medical experiments. There were the 'night…… [Read More]

Physical Life Science Genes Are

During the gene decoding process the double stranded DNA splits up to reveal a single strand from which the base sequence of the gene is copied onto a single stranded nucleic acid known as the messenger ribonucleic acid or mRNA. This implies that we have an exact copy of the gene base in the mRNA except that Urasil (U) replaces the T. base and deoxyribose is replaced by ribose. Translation on the other hand is the actual process of protein synthesis from the mRNA strands. Ribosomes work with the mRNA for protein synthesis within the cells. [the State University of New York]

4) Mutation, Gene Migration, Genetic Drift, Non-random Mating and Natural Selection are the five processes that can affect the frequency of genes in a population. [CMGS]

5) Kindom Protista is considered to be the ancestor of all eukaryotic kingdoms and includes algae, plant like, animal like and fungus…… [Read More]

Dangers Outweigh Benefits of Genetic

Researchers at Cornell University discovered that Monarch butterfly caterpillars died when they ate plants dusted with the pollen of Bt corn that was growing in nearby fields, and many scientists worry that with so much insecticide in the corn plants, insects might develop a resistance to it (Dyer 2002). These fears and concerns are echoed by Francis Fukuyama who believes that genetic enhancement will undermine the system of human rights by disrupting the boundary that encloses all humans in a single group, thus believes society should limit genetic science to allow therapy but prohibit enhancement, such as genetically altered food crops, and non-therapeutic procedures (Tobey 2003). In other words, enhancement will allow society to increase genotypic and phenotypic diversity, yet such diversity will press society to the point of losing its shared humanity (Tobey 2003).

orks Cited

Adams, endy a. (2002, January 01). Reconciling private benefit and public risk in…… [Read More]

Management of Osteomyelitis in the Diabetic Patient

Osteomyelitis in the Diabetic Patient

Management OF OSTEOMYELITIS IN THE DIABETIC PATIENT

Osteomyelitis is an infection of the bone or bone marrow which is typically categorized as acute, subacute or chronic.1 It is characteristically defined according to the basis of the causative organism (pyogenic bacteria or mycobacteria) and the route, duration and physical location of the infection site.2 Infection modes usually take one of three forms: direct bone contamination from an open fracture, puncture wound, bone surgery, total joint replacement, or traumatic injury; extension of a soft tissue infection such as a vascular ulcer; or hematogenous (blood borne) spread from other infected areas of the body such as the tonsils, teeth or the upper respiratory system.2(p807) Bacteria such as Staphylococcus aureus, Pseudomonas, Klebsiella, Salmonella, and Escherichia coli are the most common causative agents of the disease, although viruses, parasites and fungi may also lead to the development of osteomyelitis.3

Patients…… [Read More]

Characteristics of Pain

Perception of Pain

Uses of Pain in nursing

Definitions of Pain from Dictionaries

Uses of Pain in psychology

Defining attributes

Model case

elated Case

Contrary Case

Antecedents and Consequences

CONCEPT ANALYSIS OF PECEPTION OF PAIN

The aim of this paper is to increase the understanding of the perception of pain. The researcher purpose to clarify describe the characteristics of pain and recognize antecedents that effect the idea of pain and the likely outcomes of pain by utilizing Avant's and Walker (2005) theory of study. Also, a model case shows how pain is connected to these serious characteristics contrary case and a borderline case are shown to distinguish the perception of pain from other notions. Empirical referents show the current point-of-view of the perception of pain. (Akyol & Salmond, 2009)

Concept Analysis of Characteristics of Pain

Introduction

The goal of this paper is to expand the understanding of the concept of…… [Read More]

Genetic Counseling

Genetic counseling involves the sharing vital information and knowledge by experienced and well trained experts in the field of genetics for individuals with high risks of suffering some genetic disorders or transferring it to their children. It is the responsibility of a genetic counselor to provide relevant information concerning the hereditary nature of certain diseases and their risks of reoccurrence; addresses the concerns of patients, their health care providers and their families; and lends assistance to both the patients suffering these hereditary ailments and their families.

The first genetic counseling center was the Hereditary Clinic established at the University of Michigan in the United States in 1940. Since then, several such centers have been established in different parts of the world.

