Stem Cell Essays (Examples)

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Cells Are a Type of

Words: 760 Length: 2 Pages Document Type: Essay Paper #: 54959512



To date, adoptive T-cell therapy have used peripheral blood, tumors, malignant effusions, and drained lymph nodes as sites for injecting the T-cells for adoptive transfer. Those are routinely used are allogenic bone marrow transplantation and peripheral blood stem cell infusion. It is possible that the bone marrow might be a good place too. It is also arguable which precise T-cells are the best to transfer, since T- cells are differentiated into many subsets.

Furthermore, in order to produce enough effectors T-cells, specific T-cells from peripheral blood or tumor specimens are isolated and generated in vitro, and these are then clonally expanded using various approaches. The T-cells are then reinfused into the patient with the expectation that they will then target antigens. There is much evidence that this approach works, although it also seems that this can be engineered in vivo under certain situations.

For most effective T-cell therapy, it has…… [Read More]

Sources

Greenberg, P.D. 1991, 'Adoptive T cell therapy of tumors. Ad. Immunol. 49, pp. 281-355.

Jamieson, B.D., & Ahmed, R. 1989,'T cell memory. J. Exp. Med. 169, pp. 1993-2005

June, C.H. 2007, 'Principles of adoptive T cell cancer therapy', J. Clin. Invest., 117, pp.11204-1212.

MedecineNet.com. Definition of T cell. Online. Available at: http://www.medterms.com/script/main/art.asp?articlekey=11300
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Stem Research and the Anti-Discrimination Position Statement

Words: 518 Length: 2 Pages Document Type: Essay Paper #: 84820583

legislation introduced topic stem cell research. You find Library Congress website helpful research thomas.loc.gov. Pick a piece legislation interest give a summary bill.

The H.R.2433 -- 113th Congress (2013-2014) emphasizes the need for the U.S. To play a more significant role in achieving technological advancements in STEM-cell research. The act was introduced in June 19, 2013. The legislation relates to the idea of changing the Public Health Service Act with the purpose of introducing research processes that make use of human stem cells. The legislation is particularly interesting because of its studies in the field of stem cells involving human embryos.

Although the legislation bring forward problematic ideas because of the difficulty associated with actually coming in possession of human embryonic stem cells, the fact that there are numerous individuals willing to donate such resources with the purpose of promoting scientific advancement makes it possible for experts to progress in…… [Read More]

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Complexity of Cell Division

Words: 1475 Length: 4 Pages Document Type: Essay Paper #: 12632910

Cell Division

All living things are complex organisms that are made up of cells. Some are made up of a single cell while others comprise of numerous cells working together. Cells are the basic functional and structural units of living organisms and are known to be the building blocks of life. In humans it is from a group of cells that tissues are made and from tissues that organs are made which enable beings to live.

Cells obtain food and oxygen through their membranes and each membrane has a specific area which can serve contents of only a given volume. Any increase in volume of the cell requires that the area of the membrane increases. Basically, when cells grow the membrane becomes insufficient in aiding the movement of substances in and out and thus to maintain a favourable surface area to volume ratio, cell division must take place. Furthermore, cell…… [Read More]

References

Bolsover, S., E. Shephard, H. White, and J. Hyams. Cell Biology: A Short Course. 3. Wiley-

Blackwell, 2011. 432.

Conger, Krista. "Scientists turn skin cells into neural precursors, bypassing stem-cell stage." Stanford School of Medicine. n. page. Print.

Morgan, David. The Cell Cycle: Principles of Control. New Science Press, 2007.
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What Does the Cell Do in the Body

Words: 656 Length: 2 Pages Document Type: Essay Paper #: 39080830

Cell is important because it is the building block of the body. It is a replicating organism that has proteins and cytoplasm and nucleic acids inside a membrane Alberts (2002). Cells are in everything from humans to plants, though each representation of life has its own particular cells. Cells are very small and impossible to see with a microscopic lens. That is why the cell was not actually noticed until such technology came along in the 17th century. Indeed, the name cell, which means small room in Latin, comes from the discoverer of the cell, who thought they looked like the small rooms that monks in the medieval era used to live in, which were called cells (Karp, 2009). Essentially, all living organisms are made up of cells and if there were no cells there would be no life. So the cell is very important.

