Concept maps of breast cancer and benign prostatic hyperplasia etiology and diagnosis
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¶ … Map of Benign Prostatic Hyperplasia and Breast Cancer
Lifestyle
Eating Better
Cutting down on alcohol
Giving up Tobacco
Exercising
Controlling Stress
Medications/Surgical
Medications approved to treat breast cancer:
Abitrexate
Abraxane
Ado-Trastuzumab Emtansine
Afinitor et al. (National Cancer Institute, 2016).
Concept Map of Benign Prostatic Hyperplasia and Breast Cancer
Breast Cancer
ETIOLOGY
Primary
The etiology of breast cancer remains mainly unidentified. Risk factors linked with breast cancer can be clustered into three comprehensive contributing factors: i. family history (hereditary) factors, ii. hormonal reproductive factors
environmental factors (DeBruin and Josephy, 2002).
Secondary
Polymorphisms of drug-metabolizing enzymes may influence risk of breast cancer from environmental chemicals, dietary agents, and endogenous steroids (DeBruin and Josephy, 2002).
BREAST CANCER
DIAGNOSIS
History/Physical
Lump or contour change
Skin tethering
Nipple inversion
Dilated veins
Ulceration
Paget disease
Edema or peau d'orange (Medscape, 2015)
Diagnostic/Lab Tests
Chest x-ray (CXR) Complete blood count (CBC)
Basic metabolic panel (BMP)
Lactate Urine analysis (UA)
Urine culture (UC)
Blood cultures x2 sites (Rischer, 2013)
PATHOGENESIS
Secondary
Contrivance of carcinogenesis continues to be mostly unidentified, but overexpression is linked with speedy tumour growth, reduced survival, increased risk of relapse subsequent to surgery, and poor reaction to conventional chemotherapeutic agents (Yager and Davidson, 2006).
CLINICAL MANIFESTATIONS
Signs
Refutation, or inward turning of the nipple
Amplification of one breast dimpling of the breast surface
An prevailing lump that gets bigger
An "orange peel" texture to the skin
Vaginal discomfort
Unpremeditated weight loss enlarged lymph nodes in the armpit
Perceptible veins on the breast (Krans and Cafasso, 2015)
Symptoms
Thickening of the breast tissue
Nipple discharge
Redness or scaling of the nipple
A nipple that retracts or turns inward
Unexplained redness, swelling, skin irritation, itchiness, or rash on the breast (Krans and Cafasso, 2015).
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