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Human Genome Project
One of the primary concerns of the biological sciences today is human health. The more information is made known about the human body, the more curative and preventive steps can be taken to ensure the longevity and health of the human body. This is one of the ends of the Human Genome Project (HGP), which was concluded in 2003. The project ran for 13 years and was coordinated by the U.S. Department of Energy and the National Institutes of Health.
US Department of Energy (2012). In addition, the Wellcome Trust in the U.K. became amajor partner in this effort, while contributions were also received from Japan, France, Germany, China, and other countries. The HGP's main goals were to gather information and apply the findings to human health. It should, however, also be noted that the project has several ethical and social implications.
Several main goals were identified…… [Read More]
uman Genome Project (GP) was designed to provided detailed and complete information about the genes in human DNA. Not funded by any private corporation, the GP will generate information that can be used by a wide variety of agencies and companies in the 21st century and beyond (Guyer & Collins, 1995). With this information, scientists can greatly improve how they perform human research, and the medical implications may have few limits.
When completed, scientists and researchers will have a map of human the 50,000-100,000 genes contained in human DNA. In addition, since some research with genetic implications for humans is done with other organisms, those organisms will also be mapped (McDaniel, 2005). The GP currently stands as the single most dramatic sphere of biological research, and holds the power to change studies in biology and psychology as well as medicine. Currently in its final stage, parts of the human DNA…… [Read More]
Since the antigens are closely linked to race and ethnicity, it is much easier to find a biological match among people with similar ethnic and racial backgrounds than it is among any two randomly selected individuals. On the basis of tissue matching, organs from blacks will almost always go to blacks and organs from whites will almost always go to whites. Blacks, however, have a much higher incidence of kidney failure than whites. But since whites significantly outnumber blacks in the American population, there are still large numbers of whites waiting for organs. There are so many, in fact, that nearly every white donor is matched to a white recipient. Blacks and other minorities must rely on a much smaller pool of kidneys. The situation for potential black kidney transplant recipients is made even worse by the fact that blacks have a lower rate of cadaver organ donation than do…… [Read More]
The ethical concerns about the ability to obtain this information revolve around the possibility of discrimination against people who have less than superior gene pools and that those people will be shunned from society, or worse yet, rounded up and locked up before they have ever done anything wrong.
In addition there is also the concern that the wealthy will be able to genetically order perfect children with the highest IQ's the healthiest DNA and the best looks, while those who are not wealthy will have children the old fashioned way and there will be an eventual class distinction between the children who have been genetically ordered and those who are a toss of the dice.
The other ethical issue involves a perceived right to privacy. The recent health care privacy act has worked to further protect a person's right to decide who has information about him and why…… [Read More]
ability to study of Human Genome is an important scientific discovery that posed major threats to the great ideals of human dignity, privacy and confidentially of one's medical history when it first made headlines in 1998. To fully exploit the scope of this discovery, Human Genome Project was launched that again had few supporters and numerous opponents. The general public, not aware of the deeper scientific reasons behind launching of this project, staunchly opposed it and yet there were some big names in the field who not only backed the program but also tried to raise awareness regarding its numerous benefits. One such person is James D. Watson, whose impressive credentials and long list of services in the field put him in an enviable position to carry put the task. His essay "The Human Genome Project: A Personal View" was one of the first few steps he took to gain…… [Read More]
IV. TESTING ON HUMANS
The only thing that is lacking at this point according to all reports is for testing on humans to be completed. The Time Asia articles states: "The last step for the ace-2 inhibitor, as for any drug, is human clinical trials. ecause the U.S. Food and Drug Administration requires such rigorous testing, this is by far the most expensive part of drug development. So for human trials in some cases, Millennium has formed partnerships with large pharmaceutical companies that have the necessary resources and will share in any eventual profits." (2001)
SUMMARY & CONCLUSION
According to the work entitled: "rave New Pharmacy" published in Time Asia (2001) "When the human genome was sequenced...scientists finally gained access to the full text of God's reference manual; the 3 billion biochemical 'letters' that spell out our tens of thousands of genes. These genes, strung out along the 46 chromosomes…… [Read More]
Genomes and Comparative Genomics
Over the last decade we have achieved rapid strides in the field of genetic engineering. The study of molecular biology has been fairly advanced mainly aided by the unprecedented growth in information technology. Today bio-informatics has opened new vitas for us and we are already progressing in investigating and in the comparative study of genomes. This has shed new light up on our knowledge of the evolutionary process and the important concepts such as protein folding and selective expression, which have so far eluded our understanding, are beginning to unfold. Let us have a brief overlook of the subject.
