NSAIDs Case Study Assignment
Nonsteroidal anti-inflammatory drugs(NSAIDs), also available on prescription, have been among the most regularly instructedpharmaceuticals in the universe: Ibuprofen and Aspirin. It is due to their broad spectrum of painkiller drugs andanti-inflammatory. The molecular formula of NSAIDs and their preference for cyclooxygenase are used to classify them. Therefore, this paper presents a case study of the 65 yr. Older man having chronic kidney disease after using NSAID Ibuprofen for a long time and case study of low dose aspirin by patients with coronary artery disease.
Based on many health conditions, the link involving kidney problems andibuprofen may occur immediatelyor after using it for a longer duration. Individuals with kidney impairment may get chronickidney disease when taking this NSAID. Nephropathy, a disorder that can emerge with lengthy usage ofibuprofen or other NSAID medications, may be detected as a relationship involving ibuprofen and kidney disease2. Treatment may reverse acute problems, but nephropathy may result in lasting harm. This is evident of the 65-year-old retired worker who used NSAIDIbuprofen for a long time hence having chronic kidney disease.
Ibuprofen is a painkiller that may be purchased in prescription. It operates by interfering with the body's synthesis of the prostaglandin hormone2. The medicine is available under numerous premium brands or elements to manage arthritis, acute dental discomfort, heat, anxiety, and other illnesses. After conducting trials on individuals with renal illness, researchers noted a link involving ibuprofen and kidney disease. A 65-year-old retired worker accorded dosages of the medicine developed nephropathy after using the drug for a long time due to his old age. The risk of renal illness from ibuprofen can be reduced by using the smallest amount feasible…identified as less prone to worsen. Low aspirin dosage is also occasionally utilized in preventive care in a primary sense, which is the containment of coronary heart disease before it occurs3. Nevertheless, new studies and suggestions show that only a tiny percentage of people opt to take aspirin in this method. Ibuprofen is not a good substitute for aspirin since, being a popular pain reliever, it might cause heart disease attacks by inhibiting the existence actions of aspirin.
Nonsteroidal anti-inflammatory medications (NSAIDs) are anti-inflammatory and painkiller treatments that are readily accessible. The arachidonic acid cycle enzymes are involved in their spectrum of activity. NSAIDs are among the most widely utilized prescribedmedications in the world. As per this case study, nonsteroidal anti-inflammatory drugs have been linked to acute renal damage in scientific journals andcoronary artery disease.
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In these cases, it has been mentioned that only those diabetics can benefit from the use of aspirin that have had a heart attack in the past. Thus, the usage of aspirin can help in prevention of any future heart attacks3 (p. 2365). Analysis of Chosen studies Study 1 The first study "Use of aspirin for primary and secondary prevention of cardiovascular disease in diabetic patients in an ambulatory care setting in
Aspirin -- Wonder Drug Today, we pretty much take aspirin for granted, but when it was developed it was a true "wonder" drug that could cure a variety of ills, and today, it still fits that bill. Aspirin was first discovered in 1897 by a German chemist, Dr. Felix Hoffman, who worked for the Bayer Company. He was looking for some kind of medication to help his father's suffering from rheumatism.
Aspirin from when it was first discovered to its relevant use today, and include when Aspirin was first discovered and its initial therapeutic use. It will also discuss today's therapeutic use to its initial market use. When Aspirin was first discovered, people considered it a wonder drug, and today, it is still one of the most commonly recognized and used drugs in the world. Aspirin has been replaced in
5% while 70.5% took Aspirin within six hours after reaching hospital and 76.5% of patients admitted in the NICVD were receiving Aspirin therapy." (Jaiwa, 2006, p.1) Jaiwa reports a more recent study that states findings that out of 52 patients with chest pain only 13 patients or 25% of the 52 received aspirin. The stated reason for not giving aspirin to the other 39 patients included that "chest pain was not
Aspirin is a most widely bought and used drugs for pain, fever and inflammation. Its main ingredient, salicylic acid, is irritating to the stomach and the drug must be modified. This experiment synthesizes aspirin with the use of salicylic acid as reactant. The experiment yielded a more acceptable, less irritating drug. Background of Experiment and Lab Concepts Present records say that more than 15,000 pounds of aspirin are sold daily (Smith n.d.).
Depending on society's trends and needs, individuals started to use Aspirin as a remedy for more and more medical conditions. It is, in point of fact, typical for a drug to be overshadowed by the interests of its promoters, the needs of its users, and its adverse effects. It is, thus, not surprising that particular substances come to be used for purposes other than those for which they were