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Key Global Health Actors: WHO, CDC, MSF, and Beyond

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Abstract

This paper surveys the principal actors shaping global health policy and practice, spanning international organizations, national governmental agencies, and nongovernmental organizations. It examines the founding missions and landmark achievements of the United Nations and the World Health Organization, including smallpox eradication and polio near-elimination. It then profiles two national agencies—the U.S. Centers for Disease Control and Prevention and Public Health England—before turning to nongovernmental actors such as Doctors Without Borders and the Bill and Melinda Gates Foundation. Throughout, the paper connects these organizations to the DNP Essentials, highlighting the role advanced practice nurses can play within complex, collaborative global health systems.

Key Takeaways
  • Introduction to Global Health Actors: Overview of major global health actors and DNP Essentials
  • The United Nations (UN): UN founding, mission, and key accomplishments
  • The World Health Organization (WHO): WHO history, disease eradication, and pandemic response
  • National Governmental Health Agencies: CDC and Public Health England profiles
  • Nongovernmental Organizations: MSF and Gates Foundation roles and achievements
  • Summary and Implications for Advanced Practice Nursing: Synthesis and nursing leadership in global health
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What makes this paper effective

  • Provides a clear, organized taxonomy of global health actors—international, national governmental, and nongovernmental—giving readers a logical framework for understanding the landscape.
  • Anchors the discussion in a professional nursing context by consistently referencing the DNP Essentials, connecting abstract organizational roles to clinical and leadership practice.
  • Balances breadth and specificity: each organization receives its own founding context, mission statement, and at least one concrete accomplishment, making the survey both comparative and substantive.

Key academic technique demonstrated

The paper demonstrates effective use of organizational profiling as an analytical structure. Rather than producing a general narrative, the author constructs parallel profiles—origin, mission, accomplishments—for each actor, enabling implicit comparison across the six organizations discussed. This technique helps readers evaluate similarities and differences without requiring the author to explicitly argue for a ranking or hierarchy.

Structure breakdown

The paper opens with a broad introductory section that maps the global health landscape and situates the discussion within the DNP Essentials framework. It then moves through three tiers of actors in sequence: international bodies (UN and WHO), national agencies (CDC and PHE), and nongovernmental organizations (MSF and the Gates Foundation). A brief concluding summary ties the organizational survey back to the role of advanced practice nurses. This funnel-then-widen structure—broad landscape, specific profiles, nursing implications—keeps the argument coherent across six distinct organizations.

Introduction to Global Health Actors

The global health landscape is characterized by a variety of prominent actors, each with distinct yet intertwined roles in promoting health, preventing disease, and managing health crises worldwide. The United Nations (UN) works toward international peace and security, fostering friendly relations among nations and promoting social progress, better living standards, and human rights—which inherently includes health. Its specialized agency, the World Health Organization (WHO), is explicitly committed to promoting health, keeping the world safe, and serving vulnerable populations. It has led significant strides in disease eradication and prevention, including the eradication of smallpox and the near-eradication of polio, and has been a major actor in global health crises such as the COVID-19 pandemic.

National governmental health agencies like the U.S. Centers for Disease Control and Prevention (CDC) and the UK's Public Health England (PHE) work to safeguard their respective nations' health by preventing and managing disease outbreaks and health emergencies and promoting healthier lifestyles. Nongovernmental health organizations, such as Doctors Without Borders (Médecins Sans Frontières, MSF) and the Bill and Melinda Gates Foundation, also play essential roles. These organizations can often fill gaps not covered by governmental bodies, offering vital healthcare services in crises, promoting healthcare research, and aiming to eliminate specific diseases globally.

The DNP Essentials illustrate the importance of understanding and working within the global health environment. Essential II, "Organizational and Systems Leadership for Quality Improvement and Systems Thinking," is especially pertinent, as these organizations must continually strive for better health outcomes and navigate complex health systems. Essential VI, "Interprofessional Collaboration for Improving Patient and Population Health Outcomes," is also highly relevant, as these actors must collaborate across disciplines and sectors to tackle global health challenges. Essential VIII, "Advanced Nursing Practice," emphasizes the role of advanced practice nurses in these contexts, using their skills to promote health and wellness at both individual and population levels.