The Role of DNA
One of the greatest achievements of the twentieth century has been the unraveling of the mysteries behind the DNA and the mechanism of protein synthesis. Genes are the fundamental units of biological inheritance and are made up of Deoxyribonucleic acid (DNA). Genes are…… [Read More]
(iii) in the United States, Brazil, Germany and France, humans have been receiving their own stem cells to re-grow heart muscle in the unforeseen incident of heart attack or injury. This was found to be successful in majority of the cases. (iv) in one more incident, the vision of 23 patients was restored after limbal adult stem cell transplants. This line of therapeutic care has assisted a lot of people who have been suffering from blindness for years together that includes the sufferers of mustard gas attacks in Iraqi. (Life Issues Institute, 2006) v) Crohn's disease patients have in fact been treated with stem cells evolved from their own blood. (vi) Among the 90% of the 19 patients having several autoimmune disorders like systemic lupus has been on the path to recovery following treatment with their own blood stem cells. (vii) a research of Parkinson's disease displayed an average improvement…… [Read More]
Another landmark case involved global giant British Petroleum (BP) in the largest fine in OSHA history. The case involved the explosion at a BP refinery in Texas that killed 15 people and injured 170 others. An OSHA press release notes, "This citation and penalty - nearly double the next largest fine in OSHA history - sends a strong message to all employers about the need to protect workers and to make health and safety a core value,' Solicitor of Labor Howard M. adzely stated" (Groover, 2005). The implications for human resource implementation are again clear. Without the proper training, the individuals in the plant did not operate some of the processing equipment effectively, and pressure built up in the unit that exploded. Part of the settlement required BP to "hire an expert to assess and report on communication within and between management, supervisors, and authorized employee representatives and non-management employees…… [Read More]
Human Genome, Stem Cells, & Reparations
Stems Cells are the source of all body tissues. Growth and development of the human body arises from the stem cell and is maintained by it. Although all cells can divide or copy themselves, stem cells are unique because they can replicate and create all other types of cells. This ability of the stem cell to develop into any of the 220 cell types that make up the human body makes it a powerful tool for biological research and medicine. Scientists believe that stem cell research has the potential of leading to previously incurable diseases.
How are Stem Cells Formed?
When a sperm cell fertilizes an egg, a zygote (fertilized egg) is formed. The zygote divides itself almost immediately to form stem cells. These unspecialized stem cells have the ability to replicate (to form other stem cells) and to make all other specialized cells…… [Read More]
Project Management, Sustainability and Whole Lifecycle Thinking
Module 5 Case -- the esearch Essay
For nearly the entirety of human civilization, thinkers, philosophers, and indeed most human beings, have struggled to determine the most elusive aspects of identity. Balancing the essence of human nature against the effects of environmental influence eventually formed the foundation of the ongoing debate concerning nature vs. nurture. With the advent of remarkable technology capable of mapping the human genome, most people in today's modern world believe that their genetic makeup holds the key to their future health, personality traits, intelligence quotient, and even their fears. The unique confluence of factors that combine to form the personality traits, behavioral patterns, and ethical boundaries exhibited by every human being has spawned two distinctly divergent theories, with the majority of people advocating the influence of genetics over external environment. Proponents of the "nature" point-of-view assert a person's physical…… [Read More]
Human Genome Project
Launched in 1990 as a collaborative initiative between the National Institutes of Health and the U.S. Department of Energy, the Human Genome Project completed its goal ahead of time despite the enormous challenges that were involved (Greene, 2006). The goals of the Human Genome Project included developing comprehensive genetic and physical maps of the human genome in order to determine the complete nucleotide sequence of the three billion base pairs that make up the human DNA and to identify the estimated 100,000 genes that are contained within the human genome (Greene, 2006). To determine the importance and implications of the HGP, this paper reviews the relevant literature, followed by a summary of the research and salient findings concerning this initiative in the conclusion.
eview and Discussion
How will research in the Human Genome Project further medical research? What disorders are most likely to benefit from the…… [Read More]
However, the use of this technology has also introduced a whole host of ethical and health issues. This is important, because how these issue are wrestled with in the future, will determine the way this technology will be applied to daily life.
A bibliography that includes all references cited in the report and a 1-2 sentence summary of what information was gained from each reference.
20 Questions on Genetically Modified Foods. (2010). HO. Retrieved from: http://www.who.int/foodsafety/publications/biotech/20questions/en/
This source identified specific ethical and health issues that are affecting the use of genetic engineering. It was useful in recognizing specific factors and issues that could be affecting the way genetic engineering is impacting daily life.
The Search for the Structure of DNA. (2010). Online Ethics. Retrieved from: http://www.onlineethics.org/Education/precollege/scienceclass/sectone/cs4.aspx
This source was useful in providing background as to when DNA was discovered and what compounds were looked at before its discovery.
Ejelonu, A.…… [Read More]
The clinical trial team includes doctors, nurses, social workers, data entry technicians and other health care professionals (NWHRC 2005). They review a participant's health history and current medical intakes before the trial begins. They impart adequate information and instructions about the clinical trial, monitor each participant in the conduct of the trial and may contact the participant after the conduct of the trial.
Clinical trials or researches may also be open-label, placebo-controlled, double-blinded or randomized. They consist of four phases. Phase I establishes the maximum safe dosage; Phase II, its effectiveness; Phase III, its use on a broad population; and Phase IV, post-FDA insights on the effects of its long-term use (NWHRC).
From 1999 to 2000 alone, the Food and Drug Administration approved 73 new medications (NWHRC 2005). These included drugs for HIV, cancer, heart attack and Alzheimer's disease. As of 2000, Medicare covers many of the costs involved in…… [Read More]
Personalized genomics and personalized medicine refers to a collection of technologies and techniques designed to custom design pharmaceutical treatments according to the patient's genome sequence. The starting point for personalized medicine, which has also been called "stratified medicine" or "precision medicine" is the completion of the Human Genome Project (NHMC, 2014). The Human Genome Project has permitted unprecedented access to genetic information and the implications the information has on human health factors.
