Crohn's Disease Research Paper

Length: 5 pages Sources: 4 Subject: Disease Type: Research Paper Paper: #59206731 Related Topics: Crohns Disease, Lupus, Medical Terminology, Reproductive System
Excerpt from Research Paper :

Causes

Complications

Diagnosis

Latest discoveries

Crohn's disease, ileitis or enteritis is a medical condition that is known to cause inflammation of the digestive system also known as gastrointestinal (GI) tract. This condition affects any part of the gastrointestinal tract, starting from the mouth to the anus, but it mostly affecting the ileum (USFDA,2008). The inflammation may penetrate deep into the lining of the organs affected thereby causing pain making the intestines occasionally empty, resulting in diarrhoea.

Similarity in symptoms with other intestinal disorders, like irritable bowel syndrome and ulcerative colitis, makes Crohn's disease difficult to diagnose. Ulcerative colitis results in inflamed ulcers on the top lining of the large intestine while in Crohn's disease all the layers of the intestines are involved, and healthy bowel may be occur in between parts of the affected bowel. Other symptoms include, fever, unintentional weight loss, fatigue, tenesmus, and persistent, watery diarrhoea.

The disease is known to affect both genders in equal measures though it may be genetic thus 20% of people with Crohn's disease inherits it from blood relations with inflammatory bowel condition mostly a sibling or the parents It affects people of all age groups but is more pronounced in people of ages 20-30 and those of Jewish background in while it is less diagnosed in the African-American population (NDDIC, 2006).

Causes

Several hypotheses have been forwarded in an attempt to explain the causes of Crohn's disease. One such theory states that the immune system of people with this condition reacts exceptionally with food, bacteria, and other substance recognizing them as antigens therefore responding by attacking them. The white blood cells accumulate intestinal layers Another Theory states that either the body's reaction to the foreign substances or the substances themselves may be the root cause of inflammation and that the genes, the environment, the immune system and other factors may be responsible.

Environmental factors

It has been suggested that Crohn's

...

This is because it has for sometime been associated with an increased uptake of food containing animal protein as well as milk protein .The individuals who consumer foodstuffs containing vegetable proteins appear to have lowered incidences of the Crohn's disease

Immune system

The opinion that Crohn's disease is technically an autoimmune disorder of T cell means that it could be as a result of an impaired immune system (Marks & Segal,2008,p.263)

Complications

Crohn's disease has got several complications that may include the blocking of intestines due to thickening of the walls that is caused by swelling and scar tissues hence narrowing the passage. The condition is also responsible for sores and ulcers found on the affected parts and the surrounding tissues, like the bladder, reproductive system, and epidermis. Fistula is also one of the complications and may require medication and in some cases surgery. Fissures may also be found developing in the mucal membrane of the anus.

Nutritional complications are also familiar with Crohn's condition and may include deficiency of proteins, vitamins and calories. This is as a result of malabsorption, poor intake of diets and loss of proteins by the intestines. Other complications include; arthritis, skin/epidermal complications, eyes and mouth inflammation, kidney stones, gallstones, liver and biliary system problem.

Diagnosis

To diagnose Crohn's disease, physical examination and several clinical tests are carried out. These includes blood tests to look out if the patient suffers from anemia, which could in turn be indicative of intestinal bleeding, The tests may also reveal a high white blood cell count, which is a sign of inflammation in the gastrointestinal tract. Conducting stool sample tests may also indicate intestinal bleeding or infection. Albumin test may also be necessary when presented with symptom such as fatigue, weight loss, swelling around the eyes, belly and legs in order to distinguish the condition from diseases that present the same symptoms such as liver disorders and nephritic syndrome. A medical practitioner may also undertake an upper gastrointestinal test using barium solution and x rays in order to indicate presence of inflammation in the small intestines. Sigmoidoscopy and colonoscopy may also be conducted for visual examination of the colon and small intestines respectively. Other test that may be conducted includes computed tomography of the abdominal area, endoscopy, enteroscopy and magnetic resonance imaging.

Treatment

To treat Crohn's disease, a lot of options are available, these may include the use of drugs, surgery, nutritional supplements or a combination of all the above in severe…

Sources Used in Documents:

References

Barratt, S, Leeds, J.Robinson, K.,Lobo, A. McAlindon, M.Sanders, D. (2011)Prodromal Irritable Bowel Syndrome May Be Responsible for Delays in Diagnosis in Patients Presenting with Unrecognized Crohn's Disease and Celiac Disease, but Not Ulcerative Colitis. Digestive Diseases & Sciences; Nov2011, Vol. 56 Issue 11, p3270-3275.