What do cells do? That…… [Read More]

References

Alberts, B. (2002). Molecular Biology of the Cell. UK: Taylor and Francis.

Karp, G. (2009). Cell and Molecular Biology. UK: Wiley and Sons.
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Ethics Surrounding Human Embryonic Stem

Words: 5907 Length: 14 Pages Document Type: Essay Paper #: 434586

Although these stem cells are only a few years old, they possess unlimited potential in terms of clinical research. Specifically, scientists are focusing their potential uses in transplant medicine in order to significantly reduce the level of both infections and overall organ rejection in organ transplant surgery.

The potential for using stem cells is of vast clinical and medical importance. These cells could potentially allow scientists to learn what occurs at the cellular and molecular levels of human development and use this information to identify certain molecular pathways that contribute to a variety of conditions. Furthermore, using these stem cells could also allow scientists to discover the genes that are triggered in response to certain cellular conditions that cause rapid, unchecked cell growth or irregular cellular patterns. Additionally, using stem cells to discover certain genetic conditions will lend immense amount of information to the scientists and afford researchers the opportunity…… [Read More]

References

Bellomo, M. (2006). The Stem Cell Divide: The Facts, the Fiction, and the Fear Driving the Greatest Scientific, Political, and Religious Debate of Our Time. New York: Amacom.

Bevington, Linda K., Ray G. Bohlin, Gary P. Stewart, John F. Kilner, and C. Christopher Hook. Basic Questions on Genetics, Stem Cell Research and Cloning: Are These Technologies Okay to Use? Grand Rapids: Kregel, 2002.

Carrier, Ewa, and Gracy Ledingham. 100 Questions & Answers about Bone Marrow and Stem Cell Transplantation. Sudbury, MA: Jones and Bartlett, 2004.

DeGette, Diana. Sex, Science, and Stem Cells: Inside the Right Wing Assault on Reason. Guilford, CT: Lyons, 2008.
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Healthcare Discussion Response Embryonic Stem

Words: 398 Length: 1 Pages Document Type: Essay Paper #: 39943588



Discussion Response: Abortion don't think abortion should be ethical dilemma for 'Americans,' but only for the American women contemplating an abortion. No woman (or at least, hardly any woman) considers having an abortion lightly. It is a personal, not a political decision. No government can make a decision that a woman must go through the pain, stress, and emotional and physical trauma of an unwanted pregnancy. But no father can, either. Could a father compel a woman he impregnated to risk her life, but not his, in a pregnancy (because all pregnancies carry some risk)? Could he force a woman to have an abortion she did not want, because he did not want to have a child? After birth, the parents have equal rights over the life of their child. But before birth, in a world where visibly unwed mothers are still prohibited in some areas from going to the…… [Read More]

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Artificial Cell Building an Artificial

Words: 409 Length: 1 Pages Document Type: Essay Paper #: 90863799

Only if the cell can take in nourishment and excrete waste can the other components of the cell like the mitochondria engage in their essential tasks. hen a cell can take in nourishment and excrete wastes, this is the surest first sign of independent life

The problem is that the Cell-u-life Corporation wants an artificial cell that can do more than nourish itself. It wants a cell that can take the place of living stem cells and reproduce, and it is not certain of aerogels can do this. Thus another possibility is trying to create lipid-like structures to make cell membranes in the lab from fat cells in the body that do not come from human sources such as embryos but can reproduce like fat cells.

orks Cited

Team receives grant to study artificial cell membranes."(24 Aug 2005). Stanford News:

Press Release. Retrieved 3 Jun 2007 at h ttp://news-service.stanford.edu/news/2005/august24/aerogel-082405.html… [Read More]

Works Cited

Team receives grant to study artificial cell membranes."(24 Aug 2005). Stanford News:

Press Release. Retrieved 3 Jun 2007 at h ttp://news-service.stanford.edu/news/2005/august24/aerogel-082405.html
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Senescent Cells Are Essentially Cells

Words: 771 Length: 2 Pages Document Type: Essay Paper #: 28302829

When DNA is damaged, cells can react through cell cycle checkpoints which allows repair to begin before further division can occur. There is also the prokaryotic SOS response which changes gene expression in bacteria as a result of DNA damage. This response is regulated by the production of certain proteins. Moreover, eukaryotic cells also react to DNA damage through producing proteins that begin the process of DNA repair.