A genome is the entire collection of genes, about 23,000 different ones, embedded in each cell of the body (The Jackson Laboratory, 2014). According to Snyder, Du & Gerstein (2010), determining a genome sequence involves "identifying single-nucleotide polymorphisms [SNPs] and structural variations [SVs], assembling new sequences, and phasing haplotypes," (p. 423). Although only two percent of the human genome is actually comprised of genes themselves, the human genome "influences how we look, our genetic…… [Read More]
technology has revolutionized society: communication, transportation, commerce, and especially medicine. . Ironically, for centuries and still in Oriental Medicine, healthcare was and is tailored to the individual. Even the Greek Physician Hippocrates wrote that he prescribed sweet elixirs to some and astringents to others depending on their individual condition (Pray, 2008). 21st century medicine, though, is more about an individual person's genetic code, and is made possible by advances in genetic technology and engineering. This is partially due to the Human Genome Project, a massive program completed in 2003 that focused on the identification of the individual genes that make up human DNA with the overall hope that it would initiate genomic medicine -- healthcare delivered based on the individual's medical history and genetic profile (About the Human Genome Project, 2011). Traditionally, medicine diagnoses human illnesses based on quantitative and qualitative signs and symptoms. With the advent of genetic technology,…… [Read More]
Medical Research Funding - Government vs. Private
Most research funding comes from two major sources: corporations and government. Some small amounts of scientific research are carried out by charitable foundations, especially in relation to developing cures for chronic diseases.
Government funding for medical research amounts to approximately 36% in the U.S. he government funding proportion in certain industries is higher, and it dominates research in social science and humanities. Similarly, with some exceptions government provides the bulk of the funds for basic scientific research. In commercial research and development, all but the most research-oriented corporations focus more heavily on near-term commercialization possibilities rather than ideas or technologies.
Government-funded research can either be carried out by the government itself, or through grants to academic and other researchers otside the government. Critics of basic research are concerned that research funding for the sake of knowledge itself does not contribute to a great…… [Read More]
The rapidly increasing demand of healthcare needs and preventions methods along with newer forms of diseases being discovered each day, extensive investments have been made in researching the field of medicine to revolutionize the future of medicine. Medical practitioners are looking up to a promising future proposed by the studies being carried out in the fields of genetics. This has open doors for a new and one of its kind form of medicine, namely 'Personalized Medicine.' As the name suggests, this type of medicine is patient specific and involves carrying out diagnosis and treatment plans that is customised to suit individual needs.
With the increase in demands of health care needs and with the discoveries of newer and more mysterious diseases, researches are being carried out at rapid rate to discover newer methods of health care needs. These health care services includes a wide variety of medication practices…… [Read More]
living things are characterized by the following seven characteristics namely mobility, respiration, excretion, sensitivity or response to external stimulus, growth, feeding, and reproduction. Though there may be variations between animal and plant kingdom (ex, plants take in carbon dioxide and prepare their own food), these characteristics are commonly observed among all living things.
iology is a very broad field that encompasses the study of characteristics of living things. It includes botany, zoology and all other sub-disciplines that range from microbiology to evolution and ecology.
Evolution is the branch of biology that deals with the study of natural development of living organisms and the changes in them over time. Evolution refers to the heritable changes that occur in a population over a period of time. All the diversity that is observed currently in plant and animal kingdom can be ascribed to evolution over a long period of time.
Atoms are the…… [Read More]
During the gene decoding process the double stranded DNA splits up to reveal a single strand from which the base sequence of the gene is copied onto a single stranded nucleic acid known as the messenger ribonucleic acid or mRNA. This implies that we have an exact copy of the gene base in the mRNA except that Urasil (U) replaces the T. base and deoxyribose is replaced by ribose. Translation on the other hand is the actual process of protein synthesis from the mRNA strands. Ribosomes work with the mRNA for protein synthesis within the cells. [the State University of New York]
4) Mutation, Gene Migration, Genetic Drift, Non-random Mating and Natural Selection are the five processes that can affect the frequency of genes in a population. [CMGS]
5) Kindom Protista is considered to be the ancestor of all eukaryotic kingdoms and includes algae, plant like, animal like and fungus…… [Read More]
Fiction of ace
ace: The cultural power of the fiction of race
A recent PBS documentary was titled ace: The power of an illusion. This underlines what constitutes race -- race is a fiction, created by the faulty observational perceptions of human beings, and the history of human culture. ace is not a scientific reality. Because we can see color (and hair texture, facial shapes, and other characteristics) we perceive something we call race. But our scientific knowledge tells us that race does not exist. This is not to deny that race is a very powerful fiction that has influenced human history. The idea of racial categories proved to be deadly and destructive to the lives and the cultures of indigenous peoples. It was used to validate slavery, genocide, colonialism, and exploitation. But race is not 'real,' any more than the idea of 'carrying the white man's burden' was…… [Read More]
The employee is faced with ethical requirements throughout their workday that must be met with knowledge and a trained attitude. Workplace ethics is one of the most crucial elements whether the person involved in an ethical dilemma is a high-level manager or an entry-level employee. An ethical stance is important because it is what guides the interactions that the employees will have with each other, their management, and the customers that patronize their products. It is also important that the business leaders follow an internal and external ethical stance so that the culture generated within the company is one that promotes positive ethical practices. This paper begins by talking about the way that the business leaders view the external world of ethics through accounting practices and how they deal with other companies. The discussion then moves inside the company and how the management treats its employees. Employee to employee…… [Read More]
Genetically Modified Foods: ational for Topic Selection
Genetically modified foods are frequently in the mainstream media, making them a highly relevant topic of discussion in the areas of genetic science and gene technologies. As with most technologies and techniques related to genetic science, genetically modified foods are controversial and thus politically charged issues. It is important to be armed with facts before forming an opinion about whether or not genetically modified foods are acceptable, feasible, or ethical.
Genetically modified foods refers to organic foodstuffs -- plants and animals -- "whose genetic material (DNA) has been modified in a way that does not occur naturally," (World Health Organization, 2013). However, genetically modified organisms (GMOs) can also include medicines and vaccines (United States Department of Energy: Office of Science, 2013). The primary process used to modify the genes of organisms is called recombitant DNA technology; as the term suggests, recombitant…… [Read More]
Nature of Cognition
Ever since Simon and inet developed the first intelligence test in 1905, the field of psychology has maintained a strong interest in the nature of intelligence. How do we think? Why are some people better problem solvers than others? What is cognition, the ability to think about our environment? Why are some people consistently more able to use their brains to think, to remember, and to problem-solve than others?
