Cognitive Effects Of Risperidone In Children With Autism And Irritable Behavior Article Critique

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¶ … Autistic Children Children with autism and irritable behavior are an incredibly vulnerable population. The right medications are crucial because the children are the ones who suffer any social or emotional problems based on their conditions. That is why Aman et al. (2008) explored the use of risperidone in children with autism and other forms of irritable behavior. The study aimed to better understand risperidone's cognitive impact on children with severe behavior disturbances to test its efficiency as a potential solution to some of the children's behavioral issues.

Risperidone is an antipsychotic that is often administered to this vulnerable population; yet there is surprisingly little discourse on the cognitive impact it may have during treatment of behavioral disorders. The study conducted by Aman et al. (2008) aimed to test whether or not risperidone had a cognitive impact in the short-term during administering of treatment to children. During this age range, cognitive development is crucial for the lives of children. The researchers wanted to see if there were any positive or negative impacts of risperidone that were effecting cognitive development. Thus, the study included 38 children from 5 to 17 years of age over an eight-week...

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A control group took a placebo in this double blind study design. The null hypothesis was "that there would be no differences between placebo and risperidone" (Aman et al., 2008). Disproving the null hypothesis would show that there was a positive or negative correlation between cognitive development and treatments administering risperidone.
The study was properly set up for statistical testing. The study design was an "acute, double blind, placebo controlled, parallel groups design" administered at five different medical facilities (Aman et al., 2008). The independent variable was the administration of 3.5 mg of risperidone over an eight-week period. Dependent variables included the level of sustained attention in the children, verbal learning development, coordination, and spatial memory. The research did sufficiently explain each task that was administered at each clinical examination, which helped better explain the level of cognitive functioning seen in the subjects. Ultimately, the authors presented a strong description of their entire methodology which strengthened the study design and conclusions. There were a good collection of variables, although researchers should have…

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Aman, Michael, Hollway, Jill, McDougle, Christopher, Scahill, Lawrence, Tierny, Elaine, McCracken, James, Arnold, Eugene, Vitello, Benedetto, Ritz, Louise, Gavaletz, Allison, Cronin, Pegeen, Sweizy, Naomi, Wheeler, Courtney, Koening, Kathleen, Ghuman, Jaswinder, & Posey, David L. (2008). Cognitive effects of risperidone in children with autism and irritable behavior. Journal of Child and Adolescent Psychopharmacology, 18(3), 227-236.


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