8. Mice are often the favored mammalian in the testing of aging interventions. This is often because of the fact that there are many mice easily available for testing but also the fact that "generation time is short" (Yuan et al. 2011). Essentially, the aging process and testing in interventions can be done on a much shorter time scale then with tests using monkeys.

9. Enzymes may change the transcription patterns of a cell by adding chemical groups to histone proteins. This…… [Read More]

References

Books. W.R. Clark. (2009). Human genetic diseases that mimic the aging process. Progeria? The Progeria Project Foundation. Web. http://www.progeriaproject.com/progeria/mimic.htm

Conboy, I.M., Conboy, M.J., Wagers, a.J., Girma, E.R., Weissman, I.L., & Rando, T.A. (2005). Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature, 17(433), 760-764.

Conti, Matteo. (2008). The Selfish Cell: An Evolutionary Defeat. Springer Publishing.

McClintock, D., Ratner, D., Lokuge, M. (2007). The mutant form of Lamin a that causes Hutchinson-Gilford Progeria is a biomarker of cellular aging in human skin. PLOS One, 2(2). Web. http://www.plosone.org/article/info:doi/10.1371/journal.pone.0001269
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Adipose Cells the Medical and

Words: 1574 Length: 5 Pages Document Type: Essay Paper #: 67763648

"Given the rising prevalence of obesity with age in both childhood and adult life, the prevalence of adult obesity cannot be predicted from childhood data, but increasing childhood obesity heralds a greater health burden in adult life"(James & al 2001, p. 232S). Thus, the future focus is on child obesity and how it can be treated to bring well-being for the adult.

esearch for adipose cells is not at the beginning, but has become increasingly intensive in the last years. Obesity is rapidly spreading across the globe but all the scientific breakthroughs won't do magic in the presence of disinterest and neglect towards the human body, so the first step should come from each individual.

eferences:

Albright, AL & Stern, JS 1998, "Adipose Tissue," Encyclopedia of Sports Medicine and Science, vol. 15

Bosello, O & al. 1980,"Adipose tissue cellularity and weight reduction forecasting," American Journal of Clinical Nutrition, vol. 33,…… [Read More]

References:

Albright, AL & Stern, JS 1998, "Adipose Tissue," Encyclopedia of Sports Medicine and Science, vol. 15

Bosello, O & al. 1980,"Adipose tissue cellularity and weight reduction forecasting," American Journal of Clinical Nutrition, vol. 33, no. 4, pp. 776-782

Gomillion, CT & Burg, KJL 2006, "Stem cells and adipose tissue engineering," Biomaterials, no. 27, pp. 6052 -- 606

Greenberg, AS & Obin, MS 2006, "Obesity and the role of adipose tissue in inflammation and metabolism," American Journal of Clinical Nutrition, vol. 83, no. 2, pp. 461-465
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Speech Understanding Ototoxicity Characteristics the Disease Stems

Words: 1116 Length: 3 Pages Document Type: Essay Paper #: 45592810

Speech

Understanding Ototoxicity

Characteristics

The disease stems from toxic reactions to structures of the ear, including the cochlea, vestibule, semicircular canals and otoliths. Drug-induced damage to these structures of the auditory and balance system can result in hearing loss, tinnitus, disequilibrium or dizziness (yback 2007).