The first IQ tests were devised to determine which children were mentally retarded. These children were pulled away from mainstream education. However, the tests did an effective job of predicting school success for all students, and their use was broadened (Sternberg, 1999). Multiple tests were developed to measure cognition, which might be defined as the ability to think abstractly. Markman (2001) described it in this way:
Cognition depends on the ability to imagine or represent objects and events…… [Read More]
Genomics and Implications for the Future
The Human Genome Project has completed its monumental mapping of the genetic sequence in human DNA, and the field of genomics is taking advantage of these initiatives and innovations in technology to pursue scientific inquiries that could not have been imagined just a few years ago. More importantly, perhaps, new applications are being discovered based on the growing body of scientific evidence being developed by this emerging science. To determine what genomics is and how it is being used today and may be used in the future, this paper provides an overview of the biochemistry involved in the study of genomics, followed by an analysis of current and future trends in this field. A summary of the research will be provided in the conclusion.
Review and Discussion
Background and Overview.
Today, genetic-engineering techniques are increasingly being applied to a growing number of life forms,…… [Read More]
The development of a bio-economy capable of supplying the world's energy demand is where the synthetic biologists wish to take this the next step. Additionally, biologists are able to develop a sort of biological acolyte from the principles of synthetic biology, involving synthesizing DNA in combination with the raw building blocks of genetics. A new platform for different biological life form is essentially, what these biologists have discovered.
According to commission chairwoman, and the president of the University of Pennsylvania, Amy Gutmann, "Here's something significant in science, but there's no cause for fear and dread about what is going to happen immediately next." The commission report recommended greater ethical constraint and greater collaboration. Amy Gutmann, further states that ethics training be mandatory for all researchers in the field.
Opponents of the report include Brent Erickson, an executive in the biotech industry. According to the New York Times, Mr. Erickson called…… [Read More]
" (Burczynski & Dorner, 187)
Another avenue of screening employs developing microscopic patterning technology called DNA microarray technologies in order to view certain characteristics of an individual's genetic makeup and health scenario. As Rushmore & Kong (2002) report, "advances in DNA microarray technologies and mammalian genome sequencing will soon allow quantitative assessment of expression profiles of all genes in the selected tissues." (Rushmore & Kong, 481)
This is particularly important because it represents opportunities in an area where most pharmacogenomics professionals contend the field must be expanded. At present, the largest focus in terms of application has been identifying single polymorphous cells for evaluation with respect to certain drug response likelihoods and tendencies. Naturally, the human genome is an incredibly complex chemical equation rendered by a set of permutations that is, for all intents and purposes, infinite. Therefore, the degree to which pharmacogenomics actually succeeds at improving treatment outcomes will…… [Read More]
(We've never had it so good - and it's all thanks to science) Thus the question of genes is an effect on certain humans and their behavior; in short their physical and behavioral traits. That does not change the view of society on what a well nurtured human is.
Thus we still expect "other people" in society to be upright, polite, incorruptible, generous, are honest, hard working, well-informed, broadminded, who are conscious about society, sensitive to environment, non-violent and self-restraint. In short, those are the objectives of good nurturing, but does it happen all the time? Even in the Old Testament we had the tale of Cane and Abel. Society involves both nature and nurture.
Bad Gene Ups Prostate Cancer isk in Black Men. 9 July, 2003. etrieved at http://www.hon.ch/News/HSN/513973.html. Accessed on 10 August, 2005
Did the march of progress bring Aids to Africa? Sydney Morning Herald. 15…… [Read More]
Candidate Genes for Schizophrenia
Their Impact on Neuro-development
Search Improvement over Published Methodology
rief Introduction -- Schizophrenia is a mental disorder, which is characterized by delusions, lack of drive and interest, changed or unusual emotional reactions and generally disorganized behavior (Kirov et al. 2012). Some signs may begin from childhood but main features become apparent in the late teens and early adulthood. Outcomes and treatment are varied but relapses are frequent. Remissions are also often only partial along with significantly reduced social and occupation involvement. Persons with this disorder are among the most vulnerable, ostracized, and thus disadvantaged in society. A recent meta-analysis reported that about 15.2 out of every 100,000 persons are afflicted with it (Kirov et al.).
Genetic epidemiological studies theorize that varied susceptibility to schizophrenia appears to be strongly genetic (Kirov et al. 2012). These studies have identified many potentials links between genes and chromosomal abnormalities. Increasing…… [Read More]
Medical Advancements in Medicine and Health
Write a three-page paper on what you believe is the most significant medical advancement (s) in medicine and health and support your argument.
Genetic engineering is one of the most significant medical advancements of the century and will have a major impact on medicine, health, politics and church and state relationships.
Genetic engineering. A controversial issue or a blessing in disguise? The Human Genome Project (HGP), sponsored in the United tates has created the field of genomics --understanding genetic material on a large scale.
But what actually is genetic engineering? Genetic engineering in theory, allows cells to grow in a petri dish, with the end result of creating the type of genetic alteration you want. Imagine the medical ramifications of being able to genetically create the characteristics we want in a species. Think of the benefits to mankind and the enhancements that would be…… [Read More]
Adolescent Behavioral Traits
The 'era of the genome' officially began on April 12, 2003 when the entire human DNA sequence had been declared completed (Gannet, 2008). Although there was considerable resistance to the project from the beginning, the subsequent boom in medical and genetic advances are hard to ignore. For example, BAE and colleagues (2013) recently published a genome-wide association study that searched for and found specific DNA sequences significantly associated with agreeableness and long life spans. This study would not have been possible in the pre-genome era.
