Dioxin And Human Health The Exposure Of Essay

Dioxin and Human Health The exposure of dioxins and humans occur through a variety of avenues, but in particular, it is through dietary means. In particular, such contamination occurs through the consumption of milk, dairy products, fish, and meat. The effects due to dioxin "include enzyme induction, immunotoxicity, developmental effects" (Kogevinas, 331), which are all dependent whether exposure is acute or chronic. The positive correlation between medical and health effects, and dioxin revelation result in elevated incidences of cancer and non-cancerous illnesses and conditions.

The documented occurrences between cancer mortality and people affected from exposure of dioxins are in a positive manner. In both, males and females, there were incidences of contaminants affects the neoplasms of the lymphatic and hematopoietic system. There were elevated risks for breast cancer in both sexes, along with endometrial cancer and testicular cancer. There has been an excess risk for cancer in other endocrine organs, and people died from tumors of the suprarenal glands. Furthermore, there have been increased risks in individuals having lymphoma, multiple myeloma, soft-tissue sarcoma, lung cancer, liver cancer, and endometrium. Those who were exposed to dioxins two or three times more than recommended were the group with the greatest health risk.

In a study led by Bertazzi, involving a twenty-year mortality study after inhabitants were exposed to dioxins in Seveso, Italy, such aforementioned carcinogenic health effects were observed. The investigation involved people in high-exposed zones, which were labeled as A and B. In zone A, there was one who died from melanoma, and two from non-Hodgkin's lymphoma. As well, there was a significant increase in chronic obstructive pulmonary disease or COPD. In the 5-9-year period, there was an increase in mortality due to digestive, lung, myeloma, and bladder cancer, and there was a death due to circulatory disease. After fifteen years, there was a significant increase in lung cancer and non-Hodgkin's lymphoma. In the 1-10-year period, there was an elevated incidence of circulatory disease, and after the incidence, mortality increased from respiratory disease, but mostly due to COPD. In females exposed to dioxins in zone A, there was an excess occurrence of myeloma, colon, and other digestive cancers. In the second decade, there...

...

Furthermore, there was an elevated risk for hypertension and COPD. In males, there was an increase in mortality rate due to lung cancer, and there were suggestive elevated risks for non-Hodgkin's lymphoma and rectal cancer. As well, after fifteen years, men experienced an increased incidence of respiratory disease.
In zone B, inhabitants endured an increased occurrence of rectal cancer, and significant elevated incidence of Hodgkin's disease, multiple myeloma, and myeloid leukemia. However, there was a moderate increase in diabetes and chronic ischemic heart disease. In the 5-9-year period, individuals experienced lung cancer and other digestive cancers, along with an increase in Hodgkin's disease. Furthermore, the occurrence of non-Hodgkin's disease revealed a modest increase but at a later period. In the 15-20-year period, Bertazzi's research revealed two who died from melanoma, thus resulting in a high risk ratio. The observation period exposed the consistent mortality increase due to conditions related to lymphatic and hemopoietic neoplasms. The risk of multiple myeloma was increased in the 5-9-year period, and also in the 10-14-year period. The number of deaths due to leukemia was above expectations, while myeloid leukemia was at its highest in the longest latency period. In the 5-9-year period, it was reported there was an increase in the incidences of diabetes, COPD, and chronic ischemic heart disease. In the 10-14-year period, there was an elevation in digestive cancers, especially in stomach and liver cancer. As well, there were twelve cases of lymphatic and hemopoietic neoplasms occurrence, along with an increase in mortality due to Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, and leukemia. In the 10-15-year period, there was a moderate increase in COPD, and after fifteen years, diabetes occurred in abundance. At the end, males experienced a moderate increase in mortality due to cancer, especially rectal cancer. As for females, the mortality rate was due to digestive cancers.