Through genetic counseling, information is made available to give the needed support to people who are dealing with any genetic disorder or at risk of developing one. When dealing…… [Read More]

Important Factors in Treating Huntington's Disease Patients

Huntington's disease (HD) was the first autonomic dominant disorder for which genetic prediction became possible" (Harper, et al., 2000, Journal of Medical Genetics, p. 567). HD is a disease that occurs due to an inherited disorder leading to the death of brain cells. A diagnosis of HD is accomplished through genetic testing which can be implemented at any age regardless of whether the symptoms manifest or not. Although, the specific symptoms vary between people, nevertheless, symptoms can start with people between 35 and 45 years of age and can also start in some individuals at even anearlier age. The disease may affect successive generations if health interventions are not implemented (Mandel, 2016).

Additionally, "the cause of HD is due to a dominant mutation of autosomal form of the gene called Huntington. This shows that a child born by an affected person has a 50% chance of developing or inheriting the…… [Read More]

H1N1 Virus

H1N1

I chose this topic because the H1N1 virus and the swine flu have taken over the news. The Ohio Department of Health is heavily committed in getting the word out. "During the week of October 18-24, 2009, influenza activity continued to increase in the United States as reported in FluView. Flu activity is now widespread in 48 states. Nationally, visits to doctors for influenza-like-illness continue to increase steeply and are now higher than what is seen at the peak of many regular flu seasons. In addition, flu-related hospitalizations and deaths continue to go up nation-wide and are above what is expected for this time of year." (ODH).

The story is both a local and national headline. The television news report '60 Minutes' lead off this week's show with a serious discussion about all aspects of the new viral spread of the H1N1 virus and issues regarding the production process…… [Read More]

Spirit Catches You the World

They cannot ignore the socioeconomic issues of adversity so often present and, where necessary, need to act as advocates, mediators and social brokers (Compton, Galaway, & Curnoyer, 2005).

The concern is that the issue of healthcare for culturally diverse individuals is so complex, there are no exact rights and wrongs. For example, in Fadiman's book, no person(s) can be said to be ultimately correct or incorrect in his/her behavior or actions; everyone did what he/she thought was right. In order to help others who have different cultural backgrounds and experiences, as the Hmong, it is essential to be 1) proactive. That is, to forecast the transforming demographics in the U.S. over the coming decades and put plans into place that will best serve these individuals and 2) collaborative. The best results occur when professionals from different backgrounds and expertise share best practices and learn from each other. What could have…… [Read More]

Ethics and Professional Responsibility in

However, this form of racism rejects racial rights and instead calls for active racial competition among races towards achieving mastery and territorial dominance. This is a form of racial survival for the fittest in which there is no belief of the existence of racial rights (McCulloch 2010, p. 1).

Despite the negative connotation of racism, there is a need to have some form of racism, but in a positive manner. Arguably some form of racism is necessary. For example, there is a need to socially map and define the racial landscape and this cannot be done without the use of some form of racism. This has indeed been a historically compelled action because throughout history, racial lines have naturally existed between men and thus could not be ignored (Pataki & Levine 2004, p. 87-90). Therefore, it can be conclusively stated that the society cannot cast a blind eye to racism;…… [Read More]

Illusion of Race Race Power

Nowhere on earth is a thirteen-pound, six-foot long unit of 'scandal' or 'integrity' to be found, for example. Nor apparently can someone find a benchmark unit of 'race'.

The second thread runs through the slides 1887, 1934 and 1997. Jim Crow led to better homes for whites than Blacks even after they fought WWII side by side. What this demonstrates is one clear way we very literally live within the tangible outcome of discrimination today, and the Web site goes on to expand on this in "Where Race Lives" and "To See or Not To See" very convincingly. What interests me here is specifically the assertion that "Jim Crow unites poor and wealthy whites, while denying African-Americans equality." I do not contest that the U.S. legal, i.e. white, institution actively and deliberately removed non-whites' means to confront and dismantle discrimination at law. Nor do I contest that the intent of…… [Read More]

Heritage Assessment Tool Cardsmax Upon Completing the

Heritage Assessment Tool

Cardsmax

Upon completing the Heritage assessment tool there were several things that I realized. The primary realization was that in my family we do tend to cling to those things familiar, we seek things that are known and comforting. Some of the common health issues in my family consist of Cancer, Diabetes, and cardiovascular disease. In my family, these are issues that have not only been handed down within my bloodline, but they have been issues within my heritage for as long as you can trace back.