Despite these remarkable advances, however, genetic research has been going on for decades in the behavioral sciences, thereby laying a foundation upon which more recent genome era discoveries can be based. To better understand this foundation, a selection of studies examining the gene-by-environment influences on child and adolescent behavior will be reviewed and discussed in this essay.
Genetic Determination of…… [Read More]
detection and intervention in childhood mental health help prevent mental health problems in adult life?
Disregarding the mental well-being requirements of children is an intolerable violation of our basic undertaking to protect their well-being. Unfavorable mental disposition amidst our children is a less acknowledged difficulty that influences their literary, societal, and emotional enhancement. Mental well-being is a wide attribute to be analyzed. The mental well-being requirements of children and youth demand introspection. There is prevalent refuting that mental well-being is comprehensive of the influence on the children -- amidst all age distinct ions, variety of cultural sections, and all income sections. Such miscomprehensions are recurring, and involvement and care are unlikely to be found. Many people have the belief that children having mental well-being difficulties are just under the impact of a particular passing cloud. (Promoting Access for Children to Mental Health Screens and Assessments in Medicaid and the Children's…… [Read More]
standing and intense debate as to whether human personality is determined or influenced biologically or psychologically. Those in the pro-biological (or pro-nature) side contend that a person's genes have a stronger or final say about a person's acts and destiny, while those in the psychological (or pro-nurture) side say it is the way the person is/was raised as a child and his peer interaction that determine the personality system that will evolve. Does the human personality derive from nature or from nurture? Is his learning achievement, social or moral formation, habits and viewpoints ingrained in his genes or established by the way he is brought up?
The pro-nature side holds that learning or knowledge acquisition, in particular, is in itself a kind of genetic information that is pre-determined by natural selection (Csongradi 2004). Some of the knowledge a person gains may come from interactions or functionally, but what is genetically…… [Read More]
Translational medicine is a new discipline, which covers studies on basic science, on human investigations, non-human investigations, and translational research (Mankoff et al. 2004). asic science studies address the biological effects of medicines on human beings. Studies on humans discover the biology of disease and serve as foundation for developing therapies. Non-human or non-clinical studies advance therapies for clinical use or use in human disease. And translational research refers to appropriate product development for clinical use. Translational research looks into the identity, purity and potency of a drug product during early clinical trial (Mankoff et al.). Translating the knowledge derived from basic sciences into clinical research and treatments is the task of translational medicine (Nagappa 2006). There is a groaning need for this type of research on account of voluminous information in the information age. Using this information is the challenge encountered by scientists and healthcare providers everywhere in the…… [Read More]
ith the emergence of new technologies and procedures
has occurred the emergence of new experts. According to Rose, "around these
experts of the soma cluster a whole variety of new pastoral experts-genetic
counselors are perhaps the best exemplars-whose role is to advise and guide
to care and support, individuals and families as they negotiate their way
through the personal, medical and ethical dilemmas that they face. And,
perhaps, most remarkable has been the rise of a novel expertise of
'bioethics.'" (Rose, 6)
This is the subject which commands perhaps the greatest importance in
Rose's text, striking relevance into every other aspect of the debate by
suggesting that this essentially subjective lens has come to dominate a
field traditionally ruled by empiricism. To this point, optimization has
been distinctly impacted by this false or self-proclaimed sense of somatic
Indeed, in his dealing throughout the text with this issue of
optimization,…… [Read More]
Kringlen also published more extensive case records for his monozygotic twins than any other researcher had done (pp. 7-8)."
The information gained by these studies was significant. One, in particular, conducted by William Pollin and his colleagues set out to disprove the biological or genetic factors, and to establish the basis for.".. psychodynamic, interpersonal phenomena that might have some significant etiologic role with respect to schizophrenia (Torrey, p. 9)." What Pollin and his colleagues found, instead, was that there were significant physiological conditions in the twins examined who had schizophrenia (p. 9).
The most significant findings were a history of lower birth weight and more obstetric complications in the affected twins in discordant pairs, and more neurological abnormalities in the affected twins (Pollin & Stabenau, 1968; Mosher et al., 1971). The findings, said these researchers, suggested that "the intrauterine experience of one twin, relative to the co-twin, tends to be…… [Read More]
(Human Genome Project, DNA Forensics, 2006) Examples of genetic testing use of DNA in forensic identification are: (1) identification of potential suspects from DNA left at crime scene; (2) exoneration of those wrongly accused of crimes; (3) identification of crime and catastrophe victims; (4) establishment of paternity and other family relationship; (5) identification of endangered and protected species in aiding wildlife officials and in prosecution of poachers; (6) detection of bacteria and other organisms that may be pollutants of air, water, soil and food; (7) matching of organ donors with recipients in transplant programs; (8) determination of pedigree for seed or livestock breeds; and (9) authentication of consumables such as caviar and wine. (U.S. Department of Justice, 2003; DNA Forensics, 2006) DNA typing is accomplished through obtaining DNA samples through designing "small pieces of DNA probes that will each seek out and bind to a complementary DNA sequence in the…… [Read More]
Ian Wimut and Keith Campell could effectively clone two sheeps named Megan and Morag in July 1995 from the differentiated emryo cells. (History of Cloning)
Dolly originated on July 5, 1996 as the first organism ever to e cloned from adult cells. Following the announcements for creation of Dolly y Ian Wilmut, an extensive deate on human cloning ethics emerged and that led President Clinton to propose for a five-year moratorium on federal as well as privately invested human cloning research on March 4, 1997. Richard Seed, a Havard graduate could announce on Decemer 5, 1997 aout his ojective of cloning a human eing prior to an of the process y enactment of the federal laws. Following the successful cloning of Dolly, Ian Wilmut and Keith Campell generated Polly, after cloning of a Poll Dorset lam from skill cells grown on a la and with its alteration genetically to incorporate…… [Read More]
PART 2-Historical Event
A specific historical event which has added to our understanding of certain aspects of the natural world is represented by the Chernobyl disaster. Which occurred in 1986. "The accident caused the largest uncontrolled radioactive release into the environment ever recorded for any civilian operation, and large quantities of radioactive substances were released into the air for about 10 days." (www.world-nuclear.org) in the period in which the accident took place, many countries were undergoing development processes. The international trend included an increased trust in the use of science and technology. Locally, while the importance of the central was understood, the same thing could not be stated about the risks it involved. It is believed that the accident was caused due to the lack of proper preparation of the workers.