Leaner, A (2012).Aluminum as an adjuvant in Crohn's disease induction. Lupus; Feb2012, Vol. 21 Issue 2, p231-238.

Marks DJ, Segal AW. (January 2008). "Innate immunity in inflammatory bowel disease: a disease hypothesis." J. Pathol.214 (2): 260 -- 6. doi:10.1002/path.2291. PMC 2635948.PMID 18161747.

National Digestive Diseases Information Clearinghouse .(2006).Crohn's Disease
http://digestive.niddk.nih.gov/ddiseases/pubs/crohns/Crohns.pdf
http://www.fda.gov/downloads/ForConsumers/ConsumerUpdates/ucm107364.pdf


Cite this Document:

"Crohn's Disease" (2012, February 16) Retrieved December 5, 2021, from
https://www.paperdue.com/essay/crohn-disease-54286

"Crohn's Disease" 16 February 2012. Web.5 December. 2021. <
https://www.paperdue.com/essay/crohn-disease-54286>

"Crohn's Disease", 16 February 2012, Accessed.5 December. 2021,
https://www.paperdue.com/essay/crohn-disease-54286

Related Documents
Crohn's Disease an Overview of the Most
Words: 788 Length: 3 Pages Topic: Disease Paper #: 84103375

Crohn's Disease An Overview of the Most Pertinent Facts Relating to Crohn's Disease Crohn's Disease Affects the Digestive System (Journey with Crohn's, N.d.) Crohn's disease is a serious condition that afflicts roughly half a million people in North America alone. The disease affects the bowels of a patient, anywhere between the mouth all the way to the anus, and has a wide range of symptoms associated with it. Some of the symptoms include

Crohn's Disease
Words: 1100 Length: 4 Pages Topic: Disease Paper #: 59273880

Crohn's Cronh's Disease and Ulcerative Colitis Background Crohn's disease (CD) and ulcerative colitis are the major forms of chronic inflammatory bowel diseases (IBD) in the western world, and occur in young adults with an estimated prevalence of more than one per thousand inhabitants (Hugot, et al., 1996). These diseases can affect any portion of the gastrointestinal system all the way from the mouth to the anus and are associated with many other

Crohn's Disease in Canada
Words: 892 Length: 2 Pages Topic: Disease Paper #: 87092618

Crohn's Disease In Canada CROHN'S DISEASE Crohn's disease has another name of regional enteritis. It is an intestinal disease which is inflammatory and can affect different parts of the gastrointestinal tract which can be from mouth to the anus having array of symptoms. Its effects are pain in the abdomen, diarrhea which when is at the worst inflammation it can contain blood in the diarrhea, vomiting and all these may result to

Crohn's Disease: Promising New Findings
Words: 861 Length: 2 Pages Topic: Disease Paper #: 12220248

The study supports the findings of the recent NF-kB research given that infliximab neutralizes an inflammation-causing protein called tumor necrosis factor alpha. This protein regulates "a common inflammation pathway that just happens to be important in Crohn's disease," suggesting that a specific, targeted molecular approach to treatment may be more helpful for Crohn's patients than steroids (Seppa 2008) Future drugs, however, could directly address the problems regarding NF-kB, rather than

Inflammatory Bowel Disease: Immunological, Demographical, and Genetic...
Words: 1906 Length: 6 Pages Topic: Disease Paper #: 22165283

Inflammatory Bowel Disease: Immunological, Demographical, and Genetic Findings Inflammatory bowel disease (IBD) affects the colon and the small intestine. Though there are many subtypes of IBD, the most common and well-known are Crowns disease and ulcerative colitis (WebMD.com, 2011). Crohn's disease causes symptoms such as abdominal pains, diarrhea, vomit, weight loss, as well as many non-digestive system related pains (WebMD.com, 2011). Ulcerative colitis is quite similar to Crohn's disease due to noticeable

Ileitis, Enteritis, or Regional Enteritis, Crohn's Disease
Words: 1081 Length: 3 Pages Topic: Disease Paper #: 99081199

ileitis, enteritis, or regional enteritis, Crohn's disease is a relapsing, inflammatory bowel disease that affects the ileum (lower part of the small intestine), which becomes inflamed and swells deep into its lining ("Crohn's Disease," 2006; Nachimuthi, 2005; Baumgart & Sandborn, 2007). It can affect the entire gastrointestinal tract -- from the mouth to the anus -- but is typically found in the lower part of the intestine ("Crohn's Disease,"