When looking at health maintenance there are certain things that have occurred in my family for generations to try to hinder the onset of certain illnesses and disorders, physical activity and a healthy diet have been important because if the increased risks of cardiovascular issues as well as the high chances of having high blood pressure and diabetes (Last-Name, 2011).…… [Read More]

Colonial Latin America

Born to Die

hy did the native populations, such as the Incas and the Aztecs, appear to be, not equals to be met with military and diplomatic force, but as victims born to die in the eyes of the invading European powers? hy were they not feared, despite the extensive technological capacities of their civilizations, and the detailed political and religious theology these civilizations created? Simply put, the invading Europeans came to regard them as sick and ailing bodies of a sick and ailing body politic, born to die because of their lack of immunity to European diseases, even more than European firearms.

The book Born to Die thus presents the provoking thesis that disease was the major cause of the European power's seemingly never-ending successes of colonial successes and conquests in Latin America, rather than these nation's prowess in military conquest. In some cases, the nations had already been…… [Read More]

Guns Germs and Steel The

Till the period up to 11,000 BC every individuals remained Stone Age hunters/gatherers. Nearly that time, the roads of growth of human societies on various continents started to move away in a large scale. (Guns, Germs, and Steel- the Fates of Human Societies: (www.2think.org) During that period, when Stone Age hunter-gatherers comprised the total human population, a big segregation happened in the proportion that the human societies progressed. In Eurasia, several regions of Americas, and Africa, agriculture started to be the existing pattern of livelihood when domestication of aboriginal wild plants and animals were done by the prehistoric planters and herders. Diamond fairly examines the human history on each continent starting from the Ice Age at a proportion that stresses just the widest traversals of people and concepts. However, his assessment is symmetrical: one eye has rather long-term view of the evolutionary biologist, whereas the other eye and his spirit…… [Read More]

Rheumatic Fever

heumatic Fever

The Etiology, Incidence and Treatment of heumatic Fever Today

Like many diseases such as smallpox and polio, Zamula (1987) reports that until fairly recently, rheumatic fever was described by most public health officials as being a vanishing disease. "After World War II," Patlak (1991) reports, "the number of cases of rheumatic fever dramatically declined until, during the 20 years between 1965 and 1985 alone, the yearly number of cases of rheumatic fever among school-age children dropped by more than 90%" (p. 24). At the time, clinicians assumed that less crowded living conditions and the use of antibiotics were controlling the disease and some physicians called rheumatic fever a "vanishing disease in suburbia" (Patlak, p. 24). As a result, the children's hospitals that were previously dedicated to the care of rheumatic fever sufferers closed because of a lack of patients and disease registries that had been rigorously maintained by…… [Read More]

Jazz Biography

Miles Davis

One cannot think of Jazz without thinking of Miles Davis. Davis is widely regarded as one of the foremost jazz trumpeters. However, it would be a mistake to believe that Davis' influence on the world of jazz was limited to his abilities as a trumpeter. Davis was recognized as a composer, a bandleader, and a keyboard player. In addition, Davis helped develop improvisational playing techniques, which incorporated modes. Finally, "Davis had an uncanny ability of always selecting great sidemen for his recording sessions. These recordings are full of original and creative sensitivity and are outstanding examples of jazz recordings made at that time." (The Official Miles Davis Website, 2001).

If Davis' mother had her way, jazz music today would be dramatically different. Davis was born to Miles Henry Davis, a dentist, and Cleota Davis. Cleota Davis was a blues pianist, but she kept that fact hidden from her…… [Read More]

Anthropology and Race Concept it

It would be easy to assume, then, that biologists are making a mistake by rejecting the race concept because that rejection would force them to also ignore such biological variation. However, this assumption would be false. Most intelligent anthropologists are not rejecting the idea of biological variation or a geographical/genetic component to that variation. On the contrary, they reject the idea of "race" specifically because it is not flexible enough to accurately model the full range of biological variation and therefore lumps all geographic/genetic variable populations together based on a small subset of their traits.