The consequences of the explosion included the death of thirty workers and the contamination with thyroid cancer of…… [Read More]
raising IQ scores/Education. Question: Should the IQ cutoff for mental retardation be raised to 80? Six sources. APA.
Should the IQ Cutoff for Mental Retardation be raised to 80?
The debate regarding IQ tests continues to rage into the new millennium. Every decade has a myriad of new studies supporting or contradicting the last accepted theories and studies. There are new studies which indicate that the IQ scores in the United States has risen by 3 points per decade, "indicating that intelligence is not stable but is flexible with regards to environmental influences." However, after vast research, no one knows just exactly what is causing the rise in IQ scores. Moreover, there is an ongoing debate in regards to raising the IQ cutoff scores for the mental retardation assessment. The American Association of Mental Retardation's definition of mental retardation is "a disability characterized by significant limitations both in intellectual functioning…… [Read More]
genetics, largely the result of the completion of the Human Genome Project, has helped change the face of modern medicine. Genetic testing of an individual can not only help identify current diseases and disorders, but also help suggest treatment modalities and identify potential future illnesses. For example, patients with a family history of breast cancer can be tested for the breast-cancer gene, and, if positive, decide whether to pursue preventative therapies, such as pre-cancerous mastectomies. However, it is critical for healthcare workers to understand all of the ramifications of genetic testing so that they can answer patient questions about those tests. For example, if a genetic test can identify a disorder, but there is no preventative care or treatment for that disorder, will that knowledge help or harm the individual?
Lea, DH (2009). Basic genetics and genomics: A primer for nurses. The Online
Journal of Issues in Nursing, 14(2).…… [Read More]
In the world of medicine today, there is still much about the inner workings of the human brain that are relatively unknown. Yet advancements in brain scanning and other techniques are giving researchers greater insight on how epilepsy works and why the brain responds as it does to the seizures. Obviously, with advances in genetic testing and the existence of the Human Genome Project, epilepsy could one day be cured and thus help millions of sufferers to live a "normal" and non-disabling lifestyle.
Chadwick, David. Living with Epilepsy. London: Optima Publishing, 1987. (An excellent book which explains in-depth how a person can cope and live with epilepsy. It also provides information on support groups for those afflicted with the disease).
Preston, Robb. Epilepsy: Causes and Treatments. Miami, FL: Symposia Specialists, Inc., 1980. (Another excellent book that discusses all the major aspects of epilepsy. It also provides much information…… [Read More]
Criminal Justice Theory and the Los Angeles County Probation Department
Criminal and antisocial behaviors have been studied in the field of criminology for many years. Criminologists are very interested to learn what types of things cause specific criminal and antisocial behaviors. hile criminal behavior and antisocial behavior are not always related, they often have close ties. Criminologists and other researchers are looking to find commonalities between certain genetic makeups and deviant behavior. They believe that many people are genetically predisposed to be violent, and if these people can be located they can be treated.
That does not mean that criminologists are in favor of testing everyone's genetic makeup on the planet to see if any of them show violent tendencies. hat they are interested in doing, however, is studying criminals who already have a history of violent and deviant behavior to see what other traits they have, and what their…… [Read More]
James Dewey atson
The Discovery of DNA was one of the most important discoveries in the history of Humanity, and it was accomplished by James atson and Francis Crick. Their discovery of the structure of DNA allowed scientists to begin to understand the mechanism behind inheritance. hile many scientists over the years had studied heredity, beginning with Gregor Mendel, no one had been able to discover the exact mechanism for how heredity actually works. It was not until the technology of the time advance to a point where scientists could determine the structure of molecules that the discovery of the structure of genetic material could be determined. After much research, and some failures, two scientists, working together, finally determined the molecular structure of the genetic molecule, allowing for the study of the exact mechanism to begin. James atson was one of the scientists responsible for the discovery of the DNA…… [Read More]
Knowledge worker is someone employed more because of their specific informational expertise or mastery of a subject or process instead of their ability to perform manual or physical labor. These individuals will tend to advance the information available about their subject because they are able to devote their time and energy to focused analysis, or even redesign and development of a process. They are somewhat like the pure researchers of the past -- they work to solve particular problems, influence organizational decisions, and set priorities and strategies through their own intellectual curiosity. Most experts say that the real differentiation of knowledge working is that it is "non-routine" problem solving based on higher level thinking (Reinhardt, et.al., 2011).