Etiology

The propensity of specific classes of drugs to cause ototoxicity has been well established and over 100 classes of drugs have been associated with ototoxicity. Hearing loss can be temporary but is usually irreversible with most agents. Generally, antibiotic-induced ototoxicity is bilaterally symmetrical, but it can be asymmetrical. The usual time of onset is often unpredictable, and marked hearing loss can occur even after a single dose (Ishiyama 2006). Additionally, hearing loss may not manifest until several weeks or months after completion of antibiotic or anti-neoplastic therapy (Dille 2003). Vestibular injury is also a notable adverse effect of aminoglycoside antibiotics and may appear early…… [Read More]

References

Campbell KC, Durrant J. (1993) Audiologic monitoring for ototoxicity. Otolaryngol Clin North Am. 26(5): 903-14.

Dille M., et al. (2010). Ototoxicity risk assessment combining distoration product otoacoustic emissions with a cisplatin dose model. J. Of the Accoustical Society of America. 128(3): 1163-1174.

Fausti S., et al. (2009). Auditory and vestibular dysfunction associated with blast-related traumatic brain injury. Journal of Rehab Research and Development. 46(6): 797-810.

Grant KW, et al. (1998). Auditory-visual speech recognition by hearing-impaired subjects: consonant recognition, sentence recognition and auditory-visual integration. Journal of the Acoustical Society of America. 103(5): 2677-2690.
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Regenerative Medicine Healing Thy Self

Words: 1014 Length: 3 Pages Document Type: Essay Paper #: 10626599

How long this process takes and whether it will prevent the loss of seeded cells probably depends to a significant extent on the surrounding tissue and therefore represents another unknown.

HIF-1? And VEGF are also involved in osteogenesis, so the influence of these growth factors on the differentiation choices being made by the seeded stem cells is unknown (Polzer 7). The impact of prolonged hypoxic conditions on the seeded cells is another. Although Polzer and colleagues examined the timing of cell seeding relative to prevascularization, they discovered that the artificial scaffold rapidly filled with connective tissue. This process effectively clogged the matrix and prevented efficient seeding.

By comparison, researchers conducting spinal cord injury research into the efficacy of regenerative medicine techniques have been producing promising results (Sykova et al. 1113-1114). Hydrogels seeded with mesenchymal stem cells or bone marrow stem cells have produced positive results in both animal models and…… [Read More]

Works Cited

Park, Alice. "Cancer Patient Received a Man-Made Windpipe." Time.com, 12 Jan. 2012, Online. Internet. 1 Jul. 2013. Available  http://healthland.time.com/2012/01/13/cancer-patient-receives-a-man-made-windpipe/ .

Polzer, Hans et al. "Comparison of Different Strategies for in Vivo Seeding of Prevascularized Scaffolds." Tissue Engineering: Part C, published online May 21 ahead of print. Online.

Sifferlin, Alexandra. "Toddler gets New Windpipe from Her Own Stem Cells." Time.com, 1 May 2013, Online. CNN.com. Internet. 1 Jul. 2013. Available  http://www.cnn.com/2013/05/01/health/toddler-stem-cells-windpipe .

Sykova, Eva et al. "Bone Marrow Stem Cells and Polymer Hydrogels -- Two Strategies for Spinal Cord Injury Repair." Cellular and Molecular Neurobiology 26.7-8 (2006): 1113-1129.
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Biology and Technology in the Real World

Words: 775 Length: 2 Pages Document Type: Essay Paper #: 60692352

Stem Cells

Hello, my friend. I am truly sorry and sympathize as much as I can regarding your traumatic car accident and subsequent spinal injury. I appreciate that you have kept me abreast of your treatment options. Your team of physicians agree that you would be a fine candidate for treatment specifically with stem cells. Most people have heard of stem cells and are aware of the scientific and ethical controversies surrounding them, but not as many people have performed productive research to find out what they really are and what the possible medical applications (and pitfalls) that come with stem cells. I have taken it upon myself to do some research for you, so that you are in a better position to make a more informed decision regarding this option for treatment of your spinal cord injury. In the next couple of pages, I will do my best to…… [Read More]

References:

Mayo Clinic. (2013). Stem Cells: What They Are and What They Do. Mayo Clinic, Web, Available from: http://www.mayoclinic.com/health/stem-cells/CA00081. 2013 May 31.

