Psycho Pharmalogical Approaches To Treat Psychopathology Nursing Term Paper

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Nursing: Psycho-Pharmalogical Approaches to Treat Psychopathology

The receptor activity is significant in creating the agonist or antagonist responses in neuroscience understanding; the constitutive receptor actions behave simply as competitive antagonist actions or agonist ones (Berg & Clarke, 2018). The tonic and basal levels of responses reduce the responses of agonist actions mainly on account of endogenous agonists. For instance, the neuro-actions created by drugs could be misunderstood because of a decrease in constitutive receptor activity, also known as inverse agonism (Berg & Clarke, 2018). Hence, the treatments for psychiatric disorders have to be suggested with careful contemplation since the need for proteins, enzymes, and certain dose-effect reactions vary from individual to individual. The tolerance and sensitization levels differ due to agonist drugs and their effect on the homeostatic compensatory mechanism, neurons, and neural circuitry adaption (Nutt, 2007).

There is a difference between G-coupled proteins and ion-gated channels. The G coupled proteins are diverse and can identify many ligands (Molecular Devices, n.a.). The ligands could include photons, proteins, and even small molecules. On the other hand, Ion channels are holes, apertures, or pores present in the cellular membrane that let ions come and go out of the cell.

The human genome has more than 400 genes for compensating the ion channels, which could help target drugs that present themselves as blockbusters (Molecular Devices,...…patients psychiatric condition as neural receptors would receive different levels of proteins, photons, or molecules released from the medicine formulas into the blood.

As cited before, most FDA-approved drugs impact G coupled proteins that stimulate chronic conditions and mental disorders; the nurses have to be knowledgeable in this regard to educate their patients about certain consequences in worse conditions. Coping skills and self-care techniques are to be taught to the patients, and the prescription of medications to manage side effects effectively. Response monitoring and management have to be prompt for handling the adverse events in times of crisis with accurate interventions for the timely stabilization of psychiatric conditions (Joyce University of Nursing…

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References

Berg, K. A., & Clarke, W. P. (2018). Making sense of pharmacology: Inverse agonism and functional selectivity. The International Journal of Neuropsychopharmacology, 21(10), 962–977. https://doi.org/10.1093/ijnp/pyy071

Joyce University of Nursing and Health Sciences. (2022, April 4). What is a psychiatric mental health nurse? https://www.joyce.edu/blog/what-is-mental-health-nursing/

Molecular Devices. (n.a.). GPCRs (G Protein-Coupled Receptors). https://www.moleculardevices.com/applications/g-protein-coupled-receptors#gref

Nutt, D. (2007). Key concepts in psychopharmacology. Psychiatry, 6(7), 263-267. http://www.med.monash.edu.au/assets/docs/scs/psychiatry/psychopharmacology/nutt-pharmacodynamics-2007.pdf

Stefanska, B., & MacEwan, D. J. (2015). Epigenetics and pharmacology. British Journal of Pharmacology, 172(11), 2701–2704. https://doi.org/10.1111/bph.13136


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