DNA Is The Abbreviation For Deoxyribonucleic Acid, Term Paper

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DNA is the abbreviation for deoxyribonucleic acid, which is a complex giant molecule that contains, in chemically coded form, the information needed for a cell to make proteins (DNA Pp). DNA is a "ladderlike double-stranded nucleic acid that forms the basis of genetic inheritance in all organisms, except for a few viruses that have only RNA" (DNA Pp). DNA is organized into chromosomes, and, in organisms other than bacteria, is found only in the cell nucleus (DNA Pp). It is made up of two chains of nucleotide subunits, with each nucleotide containing a purine, (adenine or guanine), or pyrimidine (cytosine or thymine) base (DNA Pp). These bases link up with one another, the adenine links with thymine, and cytosine with guanine, to form base pairs that "connect the two strands of the DNA molecule like the rungs of a twisted ladder" (DNA Pp). The base sequence is preserved from generation to generation by the specific way in which the pairs form, thus, hereditary information is stored as a specific sequence of bases (DNA Pp). A set of three bases, called a codon, acts as a blueprint for the manufacture of a particular amino acid, the subunit of a protein molecule (DNA Pp). The meaning of each of the codons in the genetic code has been worked out by molecular geneticists, thus, codons are identified by the initial letters of the constituent bases, for example, "the base sequence of codon CAG is cytosine-adenine-guanine" (DNA Pp). There are four different bases, meaning that there must be "4 & #215; 4 & #215; 4 = 64 different codons"...

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Generally, proteins are made up of only twenty different amino acids, therefore many amino acids have more than one codon, for example, "GGT, GGC, GGA and GGG all code for the same amino acid, glycine" (DNA Pp).
The information encoded by the codons is transcribed by messenger RNA and is then translated into amino acids in the ribosomes and cytoplasm (DNA Pp). Because the sequence of codons determines the exact order in which amino acids are linked during manufacture, it also determines the kind of protein that is to be produced (DNA Pp). Since proteins are the main structural molecules of living matter and, as enzymes, regulate all aspects of metabolism, it can be "seen that the genetic code is effectively responsible for building and controlling the whole organism" (DNA Pp). It is possible to determine the sequence of bases along the length of DNA by cutting the molecule into small portions, using restriction enzymes, "this technique can also be sued for transferring specific sequences of DNA from one organism to another" (DNA Pp).

The oldest sequenced DNA to be found belongs to a nemonychid weevil that was trapped in amber from the Cretaceous period and estimated to be 120-135 million years old (DNA Pp). In 1994, American researchers extracted DNA from human hair that was 10,000 years old and that same year, dinosaur DNA was extracted from unfossilized dinosaur bones found in a coal mine in Utah (DAN Pp).

In 1991 hikers in the Italian Alps found a frozen body of a man who was later…

Sources Used in Documents:

Work Cited

"DNA." The Hutchinson Dictionary of Science. Helicon Publishing Ltd. 1998; Pp.

Poinar Jr., George. "Ancient DNA." American Scientist; 9/1/1999; Pp.

Sancar, Aziz. "DNA repair in humans." Annual Review of Genetics; 1/1/1995; Pp.

Hsieh, Peggy. "DNA mismatch repair: molecular mechanisms and biological function." Annual Review of Microbiology; 1/1/2003; Pp.


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