National Institute of Health. (2013). Basic Questions about Stem Cells. NIH, Web, Available from:  http://stemcells.nih.gov/research/Pages/Default.aspx . 2013 May 31.
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Bioethical Dilemma Research With Embryonic

Words: 824 Length: 2 Pages Document Type: Essay Paper #: 17944612

2). Stem cells "can theoretically differentiate into virtually any type of human cell, from blood cells to skin cells" (AAAS, 2009). Besides, "in the natural reproductive process, human eggs are often fertilized but fail to implant in the uterus" (AAAS, 2009).

From an ethical standpoint, proponents of stem cell research also argue that embryos are going to 'waste.' "Fertilization clinics routinely create more human embryos than are needed over the course of a fertility treatment, and are therefore left with excess embryos that are often simply discarded" (AAAS, 2009). Some individuals who are philosophically opposed to both abortion and artificial reproductive technology believe so long as such practices are legal the remaining embryos should be used to have at least some impact upon the improvement of human life. Other "opponents object to this argument, however, saying that such research would still condone the destruction of embryos" and encourage more 'waste,'…… [Read More]

References

AAAS Policy Brief: Stem Cell Research. (2009). AAAS (American Association for the Advancement of Science). Retrieved June 16, 2010 at http://www.aaas.org/spp/cstc/briefs/stemcells/#ethical

Eustice, Carol & Richard Eustice. (2006, November 17). Stem cell research: Understanding the issue. About.com Guide. Retrieved June 16, 2010 at http://arthritis.about.com/od/stemcell/i/stemcells.htm

Genesis. (2010). Bible.com. Retrieved June 16, 2010 at http://www.bibleontheweb.com/Bible.asp

Stem cell basics. (2010). National Institute of Health. (NIH). Retrieved June 16, 2010 at http://stemcells.nih.gov/info/basics/basics5.asp
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Sickle Gene Therapies for Sickle

Words: 1128 Length: 4 Pages Document Type: Essay Paper #: 95693355

Implications for ongoing research into genetic therapies and side effects/later developments are discussed at length.

Yannaki, E. & Stamatoyannopoulos, G. (2010). Hematopoietic stem cell mobilization strategies for gene therapy of beta thalassemia and sickle cell disease. Annals of the New York Academy of Sciences 1202: 59-63.

Though the clinical trial these two researchers are involved in does not yet have results that are ready for publication, the review of the risks they provide regarding the use of stem cell mobilization with G-CSF in patients with sickle cell is highly useful information. So, too, is the practice of pre-treating patients with hydroxyurea before administering the stem cell treatment, which the authors describe in detail and which forms the basis of the related clinical trial. Potential reduction of risks appears to be quite promising, though final results from the clinical trial and other supporting evidence will of course be required.

Ye, L.,…… [Read More]

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A Brief Overview of the

Words: 388 Length: 1 Pages Document Type: Essay Paper #: 44940819

Though
this is, of course, never the case, anti-stem cell research activists
affiliate this issue as a slippery slope with the abortion issue.
However, to my perspective, this is an incredibly inhumane
politicization of a prospect which could save many lives and reduce much
suffering. Obstruction to advancement in this field are short-sighted and
cruel. The condition of cystic fibrosis is a good example of a condition
where the effective use of embryonic stem cell research would be considered
a means to reducing much pain in its sufferers. Here, the dysfunction of
the secretory glands creates excessive mucous production and can result in
life-shortening respiratory and developmental issues. If embryonic stem
cells are differentiated and transplanted to produce healthy, functional
secretory glands in the sufferer, this serious and distressful condition
could be diminished in presence.
This denotes the potentially broad-based benefits to pushing forward
with research, in spite of the…… [Read More]

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Philosophy Required in High School

Words: 1096 Length: 3 Pages Document Type: Essay Paper #: 75998237

Obama endorsed an Illinois handgun ban while he was serving in the Illinois state legislature and also supports a ban on semi-automatic weapons. However, the current President professed his support for the Second Amendment, stating that he supports restrictions to keep guns out of the wrong hands, not a full prohibition. In Illinois he co-sponsored a 2000 to limit consumer purchases of firearms to one gun per month -- although he also supported 'conceal carry' laws for retired police officers ("Gun control," on the Issues, 2008).