The idea of acquiring and disseminating knowledge is certainly not new, nor is the philosophical paradigm of how humans acquire and process that same knowledge. To understand the modern version of knowledge working,…… [Read More]
In his seminal work, Second-Language Acquisition in Childhood, McLaughlin (1985) reports that early research into language acquisition by preschool children suggested that interference between languages is not as inevitable or universal as was once believed. "Contrastive analysis, in its traditional form, was not able to account for the vast majority of errors that second-language learners made; in fact, learners from quite different language backgrounds appeared to make the same types of mistakes in the target language," he adds (McLaughlin, 1985, p. 14).
Since these early studies into language acquisition, other studies have shown that transfer from the first language does take place in the speech of children from certain first-language backgrounds and at certain times during the learning process. Therefore, McLaughlin cautions that, "It is an exaggeration to say that transfer from the first language is minimal and unimportant. The acquisition of phonological, syntactic, and morphological structures in a…… [Read More]
The experiment was designed to first extract DNA, take it through the steps of amplification and detachment, and then prepare it for analysis. The question was what type of bacteria was being sequenced. The steps used were: 1) Extraction of genomic DNA, 2) Amplification of genetic region, 3) Verification, 4) Clean PC Products, 5) Quantify DNA concentration, 6) Cycle the sequence, and, 7) Precipitate cycle-sequenced products for analysis. In this case, a virtual laboratory was used, with the user being guided to the appropriate tools and equipment (Virtual Bacterial Identification).
Max ident gi|39295|Z11684.1
.henselae 16S rNA gene
Bartonella henselae 16S ribosomal NA, partial sequence
Discussion- The BLAST search displays the matching sequences in the database in descending order of the degree of the match. Most of the top scorers are either Bartonella henselae or ochalimaea…… [Read More]
medical care sector, the decisions of what services should be produced, how they should be produced, how they should be distributed, and how to allow for growth and innovation must be made.
What combination of non-medical and medical goods and services should be produced in the macro-economy? In terms of guns or butter, the optimal balance of the production of non-medical and medical goods and services in the macro-economy would also include adequate provisions for defense. In sum, to the extent that this combination favored non-medical and medical goods and services in the macro-economy would be the extent to which defense spending would be diminished in the production-possibility frontier (Bandyopadhyay & Sandler, 2014).
What particular medical goods and services should be produced in the health economy? There is a growing recognition that preventive health care services are far more cost effective than reactive approaches that only intervene when people develop…… [Read More]
That is simply because individual in the same family are much more likely than unrelated individuals to share similar foundational experiences by virtue of their exposure to similar parenting and resources in their immediate environment throughout their early lives (Gerrig & Zimbardo, 2007; utter, 2006). Just as hesus monkeys tend to adopt maternal behaviors and elements of personalities of their mothers irrespective of their genetic inclinations, so do human infants and growing children and adolescents internalize and adopt various aspects of the behaviors and reactions exhibited by their parents and other significant adult behavioral role models in their lives (Gerrig & Zimbardo, 2007).
The quality of resources available to siblings (such as food, medicine, educational opportunities, etc.) is generally very similar within biological families (Gerrig & Zimbardo, 2007; utter, 2006). To the extent these factors contribute to the development of behavior, it is extremely difficult if not impossible…… [Read More]
Early trauma that causes anger often corresponds to higher levels of aggression later in life, especially where the traumas are suppressed and internalized instead of being expressed at the time of their origin and at the source.
Furthermore, since many dysfunctional families forbid the expression of anger by children (particularly anger toward parents), individuals who experience significant levels of early trauma that produces repressed anger are often considerably more aggressive throughout life subsequently than individuals who were fortunate not to experience as much early trauma (Gerrig & Zimbardo 2005). Aggression is a known factor in criminal conduct as well as other forms of non-criminal negative social behavior such as those associated with overt prejudice and other types of social intolerance toward others (Macionis 2003).
Aggression and Prejudice:
One of the primary ways that aggression-prone individuals express their repressed rage is in their treatment of other less powerful individuals (Gerrig &…… [Read More]
Whereas it remains true that African-Americans and other racial minorities continue to be overrepresented in the American prison population, both common sense and the general consensus of the criminal justice community and sociological experts suggest that this hardly a direct function of race. ather, it merely reflects the unfortunate correlation between poverty, comparative lack of educational and employment opportunities in the American urban centers where many minorities reside, as well as of the social values that tend to prevail in many of those impoverished communities (Schmalleger 1997).
First, the quality of public school facilities and programs is directly related to the economic realities of their surrounding areas; second, within many segments of minority urban social culture, education is not valued the way it is in middle class and upper class communities and students who make the effort to apply themselves academically are more likely to be targeted for ridicule by…… [Read More]
Dahmer Forensic Analysis
Jeffrey Lionel Dahmer
Crime Scene and Discovery
Never before has egregious police incompetence hindered the apprehension of a serial killer as in the case of Jeffrey Dahmer. When police were called to investigate an alleged domestic disturbance between Konerak Sinthasomophone and Jeffrey Dahmer on May 27, 1991. Although two women came to the aide of Sinthasomophone and urged police to look further into the alleged dispute, the police ignored their pleas and Dahmer was able to convince them that Sinthasomophone was his 19-year-old lover; if police had bothered to check Sinthasomophone's identification they would have seen that he was in fact only 14 years old (ardsley, n.d.). Having convinced the police that Sinthasomophone and he were in the midst of a lovers' quarrel, Sinthasomophone was released into Dahmer's custody and by the end of the night, Sinthasomophone would become Dahmer's 13th victim (ardsley, n.d.). Dahmer would proceed…… [Read More]
It has been a long controversy about how nature and nurture imply to personality traits and human behavior. Nature means that genetic factor and the system of organs control the personality, while nurture means the personality is a result of conditioned circumstances where a person is brought up. It includes the personality of other people, like family, includes the teaching, and lessons a child gains during his/her mental development process.
