Lessons In Theory Building Essay

Length: 5 pages Sources: 3 Subject: Evolution Type: Essay Paper: #26194039 Related Topics: Don Quixote, Strain Theory, Genetic Engineering, Biological Engineering
Excerpt from Essay :

Darwin's Theory Of Evolution

The construct of irreducible complexity is a pivotal aspect of genetic theory and of Darwinian theory. Irreducible complexity is a nexus of the older science of biology from which Darwin built his theory and modern genetic engineering. Darwin's words for irreducible complexity, most commonly associated with his argument about the construction of the eye, were "Organs of extreme perfection and complication," and Darwin further explicates,

"Reason tells me, that if numerous gradations from a simple and imperfect eye to one complex and perfect can be shown to exist, each grade being useful to its possessor, as is certainly the case; if further, the eye ever varies and the variations be inherited, as is likewise certainly the case and if such variations should be useful to any animal under changing conditions of life, then the difficulty of believing that a perfect and complex eye could be formed by natural selection, though insuperable by our imagination, should not be considered as subversive of the theory" (Darwin 1859).

Examples of irreducible complexity on the biological organ level include the heart, the eye, and the ear -- though they were not recognized an irreducible structures in Darwin's lifetime -- and there are, in fact, "tens of thousands of irreducibly complex systems on the cellular level" (Abbey, et al. 2011). Perhaps, in the construct of irreducible complexity, a foundation for intelligent design may be had, however, that line of reasoning is beyond the scope of this essay. The construct of irreducible complexity may be seen as a foundation of Darwin's theory of evolution, as Darwin observed that, "complex forms evolve from non-complex forms over time…based on natural selection, which acts to accumulate and transform minor advantageous genetic mutations" (Abbey, et al. 2005).

It is important to link the two disciplines since to argue for or against evidence of Darwin's theory without framing it in scientific progress is akin to claiming that Don Quixote cannot be the first modern novel because it is, after all, simply a written record of the ballads in the tradition of picaresque novel. Don Quixote was the novel of the time, indeed the only anti-romantic novel of the time, in quite the same way that the theory of evolution was the explanation for inherited biological difference that related to environmental survival.

One of the simplest examples of Darwin's theory of evolution can be accessed by referring to the study of peppered moths in English industrial cities. Peppered moths as a species present a variety of wing and body coloration patterns, which have apparently changed (evolved) over time (Majerus 2004). In 19th century England, people heated homes and factories and common spaces with coal burning furnaces, sans any type of filter that would reduce environmental pollution (Majerus 2004). As a result of this heavy pollution the lichen that grew on the trees under normal conditions killed the plant, and where the tree bark had once been light in color, it became darkened by deposits of coal soot (Majerus 2004). Indeed, the exteriors of buildings were also turned dark by the coal soot deposits. Unfortunately for some of the peppered moths, light colored wings stood out rather starkly on dark colored surfaces, which served to attract hungry, savvy birds to easy meals (Majerus 2004). The birds did not as readily pick off moths that were naturally located on the darker end of the wing and body color spectrum (Majerus 2004). As would be expected, more dark colored peppered moths survived in higher number and -- genetic heritability being what we know it is today -- passed on their dominant dark color to offspring in higher numbers (Majerus 2004). Critics of the peppered moth studies enjoy emphasizing that it is the frequency of the appearance of one or the other colored moth that was altered in concordance with the altered environment -- darker tree bark and buildings brought about changes in predation which resulted in a preponderance of darker moths. Yet, it is entirely possible in the long-term for the peppered moth to revert entirely to light winged and bodied variety as pollution has abated and environments have been cleaned up. What if all the dark moths developed a melanic-based disease and completely died off during a time when dark moths otherwise had higher survival rates? The important consideration...


Indeed, a cleaner English countryside and townships is seeing a resurgence of the lighter colored moths.

We may attribute our understanding of these genetic mechanisms to Gregor Mendel, who is associated with the discovery and articulation of the fundamental laws of trait heritability through his work on pea plants. Note that criticisms of Mendel's work are relatively rare, in that, Mendel did not associate or disassociate his discoveries with a higher being -- and drew no short lines between pea plants, monkeys, and human beings. Lui (2005) did examine the chronology of historical findings in the fields of biology and genetics to better determine the direction of influence for both Darwin and Mendel. Indeed, the influence that Darwin had on Mendel though The Origin, can be seen in the transmittal of the term gene, which was derived from pangen, a word coined by Darwin from Pangenesis (Lin 2005). Lin (2005) further clarifies the historical studies of the scientists,

"Darwin was the first to clearly describe almost all genetical phenomena of fundamental importance, and was the first to present a developmental theory of heredity -- Pangenesis, which not only greatly influenced many subsequent theories of inheritance, particularly those of de Vries, Galton, Brooks and Weismann, but also tied all aspects of variation, heredity, and development together, provided a mechanism for most of the observable facts, and is supported by increasing evidence" (1).

