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Various gene therapy-based tests have been conducted on the guinea pigs as model animals. The gene therapy-based experiments have shown that deafness can be cured with the help of gene therapy. One of the main reasons of the deafness is the destruction of hair cells in the cochlea. A gene that has been known to stimulate hair growth in the cochlea is Atoh1 and this gene has been tested by being delivered through adenovirus. When the gene was delivered with the adenovirus, the hair regrowth in the cochleae was triggered based on which more than 80% regrowth of the hearing was repaired. New experiments are being conducted on the delivery of genes that can repair errors in the messenger RNA because of the presence of defective and nonfunctional genes. Using this technique, cystic fibrosis, thalassemia and various kinds of leukemia can be treated (Wells, 2004, p. 1365).
Conclusion
The technique of gene therapy has great potential. There are a wide scope of medical disorders and conditions that have been treated by gene therapy. These include various forms of cancer. There is no doubt about the fact that the technique of gene therapy is very expensive but the scope that the...
(2006). Gene therapy progress and prospects: magnetic nanoparticle-based gene delivery. Gene Therapy 13, 283 -- 28.
Li, S., and Huang, L. (2007). Nonviral gene therapy: promises and challenges. Gene Therapy 7, 31 -- 34.
Niidome, T., and Huang, L. (2002). Gene Therapy Progress and Prospects: Nonviralvectors. Gene Therapy 9, 1647 -- 1652.
Niidome, T., and Huang, L. (2002). Gene Therapy Progress and Prospects: Nonviral vectors. Gene Therapy 9, 1647 -- 165.
Sinn, P.L., Sauter, S.L., and McCray, P.B. Jr. (2005). Gene Therapy Progress and Prospects: Development of improved lentiviral and retroviral vectors -- design, biosafety, and production. Gene Therapy 12, 1089 -- 1098.
U.S. Food and Drug Administration (2012, January 2). Cellular & Gene Therapy Guidances. Retrieved April 18, 2012, from http://www.fda.gov/BiologicsBloodVaccines/guidanceComplianceRegulatoryInformation/Guidances/CellularandGeneTherapy/default.htm
Wells, D.J. (2004). Gene Therapy Progress and Prospects: Electroporation and other physical methods. Gene Therapy 11, 1363 -- 1369.
References
Dobson, J. (2006). Gene therapy progress and prospects: magnetic nanoparticle-based gene delivery. Gene Therapy 13, 283 -- 28.
Li, S., and Huang, L. (2007). Nonviral gene therapy: promises and challenges. Gene Therapy 7, 31 -- 34.
Niidome, T., and Huang, L. (2002). Gene Therapy Progress and Prospects: Nonviralvectors. Gene Therapy 9, 1647 -- 1652.
Niidome, T., and Huang, L. (2002). Gene Therapy Progress and Prospects: Nonviral vectors. Gene Therapy 9, 1647 -- 165.
U.S. Food and Drug Administration (2012, January 2). Cellular & Gene Therapy Guidances. Retrieved April 18, 2012, from http://www.fda.gov/BiologicsBloodVaccines/guidanceComplianceRegulatoryInformation/Guidances/CellularandGeneTherapy/default.htm
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