Recent studies find more in human biological system that genes are related to people's behavior. McInerney (2001) shows, many researchers believe that genetics factors determine how someone will act and think in his or her life. Animal and human are born with specific character linked with the genetic information in the genes. It shapes each individual trait exclusively including the performance in social, interaction, intelligence, and adaptability to the surrounding community.
ehavior may change, he states, as a…… [Read More]
Treatment History Of Cystic Fibrosis
The field of pediatric nursing is a particularly large one in which its members may find themselves having to counsel both young patients and their families suffering from a myriad of diseases. Cystic fibrosis (CF), in particular, is a debilitating disease that strikes many young people. In the first years following its discovery, many children could not expect to make it to their teen years. Today, with advances in the management and care of this disease, patients are living into their 40s. It is even possible that there will one day be a cure.
This paper will look at CF from a historical perspective. The timeline of its discovery and research will be briefly presented, as will a few of the significant "milestones" in the history of the treatment of CF and what these mean for people battling this disease.
References to cystic fibrosis were…… [Read More]
Genetic screening is one of the most controversial topics in the scientific arena today. The advent of the Human Genome Project, which maps the complete human genetic code, has brought this issue to the forefront. This paper will discuss the basic science that underlies genetic screening, applications of genetic screening, and investigate some of the common misconceptions and ethical questions about its use.
Genetic screening itself is simply "the systematic search within a population for persons possessing particular genotypes, which are either associated with disease, predisposing to disease, or leading to disease in descendants" (Miller). In simpler terms, genetic screening involves testing and determining whether "an individual's genetic material to predict present or future disability or disease either for oneself or one's offspring" (McCarrick). Essentially, genetic screening is conducted for several basic reasons, including the care of the ill and the prevention of disease, providing reproductive information, determining the incidence…… [Read More]
GENETICALLY ENGINEERED FOOD OR ORGANISMS: SCIENCE'S ANSWER TO WORLD HUNGER
The introduction and use of genetically modified or engineered foods or organisms have attracted attention, mostly alarmed in recent years (WHO 2014). These foods are manufactured from organisms by artificially altering or engineering their DNA for nutrition purposes. This is done by infusing an edible plant gene into the organisms for immediate and ultimate purposes. One is to optimize production and increase the resistance to plant disease while tolerating the harmful effects of herbicides. Another is to extract them from genetically modified or GM microorganisms or animals for future use. Still another object or prospect is to alter the nutrients themselves in foods in order to control or prevent allergies they cause (WHO).
The target of the United Nations Organization's Millennium Development goals is to cut down the proportion of hunger this year into half (World Hunger Education Service, 2015).…… [Read More]
Huntington's disease (HD) was the first autonomic dominant disorder for which genetic prediction became possible" (Harper, et al., 2000, Journal of Medical Genetics, p. 567). HD is a disease that occurs due to an inherited disorder leading to the death of brain cells. A diagnosis of HD is accomplished through genetic testing which can be implemented at any age regardless of whether the symptoms manifest or not. Although, the specific symptoms vary between people, nevertheless, symptoms can start with people between 35 and 45 years of age and can also start in some individuals at even anearlier age. The disease may affect successive generations if health interventions are not implemented (Mandel, 2016).
Additionally, "the cause of HD is due to a dominant mutation of autosomal form of the gene called Huntington. This shows that a child born by an affected person has a 50% chance of developing or inheriting the…… [Read More]
However, while it is tempting to claim genetic influences as superior to environmental ones, there is still a great debate over whether and individual can overcome their genetics setbacks or be enhanced by their genetic superiority. The former is often achievable as in the case of the addict who has recovered from their addiction, the latter brings us to the morally trepidatious ground of eugenics where by genetic engineering can enhance the good traits and limit the bad traits. The problem there is who decides which traits to keep or loose? Usually decisions left up to a higher authority.
Gesell, A., Thompson, H., & Strunk, C. (1938). The Psychology of Early Growth: Including Norms of Infant Behavior and a Method of Genetic Analysis. New York: Macmillan.
Jang, K.L. (2005). The Behavioral Genetics of Psychopathology: A Clinical Guide. Mahwah, NJ: Lawrence Erlbaum Associates.
Johnson, A. (2003, February). The Genetic Key…… [Read More]
They're discussing them, talking to people from around the glove where the events unfolded, and then creating chat forums to engage in intellectual debate and sharing of ideas. They are talking about what the news media is reporting, whether or not it is slanted toward a political ideology, and assessing the information. Everyone, it seems, has faster access to broader sources of news and ideas, and they are using that information to form ideas and conclusions about political leaders and how those leaders respond to local, national, and world situations, people, and events.
How the Public Interprets Political Semantics and Use the Internet to Impact Policy and Government
One of the most significant examples of how the internet has facilitated the public's access to information, and how people world-wide have analyzed political semantics and used the information to shape policy and government is the second term of America's former President…… [Read More]
Nursing in 2021
Over the next decade, and for years to come afterwards, the expected growth in the older adult population will have a significant impact on the healthcare system. The baby boom generation, individuals born between 1946 and 1964, began turning 65 in 2011. By 2020 the number of Americans age 65 and older is expected to rise to 54 million. Furthermore, as a result of better nutrition, safety and health care the number of individuals who reach the age of 85 or older will grow even more dramatically ("The Impact of Aging Population on the Health Workforce in the United States," 2006).
This will precipitate a greater demand for health care in general and will also affect the nature of the skills and services the health care workforce must be equipped to provide, and the settings in which this care is provided. As a person ages, their immune…… [Read More]