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Structure and Function of the P53 as a Tumor Suppressor
Words: 1740 Length: 7 Pages Document Type: Research Paper Paper #: 48537246
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Tumor Suppressor p53
The p53 tumor suppressor, also known as the TP 53 or tumor protein can be referred to as a gene that codes for a protein that is responsible for the regulation of the cycle of the cell and therefore acting as tumor suppression. It is significant for cells in multicellular organisms to suppress cancer, p53 has been referred to as ‘the guardian of the genome’ as extracted from its role in the conservation of the stability by hindering the mutation of the genome. The name p53 comes from the molecular mass that it has-53 kilodalton fraction of the cell proteins.
The research conceited with the cure for cancer and its management dates many decades ago, but in 1979 there was a significant breakthrough. There were six groups of investigators each working separately and independent of each other came to an amazing similar discovery of a 53 kDa…

Bioinformatics (2017). Primary Information of p53. Retrieved November 24, 2017 from
Hollstein M. and Harris C.C., (1993). Clinical Implications of the p53 Tumor-Suppressor Gene. Retrieved November 23, 2017 from
Freed-Pastor W.A. & Prives C., (2017). Mutant p53: one name, many proteins. Retrieved November 23, 2017 from
Nature Education, (2014). p53 : The Most Frequently Altered Gene in Human Cancers. Retrieved November 24, 2017 from

Analyzing the Eukaryotic Chromosome
Words: 653 Length: 2 Pages Document Type: Essay Paper #: 12450704
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Structural Elements of a Functional Eukaryotic Chromosome
The three essential structural elements of a functional eukaryotic chromosome are centromere, telomeres, and origins of replication. Centromere serves as the attachment point for the spindle fibers. A centromere is a region of DNA responsible for the movement of the replicated chromosomes into the two daughter cells during meiosis and mitosis. Joining the sister chromatids is one of the major functions of the centromere. The two copies of the replicated chromosome are referred to as sister chromatids, and they stay joined together until they are physically pulled into the two future daughter cells, which ensures that each daughter cell will receive exactly one copy of each chromosome. The second major function of the centromere is to attach the microtubules in the mitotic spindle. The centromere will direct the formation of the kinetochore. The kinetochore is a special protein structure that attaches to the…

Hamperl, S., & Cimprich, K. A. (2014). The contribution of co-transcriptional RNA: DNA hybrid structures to DNA damage and genome instability. DNA repair, 19, 84-94.
Hennig, W. (2013). Structure and Function of Eukaryotic Chromosomes. Heidelberg, Germany: Springer.

Membrane Transport
Words: 983 Length: 3 Pages Document Type: Research Paper Paper #: 64056224
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Mechanism of Membrane Transport
Describe the mechanism of membrane transport related to cellular intake and output
Membrane transport takes into account the gathering of mechanisms that facilitate the regulation of the passage of solutes like minute molecules and ions through membranes, which are lipid bilayers that comprise of proteins entrenched in them. The mechanisms that are usually involved in cellular intake and output are reliant on the characteristics of the substances that are meant to be transported. With respect to passive transport, miniscule, electrically charged molecules together with water, move easily through pores within the plasma membrane’s lipid layer. The other molecules are significantly massive to be transported through pores or are deemed to be ligands that are linked to receptors on the plasma membrane of the cell. Notably, a number of these molecules are transported in and out of the cell through active transport, which necessitates life, biologic activity…

Elgazzar, A. H. (2014). Synopsis of pathophysiology in nuclear medicine. New York: Springer.
Gozhenko, A. I., Gurkalova, I. P., Zukow, W., Kwasnik, Z., Mroczkowska, B., Zukow, W., & Kwasnik, Z. (2009). Pathology: Medical student\\\\'s library.
Klabunde, R. E. (2018). The Pharmacologic Treatment of Edema. Cardiovascular Pharmacology Concepts.
Kulbacka, J., Choroma?ska, A., Rossowska, J., We?gowiec, J., Saczko, J., & Rols, M. P. (2017). Cell Membrane Transport Mechanisms: Ion Channels and Electrical Properties of Cell Membranes. In Transport Across Natural and Modified Biological Membranes and its Implications in Physiology and Therapy (pp. 39-58). Springer, Cham.