The race concept would lump together, for example, both the small and slightly darker Mediterranean body build with the robust, blond Nordic body build as both "White" while assuming that all the wide variety of genetic, facial, and morphological differences in Africa rendered a single "Black" race. The critical anthropologists would have to reject such…… [Read More]

Science in Spite of Its

Geneticists have been trying to unearth so-called founder mutations: one original genetic mutation that subsequently caused generations of people to carry and/or suffer from a serious illness like sickle cell anemia. Unlike many other mutations, founder mutations can be traced to one original ancestor. The discovery and study of founder mutations allows anthropologists to research the general patterns of human migration, providing a more complete understanding of history. Religion views genetic mutations in a different light. Many fundamentalist Christians, for example, might propose that disease is God-given. Yet if Mary Schweizer, an Evangelical Christian scientist, can unite religion with science then anyone can. Her devotion to fundamental Christian thought is not at odds with her scientific endeavors, according to Yeoman. In fact, Schweizer views science as a spiritual endeavor, as a means to discover the meaning of life, death, and seeming anomalies. Religion and science share common goals and objectives…… [Read More]

Cobra Health Insurance Health Insurance How Cobra

OBRA Health Insurance

Health Insurance

How OBRA Works

Davis was terminated from his employment because of long absence from work and not because he voluntarily resigned or any gross negligence on his part. Therefore, he and his family are eligible for health insurance coverage under the onsolidated Omnibus Budget Reconciliation Act (OBRA) provided his company maintains its group health plan and still has 20 or more employees for which they currently have 100. If his former employer were to have fewer than 20 employees, then he might still be eligible for what is called mini-OBRA. The OBRA Act was put into law in 1986 in order to provide continuation of group health coverage for workers who have lost their jobs. The Act allows for the unemployed individual to avoid any gaps in coverage that would prevent them from having pre-existing conditions excluded once they were able to obtain group health…… [Read More]

Philosophy of Happiness Are There

eligion has the ability to give people hope especially the hopeless. Despite the harsh situations and challenges that people face, religion plays a fundamental role of giving them hope and optimism from which they draw strength. eligion is also an agent for socialization. It is no doubt meeting with other believers for religious events is more than just practicing faith (eeve 2006).

People use the opportunity to meet old friends and make new ones, sing together and above all socialize. Interactions can be a powerful source of happiness to individuals. eligion provides more than just individual hedonism to guide behavior. In essence, religion provides guidelines for faithful to follow and in the end live an orderly and moral life (Furness & Gilligan 2010). Even though people appear to be happier within the spheres of religion, many researchers show that people in relatively nonreligious nation are the happiest lot. Scandinavian societies…… [Read More]

Racial Categories

Fiction of ace

ace

ace: The cultural power of the fiction of race

A recent PBS documentary was titled ace: The power of an illusion. This underlines what constitutes race -- race is a fiction, created by the faulty observational perceptions of human beings, and the history of human culture. ace is not a scientific reality. Because we can see color (and hair texture, facial shapes, and other characteristics) we perceive something we call race. But our scientific knowledge tells us that race does not exist. This is not to deny that race is a very powerful fiction that has influenced human history. The idea of racial categories proved to be deadly and destructive to the lives and the cultures of indigenous peoples. It was used to validate slavery, genocide, colonialism, and exploitation. But race is not 'real,' any more than the idea of 'carrying the white man's burden' was…… [Read More]

Selective Mutism

Mutism

Parents not with great joy as their children meet important developmental milestones. oth first steps and first words are celebrated and described in detail to friends and family. ut sometimes as a child gets older, changes occur. Inexplicably, sometimes children who have talked for several years suddenly stop talking. Typically the child becomes selectively silent, talking animatedly with family and known friends but becoming mute at school or with strangers. When the problem is severe and exists over a period of time, the child may be diagnosed with selective mutism.

In one example, a child who was almost five years old started preschool, and after two weeks, refused to speak either to the teacher or his classmates. He also cried at arrival and would ask his parents to take him home. At home he spoke, but only to his mother, but clearly and in complete sentences. He communicated only…… [Read More]

State Involvement in Healthcare

History Of State Involvement in the Delivery of Health Care

Eugenics

Eugenics is the belief and practice that involves the improvement of genetic quality of the human population.it is a science that deals with influences that are able to bring an improvement in inborn qualities of race also with those that develop them to their utmost advantage. There is a considerable difference between goodness in various qualities and in the entire character as a whole. The character largely depends on the proportion that exists between these quantities whose balance can be greatly influenced by education. This is a social philosophy that advocates for the improvement of the human genetic traits by promoting higher reproduction of people that posses' desired traits also termed as positive eugenics and reducing the reproduction of people that posse's undesired ort less desired traits which is negative eugenics. Therefore Eugenics is a social movement that is…… [Read More]