The spike in gun sales has more to do with political posturing than reality: gun owners wish to demonstrate their opposition to Obama's system of values, as conceptualized in the red-blue divide that currently exists in the United States. In this polarized media positioning, Obama represents urban elitism and government control, despite his actual policies. The NRA and the gun industry has used this…… [Read More]

Works Cited

"Gun control." On the issues. 2008. June 5, 2010.

 http://www.ontheissues.org/gun_control.htm 

Kinzie, Susan. "GWU adds ethical focus to business school." The Washington Post.

September 15, 2008. June 5, 2010.  http://www.washingtonpost.com/wp-dyn/content/article/2008/09/15/AR2008091502975.html
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Cellular Function and Aging Tumor Suppression Protein

Words: 2307 Length: 6 Pages Document Type: Essay Paper #: 72336870

Cellular Function and Aging

Tumor Suppression Protein 53 and Effects on Cellular Function and Aging

The concept of aging has many intrinsic and extrinsic factors that act as markers on an individual organism. Ignoring mortality associated with external environmental factors, very few organisms can be said to have cellular immortality with no decrease in cellular function or repeat division in normal diploid cells. Cellular senescence is a normal process that halts cellular division after a set of cycles of replication. Senescent cells can remain completely functional but lose the programmed process of replication. The normal pathway for senescent cells is either aging with metabolic pathways continuing for the cell or programmed cell death which is known as apoptosis that occurs when cellular function changes, a specific lifetime is reached for the cell or the cell is damaged. The multicellular cnidarians known as a Hydra has been shown to have a…… [Read More]

References

Cappisi, J. (2005) Senescent cells, tumor suppression and organisimal aging: good citizens, bad neighbors. Cell 120 1-10.

Coppe, J.P. Patil, C.K. Rodier, F. Sun, Y. Munoz, D.P. Goldstein, J. Nelson, P.S. Desprez, P. Campisi, J. (2008) Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous functions of Oncogenic RAS and the p53 Tumor Suppressor. PLOS Biology, 6-12, 2853-2868

Faragher, R.G. (2000) Cell senescence and human aging: where's the link? Biochemical Society Transactions 28 221-226.

Kirkwood, T.B. Austad, S.N. (2000) Why do we age? Nature 408. 233-238.
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B And T Lymphocytes the Biology of

Words: 1265 Length: 4 Pages Document Type: Essay Paper #: 69729583

B and T. Lymphocytes

The Biology of B. And T. Lymphocytes and the eactions between Them

The Biology of B. Lymphocytes

B lymphocytes originated in 1960s and 1970s era through experiments conducted in animal models, clinical evaluation of patients having immune system diseases, and the nascent technology of cell surface molecule characterization. In fact, the origin of B. And T. lymphocytes took place simultaneously. The differentiation of the haematopoietic stem cells gives birth to the formation of common lymphoid progenitors, which actually generate B. lymphocytes. They are generated and developed in yolk sac, fetal liver, and the adult liver present in the body (Austyn & Wood, 1994). B lymphocytes are present in areas that come in close contact with foreign substances. They act as defensive mechanism against invading microorganisms, viruses and parasites and play a vital role in humoral immune response. Since these cells originate in the Bone marrow, they…… [Read More]

References

Austyn, J., M. And Wood, J., K. (1994). Principles of Cellular and Molecular Immunology. New York: Oxford University Press.

Beltman, J., B., Maree, A. & Boer, R. (2007), Spatial modelling of brief and long interactions between T cells and dendritic cells, Australian Society for Immunology, Pp. 1-9, Retrieved October 14, 2012.

House, B., R. & Descotes, J. (2010), Cytokines in Human Health: Immunotoxicology, Pathology,

and Therapeutic Applications (Methods in Pharmacology and Toxicology), New