The United Nations (UN)

Founded in 1945 following the end of World War II, the United Nations was established with the primary goal of maintaining international peace and security (Thakur, 2016). War had caused much of the world to suffer deeply, and the UN's aim was to prevent any such catastrophe from occurring again. It also sought to serve as a governing body through which friendly relations among nations could be fostered. Numerous UN conventions established rules by which member nations were expected to govern themselves. Additional goals included the promotion of social progress, better living standards, and human rights.

Over its history, the UN has accomplished a number of important objectives. One of its central goals was to end colonization, and to date it has successfully helped more than 80 colonies gain independence. It created a framework for responding to global crises and conflicts—the UN Peacekeeping Forces were awarded the Nobel Peace Prize in 1988—launched the Sustainable Development Goals to end poverty and protect the planet, and coordinated humanitarian aid during crises and disasters worldwide (Harff, 2018).

Over its nearly eight-decade history, the United Nations has been involved in over 70 peacekeeping missions worldwide, helping manage or end conflicts and facilitating post-conflict reconstruction. One of its landmark achievements is the adoption of the Universal Declaration of Human Rights in 1948 by the UN General Assembly. This document laid the foundation for fundamental human rights that ought to be universally protected.

The World Health Organization (WHO)

The World Health Organization was established on April 7, 1948, as a specialized agency of the United Nations, with the primary goal of promoting health and serving vulnerable populations. The WHO directs and coordinates authority on health within the UN system, aiming to lead partners in global health responses.

One of the WHO's major early accomplishments was the eradication of smallpox. Smallpox was an infectious disease with a significant mortality rate that caused severe illness in survivors. The eradication campaign ran from 1967 to 1980, with the WHO declaring smallpox eradicated on May 8, 1980—marking the first disease ever eliminated through coordinated human effort. The WHO has also been instrumental in the near-eradication of polio. Polio, short for poliomyelitis, is a disabling and life-threatening disease caused by the poliovirus. The WHO launched the Global Polio Eradication Initiative in 1988, and since then the incidence of polio has decreased by over 99%. Only two countries, Afghanistan and Pakistan, continue to experience wild poliovirus transmission.

The organization has also made substantial strides in controlling other communicable diseases. It launched the "3 by 5" initiative in 2003, which aimed to provide three million people living with HIV/AIDS in low- and middle-income countries with antiretroviral treatment by the end of 2005 (Van Damme et al., 2006). It has led the battle against Ebola through its Health Emergencies Programme, working with countries to strengthen their capacity to prevent and respond to outbreaks. The WHO has also been pivotal in the fight against malaria, a life-threatening disease transmitted through the bites of infected female Anopheles mosquitoes, providing a wide range of tools to prevent, diagnose, and treat the disease and contributing to significant reductions in malaria cases and deaths. During the recent COVID-19 pandemic, the WHO played a crucial role in coordinating the global response, providing timely information and guidelines, supporting research efforts, and working to ensure equitable access to diagnostics, treatments, and vaccines.

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National Governmental Health Agencies130 words
The CDC was established in 1946 with the goal of protecting public health and safety through the control and prevention of disease, injury, and disability in the U.S. and internationally. Among its major accomplishments, the CDC played a vital…
Nongovernmental Organizations140 words
Founded in 1971, Doctors Without Borders provides emergency medical aid in areas where it is needed most, including conflict zones and in response to epidemics and natural disasters (Fox, 1995). Among its notable accomplishments, MSF won the Nobel Peace Prize in…
Summary and Implications for Advanced Practice Nursing120 words
In summary, global health is an interconnected field managed by a broad array of actors that play crucial roles in promoting health, preventing diseases, and handling global health crises. These actors include international organizations like the United Nations and its…
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Key Concepts in This Paper
Global Health Actors Disease Eradication DNP Essentials WHO Initiatives Public Health Agencies Humanitarian Medicine Interprofessional Collaboration Nongovernmental Organizations Pandemic Response Health Inequalities
Cite This Paper
PaperDue. (2026). Key Global Health Actors: WHO, CDC, MSF, and Beyond. PaperDue. https://www.paperdue.com/study-guide/global-health-actors-who-cdc-msf-2178464

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