Cholecystitis
Biliary colic and cholecystitis are in the spectrum of gallbladder disease, ranging from asymptomatic gallstones to biliary colic, cholecystitis, choledocholithiasis, and cholangitis (Santen pp). When gallstones temporarily obstruct the cystic duct or pass through into the common bile duct, gallstones become symptomatic and biliary colic develops, however, if the cystic duct or common bile duct becomes obstructed for hours or gallstones irritate the gallbladder, then cholecystitis develops, and when the stones become lodged in the common bile duct, choledocholithiasis occurs, resulting in possible cholangitis and ascending infections (Santen pp).
Cholecystitis is an inflammation of the gallbladder caused by obstruction, usually a gallstone, of the cystic duct, and the inflammation may be sterile or bacterial and the obstruction may be acalculous or caused by sludge (Santen pp). Bacterial infection is believed to be a consequence, not a cause, of cholecystitis, approximately 75% of bile cultures are positive, with the most common organisms being Escherichia coli, Klebsiella species, and enterococci (Santen pp). Common bile duct stones, choledocholithiasis (10%), "are either secondary (from the gallbladder) or primary (formed in bile ducts)" (Santen pp).
Acute cholecystitis most often caused by a gallstone that cannot pass through the bile duct (Cholecystitis pp). Pain is felt in the right upper part of the stomach, and there may be nausea, vomiting, belching, and intestinal gas, flatulence (Cholecystitis pp). Diagnosis usually made with x-rays, is useful in ruling out appendicitis, intestinal obstruction, peptic ulcer, and other upper stomach disorders, and surgery is the usual treatment (Cholecystitis pp). Chronic cholecystitis is the more common type and has a slower beginning, with pain, often felt at night following a fatty meal (Cholecystitis pp). Complications include gallstones, disease of the pancreas, and cancerous growth (carcinoma) of the gallbladder, and usually corrected by surgery (Cholecystitis pp).
In roughly 90% of cases, acute cholecystitis is caused by gallstones in the gallbladder, which obstruct the duct leading from the gallbladder to the common bile duct, which drains into the intestine, however, severe illness, alcohol abuse, and, although rare, tumors of the gallbladder...
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