In both zones, the 0-10-year period, there was an elevated rate of Hodgkin's disease. In the 5-10-year period, mortality rate peaked due multiple myeloma, while in the longest latency period; incidences were high for non-Hodgkin's lymphoma and…

Sources Used in Documents:

Works Cited

Bertazzi, P, D Consonni, S Bachetti, M Rubagotti, A Baccarelli, C Zocchetti, and A Pesatori . "Health effects of dioxin exposure: a 20-year mortality study." American Journal of Epidemiology 153.11 (2001): 1031-1044. Print.

"Dioxins and their effects on human health." WHO-World Health Organization. WHO-World Helath Organization, n.d. Web. 11 Apr. 2011. .

Kogevinas, M. "Human health effects of dioxins: cancer, reproductive and endocrine system effects." Human Reproduction Update 7.3 (2001): 331-339. Print.

Suskind, R, and V Hertzberg. "Human Health Effects of 2,4,5-T and Its Toxic Contaminants." Journal of American Medical Association 251.18 (1984): 2372-2380. Print.


Cite this Document:

"Dioxin And Human Health The Exposure Of" (2011, April 11) Retrieved April 25, 2024, from
https://www.paperdue.com/essay/dioxin-and-human-health-the-exposure-of-50455

"Dioxin And Human Health The Exposure Of" 11 April 2011. Web.25 April. 2024. <
https://www.paperdue.com/essay/dioxin-and-human-health-the-exposure-of-50455>

"Dioxin And Human Health The Exposure Of", 11 April 2011, Accessed.25 April. 2024,
https://www.paperdue.com/essay/dioxin-and-human-health-the-exposure-of-50455

Related Documents

The team analyzed samples for carcinogen-DNA adducts, biomarkers associated with increased cancer risk, and cotinine, a measure of secondhand tobacco smoke exposure. Based on prior findings in animal models, scientists believe only one-tenth of the dose of PAH passes from the mother to fetus through the placenta. Even so, the investigators found that newborns incurred DNA damage at a rate slightly higher than their mothers" (Wood, 2006). In other

Nevertheless, an individual may prefer to have this type of calculus removed for other reasons or otherwise as part of a long-term treatment regimen. For example, Bennett and Mccrochan note that, "When the American Dental Association later approved Warner-Lambert's mouthwash, Listerine, by stating that 'Listerine Antiseptic has been shown to help prevent and reduce supragingival plaque accumulation and gingivitis. . ., ' sales rose significantly" (1993:398). It remains unclear,

FARMED vs. WILD SALMON research, identify discuss basic roles HRM (Human Research Managers) professionals, explain roles changed years. Should I eat farm-raised salmon or wild salmon? Fish has grown increasingly popular as a source of protein for American consumers, and salmon is particularly in demand. Salmon is a fatty fish with a great deal of umami, and can satisfy the palate of even the most dedicated red meat eater. From a health standpoint,

This approach has been regarded as one of the best and safest approaches. Despite this, there is widespread concern about proper radioactive waste management. (National Research Council (U.S.), 1) According to a 1976 ERDA report, the nine facilities for radioactive waste disposal have been referred to as significant health hazards. Leaks and spills at such facilities are not very uncommon. In fact, the radioactive waste storage facility at Richland has

GTD includes hydatidiform mole or HM and choriocarcinoma. HM develops complications of pregnancy and the main factor to choriocarcinoma, which is a highly malignant cancer. HM starts during fertilization and is either complete or partial, according to histopathologic and cytogenetic criteria. In a complete HM, there is no embryo, no umbilical cord and no amniotic membranes. The chorionic villi of the trophoblastic tissues and chromosomal constitution are all abnormal. Published

Medical Science
PAGES 10 WORDS 2880

Chemical Substances on Liver and Kidney Enzymes and Tissues A number of common consumer products and foods contain toxic substances that can have an adverse effect on liver and kidney enzymes and tissues (Steenland & Fletcher 2010). In addition, a number of naturally occurring and artificial substances contain toxic elements that are harmful to these organs (Steenland & Fletcher 2010). In this regard, Satarug and Nishjo (2004, p. 1512) report