The theory of evolution is based on the natural selection of extant biological phenotypic traits. The process of natural selection, such as described above in the peppered moth example, can only eliminate traits and, perhaps, intensify existing traits. However, natural selection does not, in and of itself, create entirely new traits, a conundrum that requires a different theory to explain how new genetic information comes about. Darwin's theory of pangenesis was his attempt to offer an explanation for the occurrence of new genetic information that the creation of a new phenotypic variety would require. Theories are, according to the rules of science, intended to evolve, and are, in fact, the building blocks upon which positivist science [truth-seeking empiricism] is constructed -- one theory-building step after another. As such, the theory of pangenesis, which was "advocated by Darwin as the main source of genetic variety, has now been empirically disproved" (Bergman, 2006). For those who study and follow genetic science, pangenesis is of interest only as an historical theory, except that, as stated, theories have a way of evolving. Darwin's theory of pangenesis proposed that organism shed tiny particles called gemmules that transmit heritable characteristics from parents to offspring, and that environmentally altered gemmules will transmit as those modified particles. Francis Galton could not prove Darwin's theory with the science of his day, but new experiments indicate that successful induction of heritable modifications has been conducted. Indeed, "Detection of circulating nucleic acids and prions in plant sap and animal blood is considered as fresh evidence for the existence of gemmules" (Lui 2008). These new discoveries suggest that "a considerable revision of views on Darwin's Pangenesis must occur before a new comprehensive genetic theory can be achieved,"

In June 1909, Cambridge University hosted the 100th anniversary celebration of Charles Darwin's birth and the fiftieth anniversary of the publication of Origin of Species (Richmond 2006). The scientist gathered from round the globe to consider new developments, such as "the rediscovery of Mendel's laws of heredity, de Vriesin mutation theory, and the linkage of sex-cell division (recently named 'meiosis') to the mechanism of heredity" Richmond, 2006). At this historical watershed of modern biology, it was possible to "assess the status of evolution prior to the advent of the chromosome theory of genetics" (Redmond, 2006).

Darwin understood the constraints that common sense and conventional wisdom place on science, citing the ancient adage vox populi, vox dei (the voice of the people [is] the voice of God) "as every philosopher knows, cannot be trusted in science" (Darwin 1859). Yet, Darwin attempts to frame his argument in a later edition of The Origin, not is scientific terms, but in the lexicon of common sense.

"It is scarcely possible to avoid comparing the eye to a telescope. We know that this instrument has been perfected by the long-continued efforts of the highest human intellects; and we naturally infer that the eye has been formed by a somewhat analogous process. But may not this inference be presumptuous? Have we any right to assume that the Creator works by intellectual powers like those of man?...In living bodies, variation will cause the slight alterations, generation will multiply them almost infinitely,…

Sources Used in Documents:

Works Cited

Abalaka, M.E. & Abbey, F.K. (2011). Charles Darwin theory of evolution and modern genetic engineering. Journal of Pharmaceutical Research and Opinion, 1(7):174-177. 12 December 2014. Web. Retreived from http://innovativejournal.in/index.php/jpro/article/viewFile/685/592

Bergman, G. Pangenesis as a source of new genetic information. The history of a now disproven theory. Rivista di Biologia, 99(3): 425-43. 2006, September-December. Web. Retreived from http://www.ncbi.nlm.nih.gov/pubmed/17299698

Darwin, Charles. "Difficulties on theory." Chapter 6. On the Origin of Species by Means of Natural Selection, or the Preservation of Favoured Races in the Struggle for Life. (1st edition). 1859. Retrieved from http://friendsofdarwin.com/docs/origin-1/chapter-06/

Liu, Y. Darwin and Mendel: who was the pioneer of genetics? Rivista di Biologia, 98(2); 305-322. 2005. 12 December 2014. Web. Retreived from http://www.ncbi.nlm.nih.gov/pubmed/16180199
Lui, Y. A new perspective on Darwin's Pangenesis. Biological Reviews of Cambridge Philosophical Society, 83(2): 141-149. 2008. 12 December 2014. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/18429766
Richmond, M.L. The 1909 Darwin celebration. Reexamining evolution in the light of Mendel, mutation, and meiosis. Isis, 97(3): 447-484. 2006. 12 December 2014. Web. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/17059108

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