Genomic Medicine Essay

Length: 2 pages Sources: 1 Subject: Genetics Type: Essay Paper: #65995336 Related Topics: Anemia, Medicine, Genetic Testing, Biotechnology
Excerpt from Essay :

¶ … Human Genome Project

Launched in 1990 as a collaborative initiative between the National Institutes of Health and the U.S. Department of Energy, the Human Genome Project completed its goal ahead of time despite the enormous challenges that were involved (Greene, 2006). The goals of the Human Genome Project included developing comprehensive genetic and physical maps of the human genome in order to determine the complete nucleotide sequence of the three billion base pairs that make up the human DNA and to identify the estimated 100,000 genes that are contained within the human genome (Greene, 2006). To determine the importance and implications of the HGP, this paper reviews the relevant literature, followed by a summary of the research and salient findings concerning this initiative in the conclusion.

Review and Discussion

1)

How will research in the Human Genome Project further medical research? What disorders are most likely to benefit from the project?

To date, the Human Genome Project has identified more than 1,800 disease genes which has facilitated research into the etiology of genetic diseases...

...

The Project has enabled researchers to identify the genes that are suspected of causing diseases far more rapidly than in the past, and more than 2,000 tests for various human conditions have already been developed. According to the Project's sponsors, "These tests enable patients to learn their genetic risks for disease and also help healthcare professionals to diagnose disease" (Human Genome Project, 2015, para. 3). Moreover, there are currently clinical trials underway for at least 350 biotechnology-based products using data developed by the Human Genome Project (Human Genome Project, 2015). Although a wide array of disorders are likely to benefit from the Project, the dramatic reductions in the costs of genetic testing have already identified the causes of diseases such as Kabuki and Miller syndromes, conditions that are rare (Human Genome Project, 2015).

2)

How would you react to receiving a genetic test that states that you had an 85% chance of developing a debilitating or fatal condition? Be specific about the condition and how you would handle it.

Today, sickle cell disease is currently the most prevalent genetic-based hematological disorder in the world and the condition can affect anyone (Burnes & Antle, 2008). Approximately 2 million Americans currently suffer from this disorder (Sickle cell anemia, 2014). Assuming this writer received a genetic test that indicated an 85% chance of…

Sources Used in Documents:

References

Burnes, D.P. & Antle, B.J. (2008, August). Mothers raising children with sickle cell disease at the intersection of race, gender, and illness stigma. Health and Social Work, 33(3), 211-

Greene, L.A. (2006, January). Human Genome Project information. Environmental Health

Perspectives, 109(1), 19.

Human Genome Project. (2015). National Portfolio Online Reporting Tools. Retrieved from http://report.nih.gov/NIHfactsheets/ViewFactSheet.aspx?csid=45&key=H#H.
Sickle cell anemia. (2014). National Heart, Lung, and Blood Institute. Retrieved from http://


Cite this Document:

"Genomic Medicine" (2015, January 08) Retrieved January 16, 2022, from
https://www.paperdue.com/essay/genomic-medicine-2148390

"Genomic Medicine" 08 January 2015. Web.16 January. 2022. <
https://www.paperdue.com/essay/genomic-medicine-2148390>

"Genomic Medicine", 08 January 2015, Accessed.16 January. 2022,
https://www.paperdue.com/essay/genomic-medicine-2148390

Related Documents
Companion Diagnostics Translational Medicines
Words: 4711 Length: 15 Pages Topic: Medicine Paper #: 9971327

Translational medicine is a new discipline, which covers studies on basic science, on human investigations, non-human investigations, and translational research (Mankoff et al. 2004). Basic science studies address the biological effects of medicines on human beings. Studies on humans discover the biology of disease and serve as foundation for developing therapies. Non-human or non-clinical studies advance therapies for clinical use or use in human disease. And translational research refers to

Personalized Medicine
Words: 624 Length: 2 Pages Topic: Medicine Paper #: 51755248

Personalized medicine uses advanced and evolving understanding of genetics to make medical interventions safer and more effective. With genetic science, doctors are able to target medications and procedures for patients directly, creating an unprecedented "personalized" approach to medicine. Traditional allopathic medicine relies on empirical research that generalizes results for an entire population. This has led to problems related to patient side effects, some of which are serious. As the National

Personalize Medicine
Words: 955 Length: 3 Pages Topic: Disease Paper #: 30316537

Personalized medicine as a field started developing in response to the recognition that every person is different in terms not only of genetic and genomic information, but also in terms of his or her clinical and environmental information. The fact that all these areas are different for each person means that each person would respond to illness in a different way, including the onset and duration of the condition. For

Transplant Medicine the Major Histocompatibility Complex MHC
Words: 1052 Length: 3 Pages Topic: Disease Paper #: 90177750

Transplant Medicine The Major Histocompatibility Complex (MHC) contains over 128 functional genes. This is the densest part of the human genome and is responsible for most autoimmune diseases. This region also determines vaccine responsiveness, adverse drug reactions, disease progression and transplant rejection. The MHC genes are multigenic with a high degree of allelic polymorphism. There are over 7,500 different alleles and over 5,458 expressed MHC antigens currently known. (DeFranco, Locksley &

Cystic Fibrosis Clinical Medicine and
Words: 952 Length: 3 Pages Topic: Disease Paper #: 74138071

This in turn leads to cytoplasmic water retention and the buildup of viscous mucus in the lungs and other areas of the body. This is particularly problematic for the lungs because the thick mucus impairs clearance of invasive particles and infectious agents to maintain a sterile environment. Microbial contamination of airway surfaces triggers an inflammatory response, including a massive invasion by neutrophils (Rodrigues et al., 2008). As the neutrophils react

Genome Project on Drug Design
Words: 1163 Length: 4 Pages Topic: Medicine Paper #: 47141523

IV. TESTING ON HUMANS The only thing that is lacking at this point according to all reports is for testing on humans to be completed. The Time Asia articles states: "The last step for the ace-2 inhibitor, as for any drug, is human clinical trials. Because the U.S. Food and Drug Administration requires such rigorous testing, this is by far the most expensive part of drug development. So for human trials